PANTHER Gene Information

Gene Symbol(s):

MCM3

Organism:

Entamoeba histolytica

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Tree

Gene Name:

DNA replication licensing factor MCM3

Gene ID:

CL6EHI_103600

Protein ID:

Q24849

Persistent Id:

PTN000179787

Alternate Ids:

3407679(GeneID)	C4LVK4(AltAccession)
EhMCM3 {ECO:0000303\|PubMed:9297702}(Synonym)	rna_EHI_103600-1(Ensembl_PRO)
rna_EHI_103600-1(Ensembl_TRS)	MCM3{ECO:0000303\|PubMed:9297702}(Symbol)
DS571158(EMBL)	CAA66661(EMBL-CDS)
56470316(GI)	CL6EHI_103600(Ensembl)
XM_648280(refSeq)	3.6.4.12 {ECO:0000250\|UniProtKB:P25205}(EC)
MCM3_ENTH1(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER (PTHR11630)
PANTHER Subfamily:	DNA REPLICATION LICENSING FACTOR MCM3-RELATED (PTHR11630:SF46)
PANTHER GO-slim Molecular Function:	single-stranded DNA helicase activity single-stranded DNA binding
PANTHER GO-slim Biological Process:	DNA strand elongation involved in DNA replication mitotic DNA replication initiation double-strand break repair via break-induced replication
PANTHER GO-slim Cellular Component:	nucleus MCM complex
PANTHER protein class:	DNA metabolism protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ATP hydrolysis activity, double-stranded DNA helicase activity, helicase activity, four-way junction helicase activity, forked DNA-dependent helicase activity, cohesin loader activity, single-stranded DNA binding, DNA binding, ATP binding, DNA clamp loader activity, ATP-dependent H2AZ histone chaperone activity, ATP-dependent H3-H4 histone complex chaperone activity, single-stranded 3'-5' DNA helicase activity, single-stranded DNA helicase activity, chromatin extrusion motor activity, hydrolase activity
GO BP Complete:	DNA replication initiation, chromatin remodeling, double-strand break repair via break-induced replication, DNA replication, DNA strand elongation involved in DNA replication, DNA duplex unwinding, mitotic DNA replication initiation, chromatin looping
GO CC Complete:	nucleus, chromosome, chromatin, MCM complex, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
XENLA\|Gene=mmcm3\|UniProtKB=P49739	Xenopus laevis	O
DANRE\|ZFIN=ZDB-GENE-040121-2\|UniProtKB=B8JKC1	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000012167.1\|UniProtKB=W5N2V7	lepisosteus oculatus	O
HUMAN\|HGNC=6945\|UniProtKB=P25205	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000018275.7\|UniProtKB=A0A2J8P0X9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000005009.3\|UniProtKB=G3QQN9	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000021149.4\|UniProtKB=A0A1D5Q7N2	Macaca mulatta	LDO
MOUSE\|MGI=MGI=101845\|UniProtKB=P25206	Mus musculus	LDO
RAT\|RGD=1305168\|UniProtKB=D3ZFP4	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000010721\|UniProtKB=A4FUD9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000025488.4\|UniProtKB=I3L7E5	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000020506.3\|UniProtKB=F6VAG4	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000026755.4\|UniProtKB=M3X046	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845008858.1\|UniProtKB=A0A8I3N9W3	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000018822.4\|UniProtKB=F6YYR3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000039131.1\|UniProtKB=A0A6I8NWH0	Ornithorhynchus anatinus	LDO
CHICK\|Gene_ORFName=RCJMB04_1j4\|UniProtKB=Q5ZMN2	Gallus gallus	LDO
CHICK\|Ensembl=ENSGALG00010007916.1\|UniProtKB=F1NFJ0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000005146.4\|UniProtKB=G1KDS7	Anolis carolinensis	LDO
XENLA\|Gene=zmcm3\|UniProtKB=Q7ZXZ0	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-971646\|UniProtKB=Q28BS0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000016187.2\|UniProtKB=H2MNF6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-020419-4\|UniProtKB=Q5RIC5	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000015961.1\|UniProtKB=W5NG96	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000001519.3\|UniProtKB=F6Z4G6	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118404519\|UniProtKB=A0A9J7HJK2	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC589928\|UniProtKB=A0A7M7N293	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00003155\|UniProtKB=Q9XVR7	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00032682\|UniProtKB=A8XDJ5	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00271901\|UniProtKB=A0A2A6C5G6	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0002709\|UniProtKB=Q0KHR4	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0284442\|UniProtKB=Q9XYU1	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP001135\|UniProtKB=Q7PWZ5	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC002088\|UniProtKB=D7EIV8	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_305021\|UniProtKB=E9GN29	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW023354\|UniProtKB=B7QL56	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG94361\|UniProtKB=T1G905	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g215383\|UniProtKB=A7SPE9	Nematostella vectensis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g147748\|UniProtKB=A7T6D7	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG50536\|UniProtKB=B3S1I2	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_38861\|UniProtKB=A9VAL6	Monosiga brevicollis	LDO
YEAST\|SGD=S000000758\|UniProtKB=P24279	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFR355C\|UniProtKB=Q753F9	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000199452\|UniProtKB=A0A1D8PHW4	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F21945g\|UniProtKB=Q6C0T3	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_10497\|UniProtKB=C8V5J4	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G03920\|UniProtKB=Q4WK28	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU08009\|UniProtKB=Q7SAN2	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_13330\|UniProtKB=A7F6V0	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_06041\|UniProtKB=Q0UQC3	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPCC1682.02c\|UniProtKB=P30666	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_01762\|UniProtKB=B6JYU2	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNA00900\|UniProtKB=Q5KQ07	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_01679\|UniProtKB=A0A0D1CVV6	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_00361\|UniProtKB=E3JQQ5	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_11933\|UniProtKB=F4P537	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0280309\|UniProtKB=Q54VI9	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_157902\|UniProtKB=F1A0B0	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_33_2700\|UniProtKB=Q4Q3R6	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.2.3930\|UniProtKB=Q586W7	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_16214\|UniProtKB=A8BNN6	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_111580\|UniProtKB=A2F017	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_0527000\|UniProtKB=Q8I3J5	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00013517001\|UniProtKB=A0D4V3	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00016796001\|UniProtKB=A0DH93	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_34975\|UniProtKB=B8C546	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GAS2_PHYRM\|UniProtKB=H3GAS2	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_06g295700v5\|UniProtKB=A0A2K3DQK9	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00003p00257050\|UniProtKB=W1P0N2	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_78G00510\|UniProtKB=A0A0K9NNU1	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma08_g26580\|UniProtKB=A0A804KB25	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_021313mg\|UniProtKB=K3Z445	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3006G087500\|UniProtKB=A0A1B6PL07	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb351990\|UniProtKB=K7V0Q3	Zea mays	O
SORBI\|EnsemblGenome=SORBI_3009G172950\|UniProtKB=A0A1Z5R420	Sorghum bicolor	LDO
MAIZE\|Gene=ROA1\|UniProtKB=Q43704	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb290510\|UniProtKB=Q9SX04	Zea mays	LDO
MAIZE\|Gene=ROA3\|UniProtKB=Q9SX03	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os05g0476200\|UniProtKB=Q0DHC4	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_2g22360v3\|UniProtKB=I1HIG0	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0071300\|UniProtKB=F2DXJ7	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS1B02G309300\|UniProtKB=A0A3B5Z0N4	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS1A02G299500\|UniProtKB=A0A3B5Y323	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS1D02G298400\|UniProtKB=A0A3B5ZZ25	Triticum aestivum	LDO
NELNU\|Gene=LOC104585945\|UniProtKB=A0A1U7YU51	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110776605\|UniProtKB=A0A9R0HVY0	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr04g0179821\|UniProtKB=A0A251V1V5	Helianthus annuus	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a001621mg\|UniProtKB=A0A022RTD6	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_05201\|UniProtKB=A0A1U8FUX5	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400008308\|UniProtKB=M1AF36	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc02g070780.3\|UniProtKB=A0A3Q7F3W7	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107805042\|UniProtKB=A0A1S4B6M9	Nicotiana tabacum	O
TOBAC\|Gene=LOC107784237\|UniProtKB=A0A1S3Z8X9	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi10g00754\|UniProtKB=D7TK30	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_E02391\|UniProtKB=A0A059C6G4	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_A06P46030.1\|UniProtKB=A0A078H6H0	Brassica napus	O
BRACM\|EnsemblGenome=Bra025026\|UniProtKB=M4E8C0	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_A02P29810.1\|UniProtKB=A0A078I2C4	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra022027\|UniProtKB=M4DZT0	Brassica campestris	LDO
ARATH\|TAIR=locus=2170418\|UniProtKB=Q9FL33	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107935920\|UniProtKB=A0A1U8MEQ8	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107942638\|UniProtKB=A0A1U8MYF7	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107913776\|UniProtKB=A0A1U8KB76	Gossypium hirsutum	O
GOSHI\|Gene=LOC107905873\|UniProtKB=A0A1U8JCU6	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_029512\|UniProtKB=A0A061GEA4	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g004502mg\|UniProtKB=A0A067GEU2	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_004G131600v3\|UniProtKB=A0A2K2ATY3	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_15G120100\|UniProtKB=A0A2C9UG82	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_17G068400\|UniProtKB=A0A2C9U6P1	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0633290\|UniProtKB=B9S137	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_08G084400\|UniProtKB=I1KRF9	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_05G129700\|UniProtKB=I1K328	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_4g096700\|UniProtKB=G7JDY9	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr04_10910\|UniProtKB=A0A2I4EJP1	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_6G522780\|UniProtKB=A0A0A0KI30	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_4G078300\|UniProtKB=A0A251PHA3	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_100484\|UniProtKB=D8RSF5	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_404600\|UniProtKB=D8QVU6	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_90198\|UniProtKB=D8RD98	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c20_6190\|UniProtKB=A0A2K1IU91	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0001s0105\|UniProtKB=A0A2R6XVB2	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_007880010\|UniProtKB=A0A1Y1IKS5	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_0242\|UniProtKB=A9A310	Nitrosopumilus maritimus	O
KORCO\|EnsemblGenome=Kcr_1352\|UniProtKB=B1L6L9	Korarchaeum cryptofilum	O
SACS2\|EnsemblGenome=SSO0774\|UniProtKB=Q9UXG1	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE0901\|UniProtKB=Q8ZY88	Pyrobaculum aerophilum	O
METAC\|EnsemblGenome=MA_3829\|UniProtKB=Q8TJF6	Methanosarcina acetivorans	O
METAC\|EnsemblGenome=MA_0681\|UniProtKB=Q8TSW4	Methanosarcina acetivorans	O
METJA\|EnsemblGenome=MJ_ECL13\|UniProtKB=Q60275	Methanocaldococcus jannaschii	O
METJA\|EnsemblGenome=MJ_1489\|UniProtKB=Q58884	Methanocaldococcus jannaschii	O
METJA\|EnsemblGenome=MJ_0363\|UniProtKB=Q57809	Methanocaldococcus jannaschii	O
METJA\|EnsemblGenome=MJ_0961\|UniProtKB=Q58371	Methanocaldococcus jannaschii	O
HALSA\|EnsemblGenome=VNG_2181G\|UniProtKB=Q9HNA5	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK1361\|UniProtKB=Q5JGW1	Thermococcus kodakaraensis	O
THEKO\|EnsemblGenome=TK0096\|UniProtKB=Q5JEJ0	Thermococcus kodakaraensis	O
THEKO\|EnsemblGenome=TK1620\|UniProtKB=Q5JIT1	Thermococcus kodakaraensis	O