PANTHER Gene Information

Gene Symbol(s):

kbl

Organism:

Escherichia coli

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Gene Name:

2-amino-3-ketobutyrate coenzyme A ligase

Gene ID:

BAE77675

Protein ID:

P0AB77

Persistent Id:

PTN000343994

Alternate Ids:

P07912(AltAccession)	NC_000913(refSeq)
948138(GeneID)	KBL_ECOLI(UniProtKB-ID)
AKB ligase {ECO:0000255\|HAMAP-Rule:MF_00985}(Synonym)	AAC76641(Ensembl_PRO)
AAB18594(EMBL-CDS)	X06690(EMBL)
808715348(GI)	b3617(Ensembl)
AAC76641(Ensembl_TRS)	kbl{ECO:0000255\|HAMAP-Rule:MF_00985}(Symbol)
MetaCyc:AKBLIG-MON(BioCyc)	2.3.1.29 {ECO:0000255\|HAMAP-Rule:MF_00985}(EC)
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PANTHER Classification

PANTHER Family:	CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE (PTHR13693)
PANTHER Subfamily:	2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL (PTHR13693:SF102)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	transaminase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	acyltransferase activity, pyridoxal phosphate binding, catalytic activity, metal ion binding, glycine C-acetyltransferase activity, ligase activity
GO BP Complete:	L-threonine catabolic process to glycine, biosynthetic process, threonine catabolic process
GO CC Complete:	cytoplasm, cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=397\|UniProtKB=P22557	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000043518.1\|UniProtKB=A0A2I3SJ87	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000002057.3\|UniProtKB=G3QI29	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000008429.4\|UniProtKB=F6VBC4	Macaca mulatta	O
MOUSE\|MGI=MGI=87990\|UniProtKB=P08680	Mus musculus	O
RAT\|RGD=2084\|UniProtKB=Q63147	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000013178\|UniProtKB=Q3ZC31	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000012347.6\|UniProtKB=F1RUD4	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000000068.4\|UniProtKB=A0A5F5PQU3	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000000908.6\|UniProtKB=M3VVM0	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845030308.1\|UniProtKB=A0A8I3QB56	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000005320.4\|UniProtKB=F7G8E6	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000000687.4\|UniProtKB=F6PMU0	Ornithorhynchus anatinus	O
CHICK\|Gene=ALAS2\|UniProtKB=P18080	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000011090.4\|UniProtKB=G1KKY7	Anolis carolinensis	O
XENLA\|Gene=alas2.L\|UniProtKB=Q68F30	Xenopus laevis	O
XENLA\|Gene=alas2.S\|UniProtKB=A0A1L8F1K9	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-487573\|UniProtKB=A0A803KIW4	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000004707.2\|UniProtKB=A0A3B3HRQ7	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-001229-1\|UniProtKB=Q9YHT4	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000014541.1\|UniProtKB=W5NB93	lepisosteus oculatus	O
HUMAN\|HGNC=396\|UniProtKB=P13196	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000014991.5\|UniProtKB=H2QMR0	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000013205.3\|UniProtKB=G3RM14	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000005596.4\|UniProtKB=F7H7H8	Macaca mulatta	O
MOUSE\|MGI=MGI=87989\|UniProtKB=Q8VC19	Mus musculus	O
RAT\|RGD=68392\|UniProtKB=P13195	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000004118.6\|UniProtKB=A0A452DI36	Bos taurus	O
BOVIN\|Gene=ALAS1\|UniProtKB=A6QLI6	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000011437.5\|UniProtKB=F1SIX5	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000014533.3\|UniProtKB=F7C6J5	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000015705.6\|UniProtKB=M3WN44	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845030692.1\|UniProtKB=A0A8I3SCS4	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000011675.4\|UniProtKB=F7GEE8	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000014853.4\|UniProtKB=F7BXN4	Ornithorhynchus anatinus	O
CHICK\|Gene=ALAS1\|UniProtKB=P07997	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010027410.1\|UniProtKB=A0A1D5P0L4	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000006743.4\|UniProtKB=G1KFQ1	Anolis carolinensis	O
XENLA\|Gene=alas1.S\|UniProtKB=Q6DKE7	Xenopus laevis	O
XENLA\|Gene=alas1.L\|UniProtKB=Q6PAZ6	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-975179\|UniProtKB=Q66JC7	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000004789.2\|UniProtKB=H2LJ45	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-001229-2\|UniProtKB=Q7T2F0	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000007826.1\|UniProtKB=W5MM93	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000013810.1\|UniProtKB=W5N8S2	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000018918.1\|UniProtKB=H2XYE1	Ciona intestinalis	O
BRAFL\|Gene=LOC118415343\|UniProtKB=A0A9J7MQP3	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC588142\|UniProtKB=A0A7M7PV64	Strongylocentrotus purpuratus	O
DROME\|FlyBase=FBgn0020764\|UniProtKB=O18680	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP003184\|UniProtKB=Q7QBG3	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC013340\|UniProtKB=D6WM57	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_225386\|UniProtKB=E9GPQ8	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_320395\|UniProtKB=E9GPQ9	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW020754\|UniProtKB=B7PXN7	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG189320\|UniProtKB=T1FQY3	helobdella robusta	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g90289\|UniProtKB=A7RQQ4	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG55298\|UniProtKB=B3RUI1	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_38536\|UniProtKB=A9V8K7	Monosiga brevicollis	O
YEAST\|SGD=S000002640\|UniProtKB=P09950	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ABL104C\|UniProtKB=Q75DX7	Eremothecium gossypii	O
CANAL\|CGD=CAL0000189686\|UniProtKB=O94069	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_C06083g\|UniProtKB=Q6CCW0	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_02284\|UniProtKB=P38092	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_5G06270\|UniProtKB=Q4WTV8	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU06189\|UniProtKB=Q7RVY5	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_06936\|UniProtKB=A7ENN7	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_09357\|UniProtKB=F5H9G7	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC2F3.09\|UniProtKB=O14092	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_00097\|UniProtKB=B6JUZ8	Schizosaccharomyces japonicus	O
SCHJY\|EnsemblGenome=SJAG_03961\|UniProtKB=B6K5I7	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNB04260\|UniProtKB=Q5KLS2	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_05059\|UniProtKB=A0A0D1CK01	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_16892\|UniProtKB=E3L3M2	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_34735\|UniProtKB=F4NZF8	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0280763\|UniProtKB=Q54UX3	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_47154\|UniProtKB=F0ZHZ2	Dictyostelium purpureum	O
PLAF7\|EnsemblGenome=PF3D7_1246100\|UniProtKB=Q8I4X1	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00006265001\|UniProtKB=A0C4P9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00009596001\|UniProtKB=A0CR64	Paramecium tetraurelia	O
PHYRM\|Gene=H3G5K2_PHYRM\|UniProtKB=H3G5K2	Phytophthora ramorum	O
SELML\|EnsemblGenome=SELMODRAFT_407822\|UniProtKB=D8R4V5	Selaginella moellendorffii	O
HUMAN\|HGNC=4188\|UniProtKB=O75600	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000014348.6\|UniProtKB=H2R6Z4	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000043313.1\|UniProtKB=A0A2I2ZJZ0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000015258.4\|UniProtKB=A0A1D5QIB5	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1349389\|UniProtKB=O88986	Mus musculus	LDO
RAT\|RGD=1307291\|UniProtKB=A0A0G2K2Q2	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000008434.6\|UniProtKB=A0A3Q1M4U0	Bos taurus	O
BOVIN\|Gene=GCAT\|UniProtKB=Q0P5L8	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000029945.4\|UniProtKB=A0A5G2R5L3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000029050.3\|UniProtKB=A0A5F5Q043	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000037709.2\|UniProtKB=A0A9L0SYX3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000004278.5\|UniProtKB=M3W1W9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845005659.1\|UniProtKB=A0A8I3NC77	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000019074.4\|UniProtKB=H9H7A1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000049584.1\|UniProtKB=A0A6I8P1R5	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010010776.1\|UniProtKB=A0A8V0YA85	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000015453.4\|UniProtKB=G1KR54	Anolis carolinensis	LDO
XENLA\|Gene=gcat.L\|UniProtKB=A0A1L8GNV9	Xenopus laevis	O
XENLA\|Gene=gcat.S\|UniProtKB=Q801S5	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-984769\|UniProtKB=Q6P313	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000010542.2\|UniProtKB=H2M454	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-060518-3\|UniProtKB=F6P2R4	Danio rerio	LDO
CIOIN\|Ensembl=ENSCING00000011811.2\|UniProtKB=F6Y4G4	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118429177\|UniProtKB=A0A9J7MAA6	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC583773\|UniProtKB=A0A7M7PE13	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00012007\|UniProtKB=Q22768	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG17650\|UniProtKB=A8XRL9	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00118925\|UniProtKB=A0A2A6CMB3	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0036208\|UniProtKB=Q9VTN9	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP005781\|UniProtKB=Q7Q6L2	Anopheles gambiae	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_302058\|UniProtKB=E9GBC7	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW015295\|UniProtKB=B7QMM1	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG185935\|UniProtKB=T1FNG5	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g113623\|UniProtKB=A7SCT4	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG19375\|UniProtKB=B3RKQ9	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_10030\|UniProtKB=A9V4Z6	Monosiga brevicollis	LDO
TRYB2\|Gene_ORFName=Tb927.8.6060\|UniProtKB=Q57YK7	Trypanosoma brucei	LDO
PHYRM\|Gene=H3GAT3_PHYRM\|UniProtKB=H3GAT3	Phytophthora ramorum	LDO
KLENI\|Gene_ORFName=KFL_003300030\|UniProtKB=A0A1Y1I813	Klebsormidium nitens	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g231555\|UniProtKB=A7T9V2	Nematostella vectensis	O
PARTE\|EnsemblGenome=GSPATT00008339001\|UniProtKB=A0CM43	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00027895001\|UniProtKB=A0BE95	Paramecium tetraurelia	O
STRCO\|Gene_OrderedLocusName=SCO6800\|UniProtKB=Q9L232	Streptomyces coelicolor	LDO
BACTN\|EnsemblGenome=BT_1371\|UniProtKB=Q8A803	Bacteroides thetaiotaomicron	LDO
COXBU\|EnsemblGenome=CBU_0111\|UniProtKB=Q83F40	Coxiella burnetii	LDO
SHEON\|Gene_OrderedLocusName=SO_4674\|UniProtKB=Q8E8J0	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_A0886\|UniProtKB=Q9KL61	Vibrio cholerae	LDO
XANCP\|EnsemblGenome=XCC0939\|UniProtKB=Q8PC15	Xanthomonas campestris	LDO
SALTY\|EnsemblGenome=STM3709\|UniProtKB=P37419	Salmonella typhimurium	LDO
YERPE\|Gene_OrderedLocusName=YPO0059\|UniProtKB=A0A5P8YLN8	Yersinia pestis	LDO