PANTHER Gene Information   
Gene Symbol(s): nbs
Organism: Drosophila melanogaster
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Gene Name: Nibrin
Gene ID: FBgn0261530
Protein ID: Q9VT40
Persistent Id: PTN000255587
Alternate Ids:
Q9VT40_DROME(UniProtKB-ID) NM_143716(refSeq)
44259(GeneID) FBtr0306040(Ensembl_TRS)
FBpp0297182(Ensembl_PRO) FBgn0261530(FlyBase)
Q9VT40(Synonym) AE014296(EMBL)
FBgn0261530(Ensembl) AAF50215(EMBL-CDS)
386770909(GI)
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PANTHER Classification
PANTHER Family: NIBRIN-RELATED (PTHR12162)
PANTHER Subfamily: NIBRIN (PTHR12162:SF0)  
PANTHER GO-slim Molecular Function: damaged DNA binding
PANTHER GO-slim Biological Process: DNA duplex unwinding
mitotic G2 DNA damage checkpoint signaling
double-strand break repair via homologous recombination
PANTHER GO-slim Cellular Component: nuclear protein-containing complex
PANTHER protein class: damaged DNA-binding protein
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: damaged DNA binding
GO BP Complete: DNA repair, mitotic G2 DNA damage checkpoint signaling, DNA duplex unwinding, double-strand break repair via homologous recombination, signal transduction in response to DNA damage, telomere maintenance, intrinsic apoptotic signaling pathway in response to DNA damage, double-strand break repair via synthesis-dependent strand annealing, double-strand break repair
GO CC Complete: nucleus, Mre11 complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Cellular Senescence, DNA Repair, G2/M Checkpoints, Cell Cycle, Cellular responses to stress, Generic Transcription Pathway, Transcriptional Regulation by TP53, Sensing of DNA Double Strand Breaks, Homology Directed Repair, Regulation of TP53 Activity through Phosphorylation, Gene expression (Transcription), Regulation of TP53 Activity, Processing of DNA double-strand break ends, DNA Double Strand Break Response, HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA), DNA Double-Strand Break Repair, Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks, HDR through MMEJ (alt-NHEJ), Cellular responses to stimuli, Cell Cycle Checkpoints, RNA Polymerase II Transcription, G2/M DNA damage checkpoint, DNA Damage/Telomere Stress Induced Senescence

Orthologs