PANTHER Gene Information

Gene Symbol(s):

manA

Organism:

Escherichia coli

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Gene Name:

Mannose-6-phosphate isomerase

Gene ID:

BAA15361

Protein ID:

P00946

Persistent Id:

PTN000816424

Alternate Ids:

MANA_ECOLI(UniProtKB-ID)	Phosphohexomutase(Synonym)
WP_001170664(refSeq)	CHEMBL3309019(ChEMBL)
AAC74685(Ensembl_TRS)	manA(Symbol)
AAA79050(EMBL-CDS)	U00096(EMBL)
5.3.1.8(EC)	MetaCyc:MANNPISOM-MON(BioCyc)
BAA15361(Ensembl_PRO)	808730555(GI)
944840(GeneID)	BAA15361(Ensembl)
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PANTHER Classification

PANTHER Family:	MANNOSE-6-PHOSPHATE ISOMERASE (PTHR10309)
PANTHER Subfamily:	MANNOSE-6-PHOSPHATE ISOMERASE (PTHR10309:SF0)
PANTHER GO-slim Molecular Function:	isomerase activity
PANTHER GO-slim Biological Process:	nucleotide-sugar metabolic process nucleobase-containing compound biosynthetic process carbohydrate derivative biosynthetic process
PANTHER GO-slim Cellular Component:	cytosol
PANTHER protein class:	isomerase

Pathway Categories:

Mannose metabolism

Mannose 6-P isomerase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	zinc ion binding, protein binding, metal ion binding, mannose-6-phosphate isomerase activity, isomerase activity
GO BP Complete:	carbohydrate metabolic process, mannose catabolic process, GDP-mannose biosynthetic process, colanic acid biosynthetic process
GO CC Complete:	cytoplasm, cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=7216\|UniProtKB=P34949	Homo sapiens	LDO
PANTR\|Gene=MPI\|UniProtKB=A5A6K3	Pan troglodytes	LDO
PANTR\|Ensembl=ENSPTRG00000007287.7\|UniProtKB=H2Q9T4	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000014749.3\|UniProtKB=G3RFM0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000005227.4\|UniProtKB=G7MYC5	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97075\|UniProtKB=Q924M7	Mus musculus	LDO
RAT\|RGD=3107\|UniProtKB=Q68FX1	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000005845\|UniProtKB=Q3SZI0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000024990.4\|UniProtKB=A0A287BNZ5	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000011033.4\|UniProtKB=A0A9L0S621	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000003835.6\|UniProtKB=A0A337SGZ2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845018367.1\|UniProtKB=A0A8I3P413	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000009245.4\|UniProtKB=A0A5F8G5T3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000006529.3\|UniProtKB=F6YAT8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010023456.1\|UniProtKB=A0A1D5Q008	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000004579.3\|UniProtKB=A0A803U1F0	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000017077.3\|UniProtKB=H9GNX5	Anolis carolinensis	LDO
XENLA\|Gene=mpi.L\|UniProtKB=A0A8J0UV87	Xenopus laevis	LDO
XENLA\|Gene=mpi.S\|UniProtKB=A0A8J0UWU0	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-973629\|UniProtKB=F6UTY7	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000001616.2\|UniProtKB=A0A3B3ICK2	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050904-6\|UniProtKB=Q3ZB95	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000014939.1\|UniProtKB=W5NCN5	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000005335.3\|UniProtKB=F7B5B2	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_57753\|UniProtKB=C3Y7W9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118428177\|UniProtKB=A0A9J7M3G6	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC574815\|UniProtKB=A0A7M7RBS3	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00015464\|UniProtKB=O16315	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00038390\|UniProtKB=A8XUU8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00115135\|UniProtKB=A0A2A6C1Y8	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00014013\|UniProtKB=P34650	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG09990\|UniProtKB=A8XA43	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00276697\|UniProtKB=A0A2A6CFK8	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0286506\|UniProtKB=Q9VH77	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP000053\|UniProtKB=Q7QEL8	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC007395\|UniProtKB=D1ZZV1	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_128126\|UniProtKB=E9GEW1	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW010706\|UniProtKB=B7Q7R0	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG166495\|UniProtKB=T1EY64	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g169651\|UniProtKB=A7SEE9	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG30639\|UniProtKB=B3S7P3	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_38716\|UniProtKB=A9V9P8	Monosiga brevicollis	LDO
YEAST\|SGD=S000000805\|UniProtKB=P29952	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_ADR003C\|UniProtKB=Q75AB5	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000189115\|UniProtKB=P34948	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_B18348g\|UniProtKB=Q6CE59	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_01715\|UniProtKB=C8VNW5	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_4G08410\|UniProtKB=Q4WP88	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU02322\|UniProtKB=Q7S4U2	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_10384\|UniProtKB=A7EYG8	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_07518\|UniProtKB=Q0UL46	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_00667\|UniProtKB=P29951	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G13280\|UniProtKB=Q66WM4	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU07165\|UniProtKB=Q870Y1	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_01063\|UniProtKB=A7E6Y7	Sclerotinia sclerotiorum	LDO
SCHPO\|PomBase=SPBC2G2.16\|UniProtKB=O43014	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02648\|UniProtKB=B6K0T4	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNJ01750\|UniProtKB=Q5KAG8	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNI02370\|UniProtKB=Q9HFU4	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_06167\|UniProtKB=A0A0D1BUK2	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_07085\|UniProtKB=E3KAQ7	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_33280\|UniProtKB=F4P4N2	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_002010\|UniProtKB=B1N3V1	Entamoeba histolytica	LDO
ENTH1\|EnsemblGenome=CL6EHI_162210\|UniProtKB=C4M8I8	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0284685\|UniProtKB=Q54PA0	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_26332\|UniProtKB=F0Z8K8	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_32_1580\|UniProtKB=Q4Q5C3	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.01.6410\|UniProtKB=Q381V7	Trypanosoma brucei	LDO
TRIV3\|Gene_ORFName=TVAG_343390\|UniProtKB=A2E1E3	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_0801800\|UniProtKB=Q8IAL6	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00037709001\|UniProtKB=A0CEQ3	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_9679\|UniProtKB=B8CBZ4	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GGZ4_PHYRM\|UniProtKB=H3GGZ4	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_02g147650v5\|UniProtKB=A0A2K3E3M9	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00079p00142130\|UniProtKB=W1P2B0	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_105G00290\|UniProtKB=A0A0K9Q632	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_99G00800\|UniProtKB=A0A0K9NHD8	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma01_g14380\|UniProtKB=A0A804HU10	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma11_g11930\|UniProtKB=A0A804L6X8	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_026349mg\|UniProtKB=K3ZIE7	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3005G176100\|UniProtKB=A0A1B6PT89	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb167360\|UniProtKB=A0A804NKI2	Zea mays	O
BRADI\|EnsemblGenome=BRADI_4g14237v3\|UniProtKB=I1IKK4	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0359960\|UniProtKB=A0A287NPP0	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS4A02G163500\|UniProtKB=A0A3B6HT20	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4D02G150300\|UniProtKB=A0A3B6JI36	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4B02G149400\|UniProtKB=A0A3B6IQ29	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_001484mg\|UniProtKB=K3XHW2	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3003G087900\|UniProtKB=A0A1B6Q259	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb266540\|UniProtKB=A0A804PTM9	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb230120\|UniProtKB=A0A804PE46	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb125530\|UniProtKB=B4FPI5	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os01g0127900\|UniProtKB=Q9FTR6	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_2g01950v3\|UniProtKB=I1HBM0	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0222320\|UniProtKB=A0A8I6WY65	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS3B02G039000\|UniProtKB=A0A3B6FF83	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3A02G044800\|UniProtKB=A0A3B6E9R0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3D02G036100\|UniProtKB=A0A3B6GM47	Triticum aestivum	LDO
NELNU\|Gene=LOC104602920\|UniProtKB=A0A1U8AQ79	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110801609\|UniProtKB=A0A9R0J856	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr12g0550701\|UniProtKB=A0A251T3D9	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr15g0681671\|UniProtKB=A0A251S6A6	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C600303730\|UniProtKB=A0A9R1VAS6	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C300132280\|UniProtKB=A0A9R1W857	Lactuca sativa	O
HELAN\|EnsemblGenome=HanXRQr2_Chr09g0394411\|UniProtKB=A0A251T9L0	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C400216600\|UniProtKB=A0A9R1VSK5	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a006972mg\|UniProtKB=A0A022R2G6	Erythranthe guttata	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a0065651mg\|UniProtKB=A0A022RX47	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_06482\|UniProtKB=A0A2G3AAT7	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400026392\|UniProtKB=M1CHZ5	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc02g086095.1\|UniProtKB=A0A3Q7F950	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107772367\|UniProtKB=A0A1S3Y5J4	Nicotiana tabacum	O
TOBAC\|Gene=LOC107812706\|UniProtKB=A0A1S4BX42	Nicotiana tabacum	LDO
CAPAN\|EnsemblGenome=T459_11734\|UniProtKB=A0A1U8GQ16	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400011772\|UniProtKB=M1AUP3	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc06g060100.3\|UniProtKB=A0A3Q7GUL2	Solanum lycopersicum	O
TOBAC\|Gene=LOC107771722\|UniProtKB=A0A1S3Y3E7	Nicotiana tabacum	O
TOBAC\|Gene=LOC107802884\|UniProtKB=A0A1S4AZ59	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_04228\|UniProtKB=A0A1U8FQY4	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400010399\|UniProtKB=M1ANX7	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc02g063220.3\|UniProtKB=A0A3Q7F0W1	Solanum lycopersicum	O
TOBAC\|Gene=LOC107797458\|UniProtKB=A0A1S4AHD4	Nicotiana tabacum	O
TOBAC\|Gene=LOC107789518\|UniProtKB=A0A1S3ZQM9	Nicotiana tabacum	O
VITVI\|Gene_OrderedLocusName=VIT_01s0011g03750\|UniProtKB=F6HFN4	Vitis vinifera	O
CITSI\|Gene_ORFName=CISIN_1g014147mg\|UniProtKB=A0A067GNE7	Citrus sinensis	O
RICCO\|Gene_ORFName=RCOM_1309320\|UniProtKB=B9SLX4	Ricinus communis	O
CUCSA\|EnsemblGenome=Csa_5G167200\|UniProtKB=A0A0A0KL16	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_1G313500\|UniProtKB=M5XC42	Prunus persica	O
VITVI\|EnsemblGenome=Vitvi14g01178\|UniProtKB=F6HSR9	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_F02498\|UniProtKB=A0A059BS81	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C02P22400.1\|UniProtKB=A0A078HX57	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A02P13900.1\|UniProtKB=A0A078FHG5	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra034030\|UniProtKB=A0A3P6A6P1	Brassica campestris	LDO
ARATH\|TAIR=locus=2019748\|UniProtKB=Q9FZH5	Arabidopsis thaliana	LDO
BRANA\|Gene_ORFName=GSBRNA2T00057273001\|UniProtKB=A0A078HD56	Brassica napus	O
BRANA\|EnsemblGenome=GSBRNA2T00064404001\|UniProtKB=A0A078JP95	Brassica napus	O
BRACM\|EnsemblGenome=Bra021430\|UniProtKB=M4DY34	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_A05P45250.1\|UniProtKB=A0A078J274	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00049577001\|UniProtKB=A0A078FES7	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00013785001\|UniProtKB=A0A078IY79	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C09P75770.1\|UniProtKB=A0A078I0X7	Brassica napus	O
BRACM\|EnsemblGenome=Bra039181\|UniProtKB=A0A397ZGP6	Brassica campestris	O
ARATH\|TAIR=locus=2076864\|UniProtKB=Q9M884	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107916682\|UniProtKB=A0A1U8KGB1	Gossypium hirsutum	O
GOSHI\|Gene=LOC107912733\|UniProtKB=A0A1U8K1U8	Gossypium hirsutum	O
GOSHI\|Gene=LOC107935810\|UniProtKB=A0A1U8MAQ2	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_019440\|UniProtKB=A0A061EIH3	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g013464mg\|UniProtKB=A0A067F747	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_017G115500v3\|UniProtKB=A0A2K1X6N8	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_004G099100v3\|UniProtKB=B9H303	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_02G069000\|UniProtKB=A0A2C9WE65	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_01G110800\|UniProtKB=A0A2C9WJR8	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1166790\|UniProtKB=B9SZQ6	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_13G045700\|UniProtKB=I1LX30	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_19G049300\|UniProtKB=A0A0R0EI48	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_08G365900\|UniProtKB=I1KZL9	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_18G296300\|UniProtKB=I1N5B5	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_7g007320\|UniProtKB=A0A072TVL2	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr01_07400\|UniProtKB=A0A2I4EBP2	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G300600\|UniProtKB=A0A0A0L9Y1	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_3G142100\|UniProtKB=A0A251Q011	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_125724\|UniProtKB=D8SVH8	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c6_14770\|UniProtKB=A0A2K1KFL2	Physcomitrella patens	LDO
PHYPA\|EnsemblGenome=Pp3c16_5490\|UniProtKB=A0A2K1J7A3	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0082s0088\|UniProtKB=A0A2R6WKB4	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001210110\|UniProtKB=A0A1Y1I1U7	Klebsormidium nitens	LDO
STRCO\|Gene_OrderedLocusName=SCO3025\|UniProtKB=Q9KZL9	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv3255c\|UniProtKB=O05898	Mycobacterium tuberculosis	LDO
VIBCH\|EnsemblGenome=VC_0269\|UniProtKB=Q9KV87	Vibrio cholerae	O
VIBCH\|EnsemblGenome=VC_1827\|UniProtKB=Q9KR20	Vibrio cholerae	LDO
SALTY\|EnsemblGenome=STM1467\|UniProtKB=P25081	Salmonella typhimurium	LDO
YERPE\|Gene_OrderedLocusName=YPO2263\|UniProtKB=A0A5P8YFI9	Yersinia pestis	LDO