PANTHER Gene Information

Gene Symbol(s):

orb2

Organism:

Drosophila melanogaster

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Gene Name:

Translational regulator orb2

Gene ID:

FBgn0264307

Protein ID:

Q9VSR3

Persistent Id:

PTN001395516

Alternate Ids:

orb2{ECO:0000312\|EMBL:AAF50350.1}(Symbol)	7295024(GI)
AY052043(EMBL)	ORB2(Synonym)
FBgn0264307(Ensembl)	AAL25391(EMBL-CDS)
ORB2_DROME(UniProtKB-ID)	39018(GeneID)
FBgn0264307(FlyBase)	Q9VSR2(AltAccession)
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PANTHER Classification

PANTHER Family:	CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB (PTHR12566)
PANTHER Subfamily:	TRANSLATIONAL REGULATOR ORB2 (PTHR12566:SF12)
PANTHER GO-slim Molecular Function:	ribosome binding translation factor activity, RNA binding mRNA 3'-UTR binding
PANTHER GO-slim Biological Process:	negative regulation of translation
PANTHER GO-slim Cellular Component:	ribonucleoprotein complex nucleus neuron projection cytoplasm synapse
PANTHER protein class:	mRNA polyadenylation factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	identical protein binding, translation regulator activity, RNA binding, protein binding, translation activator activity, ribosome binding, mRNA regulatory element binding translation repressor activity, translation factor activity, RNA binding, mRNA 3'-UTR binding
GO BP Complete:	regulation of translation, long-term memory, sperm individualization, positive regulation of translation, spermatogenesis, male meiosis I, male courtship behavior, asymmetric cell division, sperm axoneme assembly, negative regulation of cytoplasmic translation, protein stabilization, negative regulation of translation
GO CC Complete:	synapse, synaptic membrane, neuron projection, axon terminus, dendrite terminus, nucleus, presynapse, perinuclear region of cytoplasm, postsynapse, cytoplasm, cell cortex, cell body, cytosol, protein-containing complex, axon

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=21746\|UniProtKB=Q8NE35	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000002753.5\|UniProtKB=A0A2I3SRF4	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000016441.3\|UniProtKB=A0A2I2ZU18	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000015050.4\|UniProtKB=A0A1D5RAX4	Macaca mulatta	O
MOUSE\|MGI=MGI=2443075\|UniProtKB=Q7TN99	Mus musculus	O
RAT\|RGD=1564670\|UniProtKB=D4AD99	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000015450.6\|UniProtKB=E1BGL3	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000010468.5\|UniProtKB=A0A287BC03	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000000077.4\|UniProtKB=A0A9L0SS07	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000032380.3\|UniProtKB=A0A2I2U7Z0	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845029945.1\|UniProtKB=A0A8I3Q2X6	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000006673.4\|UniProtKB=F6RDG8	Monodelphis domestica	O
CHICK\|Ensembl=ENSGALG00010021518.1\|UniProtKB=A0A8V0ZD11	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000006335.4\|UniProtKB=A0A803SSY2	Anolis carolinensis	O
XENLA\|Gene=LOC108697402\|UniProtKB=A0A8J1LDX4	Xenopus laevis	O
XENLA\|Gene=LOC108696127\|UniProtKB=A0A8J1L4V8	Xenopus laevis	O
ORYLA\|Ensembl=ENSORLG00000000726.2\|UniProtKB=H2L535	Oryzias latipes	O
DANRE\|Gene=cpeb3\|UniProtKB=A0A8M3AZE0	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000007131.1\|UniProtKB=W5MJS6	lepisosteus oculatus	O
HUMAN\|HGNC=21747\|UniProtKB=Q17RY0	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000017545.6\|UniProtKB=H2QS14	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010097.3\|UniProtKB=G3R3M7	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000019926.4\|UniProtKB=G7MU03	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1914829\|UniProtKB=Q7TN98	Mus musculus	LDO
RAT\|RGD=1311931\|UniProtKB=A0A0G2K3Y6	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000009995.6\|UniProtKB=E1BGL4	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000016981.5\|UniProtKB=A0A287BFV6	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000016921.4\|UniProtKB=A0A9L0TLK9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000031504.4\|UniProtKB=A0A2I2UQI8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845000511.1\|UniProtKB=A0A8I3MI16	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000006036.5\|UniProtKB=F6ZUD3	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010009389.1\|UniProtKB=A0A1D5P1V7	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000015039.4\|UniProtKB=A0A803SUH2	Anolis carolinensis	LDO
XENLA\|Gene=cpeb4.S\|UniProtKB=A0A8J1MNV6	Xenopus laevis	O
XENLA\|Gene=LOC108710949\|UniProtKB=A0A8J0UQE2	Xenopus laevis	LDO
XENTR\|Gene=cpeb4\|UniProtKB=A0A8J0R1W7	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000007328.2\|UniProtKB=A0A3B3IGT7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000001711.2\|UniProtKB=A0A3B3HQZ2	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-1557\|UniProtKB=Q7SXN4	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-170601-167\|UniProtKB=A0A0G2KYC0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000009131.1\|UniProtKB=W5MRX5	lepisosteus oculatus	LDO
HUMAN\|HGNC=21745\|UniProtKB=Q7Z5Q1	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000015924.5\|UniProtKB=H2QZF6	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000004449.3\|UniProtKB=A0A2I2YRC3	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000001384.4\|UniProtKB=F7D0U1	Macaca mulatta	O
MOUSE\|MGI=MGI=2442640\|UniProtKB=Q812E0	Mus musculus	O
RAT\|RGD=1307485\|UniProtKB=D3ZHK8	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000019847.6\|UniProtKB=F1N436	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000038410.3\|UniProtKB=A0A286ZUF4	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000008722.4\|UniProtKB=A0A3Q2HHQ6	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000027193.4\|UniProtKB=M3X804	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845001961.1\|UniProtKB=A0A8I3MI24	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000001149.5\|UniProtKB=A0A5F8GW79	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000003552.3\|UniProtKB=F7DQD2	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010010661.1\|UniProtKB=A0A8V0Y7I2	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000012015.3\|UniProtKB=H9GIH4	Anolis carolinensis	O
XENLA\|Gene=LOC108706545\|UniProtKB=A0A8J0UAI9	Xenopus laevis	O
XENLA\|Gene=LOC108698041\|UniProtKB=A0A1L8HTE0	Xenopus laevis	O
XENTR\|Gene=cpeb2\|UniProtKB=A0A8J0R0H3	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000016222.2\|UniProtKB=H2MNK4	Oryzias latipes	O
DANRE\|Gene=cpeb2\|UniProtKB=A0A8M1RRV8	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000009876.1\|UniProtKB=W5MUL4	lepisosteus oculatus	O
BRAFL\|Gene=LOC118414793\|UniProtKB=A0A9J7L2I6	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC584322\|UniProtKB=A0A7M7LVJ6	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00000771\|UniProtKB=Q18317	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00025614\|UniProtKB=Q6E3F3	Caenorhabditis briggsae	LDO
CAEEL\|WormBase=WBGene00001481\|UniProtKB=G5EBS6	Caenorhabditis elegans	O
CAEBR\|EnsemblGenome=WBGene00035332\|UniProtKB=Q6E3E1	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG22257\|UniProtKB=A8Y1X1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00000770\|UniProtKB=Q03571	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00031597\|UniProtKB=Q6E3D0	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00118117\|UniProtKB=A0A2A6CI86	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP002296\|UniProtKB=Q7QKF3	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC031499\|UniProtKB=A0A139WNN7	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_308504\|UniProtKB=E9G299	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW010113\|UniProtKB=B7PXJ3	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG79994\|UniProtKB=T1G3W2	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG69117\|UniProtKB=T1FZP8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG111676\|UniProtKB=T1EFD6	helobdella robusta	LDO
TRIAD\|EnsemblGenome=TriadG58533\|UniProtKB=B3S2Y8	Trichoplax adhaerens	LDO