PANTHER Gene Information   
Gene Symbol(s): alph
Organism: Drosophila melanogaster
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Gene Name: Alphabet, isoform E
Gene ID: FBgn0086361
Protein ID: Q961C5
Persistent Id: PTN000352849
Alternate Ids:
15291681(GI) FBgn0086361(FlyBase)
Q961C5_DROME(UniProtKB-ID) AAN14176(EMBL-CDS)
FBgn0086361(Ensembl) AY051685(EMBL)
FBtr0085444(Ensembl_TRS) Q961C5(Synonym)
NP_651701(refSeq) 43481(GeneID)
FBpp0084810(Ensembl_PRO)
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PANTHER Classification
PANTHER Family: PROTEIN PHOSPHATASE (PTHR47992)
PANTHER Subfamily: ALPHABET, ISOFORM E (PTHR47992:SF63)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class: protein phosphatase
Pathway Categories: DPP-SCW signaling pathway
   protein phosphatase 2C alpha, beta
MYO signaling pathway
   protein phosphatase 2C alpha, beta
ALP23B signaling pathway
   protein phosphatase 2C alpha, beta
SCW signaling pathway
   protein phosphatase 2C alpha, beta
BMP/activin signaling pathway-drosophila
   protein phosphatase 2C alpha, beta
DPP signaling pathway
   protein phosphatase 2C alpha, beta
GBB signaling pathway
   protein phosphatase 2C alpha, beta
Activin beta signaling pathway
   protein phosphatase 2C alpha, beta

GO MF Complete: magnesium ion binding, protein serine/threonine phosphatase activity, manganese ion binding
GO BP Complete: dorsal closure, peptidyl-threonine dephosphorylation, imaginal disc fusion, thorax closure, determination of adult lifespan, response to paraquat, negative regulation of R7 cell differentiation, negative regulation of sevenless signaling pathway, negative regulation of photoreceptor cell differentiation, negative regulation of JNK cascade, regulation of p38MAPK cascade, mitotic cell cycle, response to oxidative stress, negative regulation of Ras protein signal transduction, negative regulation of ERK1 and ERK2 cascade, response to UV-C, negative regulation of stress-activated MAPK cascade, negative regulation of stress-activated protein kinase signaling cascade, dephosphorylation
GO CC Complete: nucleus, cytosol
Reactome Pathways: Generic Transcription Pathway, Signal Transduction, Immune System, Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer, Signaling by TGFB family members, Gene expression (Transcription), Signaling by TGF-beta Receptor Complex, Interferon Signaling, Downregulation of SMAD2/3:SMAD4 transcriptional activity, Cytokine Signaling in Immune system, Antiviral mechanism by IFN-stimulated genes, RNA Polymerase II Transcription, MTOR signalling, Energy dependent regulation of mTOR by LKB1-AMPK, ISG15 antiviral mechanism