PANTHER Gene Information

Gene Symbol(s):

AdamTS-A

Organism:

Drosophila melanogaster

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Gene Name:

ADAM metallopeptidase with thrombospondin type 1 motif A, isoform B

Gene ID:

FBgn0286071

Protein ID:

Q8SXB0

Persistent Id:

PTN000348032

Alternate Ids:

41887(GeneID)	FBgn0286071(FlyBase)
FBpp0082614(Ensembl_PRO)	45553379(GI)
Q8SXB0(Synonym)	FBtr0083160(Ensembl_TRS)
NP_996218(refSeq)	Q8SXB0_DROME(UniProtKB-ID)
AAM11069(EMBL-CDS)	AY094716(EMBL)
FBgn0286071(Ensembl)
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PANTHER Classification

PANTHER Family:	ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE (PTHR13723)
PANTHER Subfamily:	ADAM METALLOPEPTIDASE WITH THROMBOSPONDIN TYPE 1 MOTIF A, ISOFORM B (PTHR13723:SF278)
PANTHER GO-slim Molecular Function:	metalloendopeptidase activity
PANTHER GO-slim Biological Process:	proteolysis extracellular matrix organization
PANTHER GO-slim Cellular Component:	extracellular matrix
PANTHER protein class:	metalloprotease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	zinc ion binding, metalloendopeptidase activity
GO BP Complete:	epithelial cell migration, open tracheal system, mesodermal cell migration, proteolysis, extracellular matrix organization, germ cell migration, larval salivary gland morphogenesis
GO CC Complete:	extracellular matrix

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

O-linked glycosylation, O-glycosylation of TSR domain-containing proteins, Metabolism of proteins, Post-translational protein modification

Orthologs

ID	Organism	Type
HUMAN\|HGNC=220\|UniProtKB=O75173	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000001576.6\|UniProtKB=A0A2I3T896	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000007720.3\|UniProtKB=G3QXK7	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000050419.1\|UniProtKB=G7ME94	Macaca mulatta	O
MOUSE\|MGI=MGI=1339949\|UniProtKB=Q8BNJ2	Mus musculus	O
RAT\|RGD=621242\|UniProtKB=Q9ESP7	Rattus norvegicus	O
BOVIN\|Gene=ADAMTS4\|UniProtKB=Q9TT93	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000013210.6\|UniProtKB=G8JKX1	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000006359.5\|UniProtKB=F1S1A7	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000024172.3\|UniProtKB=F6YRD3	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000000494.6\|UniProtKB=A0A2I2V2F1	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845029491.1\|UniProtKB=A0A8I3Q3A2	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000005192.5\|UniProtKB=F7DMX5	Monodelphis domestica	O
CHICK\|Ensembl=ENSGALG00010027561.1\|UniProtKB=A0A8V1A4N2	Gallus gallus	O
XENLA\|Gene=adamts4.L\|UniProtKB=A0A1L8FD05	Xenopus laevis	O
XENLA\|Gene=adamts4.S\|UniProtKB=A0A1L8F4Z5	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-996659\|UniProtKB=F7B862	Xenopus tropicalis	O
HUMAN\|HGNC=217\|UniProtKB=Q9UHI8	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000013813.5\|UniProtKB=H2QKW0	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000007355.3\|UniProtKB=G3QWN6	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000013407.4\|UniProtKB=G7MNA9	Macaca mulatta	O
MOUSE\|MGI=MGI=109249\|UniProtKB=P97857	Mus musculus	O
RAT\|RGD=621241\|UniProtKB=Q9WUQ1	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000000706.4\|UniProtKB=A7MB07	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000012026.5\|UniProtKB=F1SHP1	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000016339.4\|UniProtKB=F6YLN3	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000013323.6\|UniProtKB=M3WIN4	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845018006.1\|UniProtKB=A0A8I3P1X0	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000021000.4\|UniProtKB=F6RJW6	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000047416.1\|UniProtKB=A0A6I8N090	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010010659.1\|UniProtKB=A0A8V0Y1A4	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000014530.4\|UniProtKB=G1KQ54	Anolis carolinensis	O
XENLA\|Gene=adamts1.L\|UniProtKB=Q5U261	Xenopus laevis	O
XENLA\|Gene=adamts1.S\|UniProtKB=A0A8J0UHZ0	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-492600\|UniProtKB=B2GUP2	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000004990.2\|UniProtKB=Q4AED3	Oryzias latipes	O
DANRE\|Gene=adamts1\|UniProtKB=A0A8M9PWV9	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000010782.1\|UniProtKB=W5MXV6	lepisosteus oculatus	O
HUMAN\|HGNC=221\|UniProtKB=Q9UNA0	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000013814.4\|UniProtKB=K7C8I8	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000006998.3\|UniProtKB=G3QVR6	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000013405.4\|UniProtKB=F6Z3S6	Macaca mulatta	O
MOUSE\|MGI=MGI=1346321\|UniProtKB=Q9R001	Mus musculus	O
RAT\|RGD=735196\|UniProtKB=G3V673	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000000648.4\|UniProtKB=F1MRZ2	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000012027.5\|UniProtKB=F1SHP0	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000006500.4\|UniProtKB=A0A5F5PZN1	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000002300.6\|UniProtKB=M3VY90	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845018095.1\|UniProtKB=A0A8I3P533	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000020998.4\|UniProtKB=F6RJX5	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000047716.1\|UniProtKB=A0A6I8NAA2	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010010712.1\|UniProtKB=A0A8V0Y665	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000014354.3\|UniProtKB=G1KPY2	Anolis carolinensis	O
XENLA\|Gene=adamts5.L\|UniProtKB=A0A1L8HCN5	Xenopus laevis	O
XENLA\|Gene=adamts5.S\|UniProtKB=A0A1L8H558	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-961098\|UniProtKB=A0A6I8R102	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000004966.2\|UniProtKB=A0A3B3HJD8	Oryzias latipes	O
DANRE\|Gene=adamts5\|UniProtKB=G3G3J8	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000010800.1\|UniProtKB=W5MXY1	lepisosteus oculatus	O
HUMAN\|HGNC=224\|UniProtKB=Q9UP79	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000004483.6\|UniProtKB=H2Q549	Pan troglodytes	O
MACMU\|Ensembl=ENSMMUG00000003300.4\|UniProtKB=F7FFM2	Macaca mulatta	O
MOUSE\|MGI=MGI=1353468\|UniProtKB=P57110	Mus musculus	O
RAT\|RGD=1308511\|UniProtKB=D4AAT1	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000010411.6\|UniProtKB=F1MP11	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000015249.5\|UniProtKB=A0A287B8M3	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000014164.3\|UniProtKB=F6ZXN7	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000027680.4\|UniProtKB=A0A337S1I2	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845006356.1\|UniProtKB=A0A8I3NE19	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000005108.5\|UniProtKB=F6ZDR1	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000012480.4\|UniProtKB=F7FTW7	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010022959.1\|UniProtKB=A0A8V0ZKD7	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000017709.4\|UniProtKB=H9GPK1	Anolis carolinensis	O
XENLA\|Gene=adamts8.L\|UniProtKB=A0A1L8FL27	Xenopus laevis	O
XENLA\|Gene=LOC108695817\|UniProtKB=A0A8J0T8V1	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-994782\|UniProtKB=A0A8J0QSE7	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000015206.2\|UniProtKB=H2MK48	Oryzias latipes	O
DANRE\|Gene=adamts8a\|UniProtKB=A0A8M9QEM5	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000004181.1\|UniProtKB=W5M9J1	lepisosteus oculatus	O
HUMAN\|HGNC=16305\|UniProtKB=Q8TE58	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000004484.3\|UniProtKB=H2Q550	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000007508.3\|UniProtKB=G3QX19	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000003301.4\|UniProtKB=F7FFL7	Macaca mulatta	O
MOUSE\|MGI=MGI=2449569\|UniProtKB=P59384	Mus musculus	O
RAT\|RGD=1309770\|UniProtKB=D3ZXM1	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000016857.5\|UniProtKB=E1BN99	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000015250.3\|UniProtKB=F1S6D2	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000015715.3\|UniProtKB=F6V0J9	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000008344.5\|UniProtKB=M3W9E9	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845006293.1\|UniProtKB=A0A8I3MRT7	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000005161.4\|UniProtKB=F7E8C6	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000048042.1\|UniProtKB=A0A6I8NWD9	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010022967.1\|UniProtKB=E1BX45	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000017722.3\|UniProtKB=H9GPK4	Anolis carolinensis	O
XENLA\|Gene=adamts15.S\|UniProtKB=A0A1L8FFP2	Xenopus laevis	O
XENLA\|Gene=adamts15.L\|UniProtKB=A0A1L8FL13	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-6051208\|UniProtKB=A0A6I8T030	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000007584.2\|UniProtKB=H2LTT5	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000015202.2\|UniProtKB=H2MK41	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-070814-5\|UniProtKB=X1WDJ8	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-060526-203\|UniProtKB=A2BIA3	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000004241.1\|UniProtKB=W5M9N9	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000023761.1\|UniProtKB=Q1RLE7	Ciona intestinalis	O
HUMAN\|HGNC=17178\|UniProtKB=P59510	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000004841.6\|UniProtKB=A0A2I3SPX7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000002541.4\|UniProtKB=G3QJC2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000013942.4\|UniProtKB=F6SF07	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2660628\|UniProtKB=P59511	Mus musculus	LDO
RAT\|RGD=1307725\|UniProtKB=A0A0G2K836	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000000395.4\|UniProtKB=E1B900	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000000795.5\|UniProtKB=F1SH01	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000020835.3\|UniProtKB=F6PZV0	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000010889.6\|UniProtKB=M3WE50	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845029722.1\|UniProtKB=A0A8I3Q4T9	Canis lupus familiaris	LDO
ORNAN\|Ensembl=ENSOANG00000004962.4\|UniProtKB=F7DJ37	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010001858.1\|UniProtKB=A0A8V0X7B5	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000003071.4\|UniProtKB=A0A803TYY5	Anolis carolinensis	LDO
XENLA\|Gene=LOC108710260\|UniProtKB=A0A8J1MMQ3	Xenopus laevis	LDO
XENTR\|Gene=adamts20\|UniProtKB=A0A8J0QMJ1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000003194.2\|UniProtKB=H2LDH7	Oryzias latipes	LDO
DANRE\|Gene=LOC101886654\|UniProtKB=A0A8M6Z4V2	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000001507.1\|UniProtKB=W5M095	lepisosteus oculatus	LDO
HUMAN\|HGNC=13202\|UniProtKB=Q9P2N4	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000015082.6\|UniProtKB=H2QMW5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000015540.4\|UniProtKB=A0A2I2ZAM7	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000000265.4\|UniProtKB=F7H0I0	Macaca mulatta	O
MOUSE\|MGI=MGI=1916320\|UniProtKB=E9PUN6	Mus musculus	O
RAT\|RGD=1306889\|UniProtKB=D3ZMB0	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000003165.5\|UniProtKB=E1BI72	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000011496.5\|UniProtKB=A0A287AEN1	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000019880.4\|UniProtKB=F6VTC7	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000001564.6\|UniProtKB=M3VWV5	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845012850.1\|UniProtKB=A0A8I3NK12	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000003140.4\|UniProtKB=F6WUL8	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000002273.3\|UniProtKB=A0A6I8NMK3	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010020246.1\|UniProtKB=A0A8V0ZDV3	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000000597.3\|UniProtKB=H9G4D0	Anolis carolinensis	O
XENLA\|Gene=adamts9.S\|UniProtKB=A0A8J1KK78	Xenopus laevis	O
XENLA\|Gene=adamts9.L\|UniProtKB=A0A8J1MYA0	Xenopus laevis	O
XENTR\|Gene=adamts9\|UniProtKB=A0A8J0QI19	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000008082.2\|UniProtKB=H2LVL3	Oryzias latipes	O
DANRE\|Gene=adamts9\|UniProtKB=G3G3K0	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000010273.1\|UniProtKB=W5MW32	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000007281.3\|UniProtKB=F6SUU2	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118415541\|UniProtKB=A0A9J7L4W5	Branchiostoma floridae	LDO
BRAFL\|Gene=LOC118416374\|UniProtKB=A0A9J7L735	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC586332\|UniProtKB=A0A7M7MYB5	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00001650\|UniProtKB=Q19791	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG03449\|UniProtKB=A8WV33	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00095949\|UniProtKB=A0A2A6CAU8	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP004201\|UniProtKB=A0A1S4GKV4	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC015139\|UniProtKB=D2A5N5	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_303360\|UniProtKB=E9GFV5	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW021991\|UniProtKB=B7QFZ7	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g95408\|UniProtKB=A7RW19	Nematostella vectensis	LDO
DICDI\|dictyBase=DDB_G0279795\|UniProtKB=O15916	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_46880\|UniProtKB=F0ZGR2	Dictyostelium purpureum	O
SELML\|EnsemblGenome=SELMODRAFT_425768\|UniProtKB=D8SU81	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_417729\|UniProtKB=D8S3E8	Selaginella moellendorffii	O