PANTHER Gene Information

Gene Symbol(s):

HPN

Organism:

Felis catus

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Gene Name:

Hepsin

Gene ID:

ENSFCAG00000008882.6

Protein ID:

A0A2I2UDC4

Persistent Id:

PTN001956848

Alternate Ids:

A0A2I2UDC4_FELCA(UniProtKB-ID)	AANG04004572(EMBL)
ENSFCAT00000047920(Ensembl_TRS)	ENSFCAP00000030497(Ensembl_PRO)
A0A2I2UDC4(Synonym)	ENSFCAG00000008882(Ensembl)
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PANTHER Classification

PANTHER Family:	TRANSMEMBRANE PROTEASE SERINE (PTHR24253)
PANTHER Subfamily:	SERINE PROTEASE HEPSIN (PTHR24253:SF166)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	serine protease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	serine-type endopeptidase activity, serine-type peptidase activity, peptidase activity, serine-type exopeptidase activity
GO BP Complete:	regulation of cell shape, positive regulation by host of viral transcription, positive regulation of cell growth, negative regulation of epithelial to mesenchymal transition, negative regulation of apoptotic process, proteolysis, negative regulation of epithelial cell proliferation, positive regulation of plasminogen activation, basement membrane disassembly, positive regulation of hepatocyte proliferation
GO CC Complete:	endoplasmic reticulum membrane, nuclear membrane, membrane, plasma membrane, cell surface

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=5155\|UniProtKB=P05981	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000010826.6\|UniProtKB=A0A2J8QH94	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000005066.3\|UniProtKB=A0A2I2ZEG1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000004844.4\|UniProtKB=F6XEI3	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1196620\|UniProtKB=O35453	Mus musculus	LDO
RAT\|RGD=61982\|UniProtKB=Q05511	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000003829.5\|UniProtKB=A1L5C6	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000021867.4\|UniProtKB=I3L6R5	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000009817.4\|UniProtKB=A0A9L0RLQ1	Equus caballus	LDO
CANLF\|Ensembl=ENSCAFG00845003738.1\|UniProtKB=A0A8I3MSC1	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000013734.4\|UniProtKB=F6XQG8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000047331.1\|UniProtKB=A0A6I8N3E7	Ornithorhynchus anatinus	LDO
XENLA\|Gene=LOC108705714\|UniProtKB=A0A8J1LAS1	Xenopus laevis	O
XENLA\|Gene=hpn.S\|UniProtKB=A0A8J1LDQ2	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-995348\|UniProtKB=A0A6I8RUX2	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000006062.2\|UniProtKB=H2LNJ0	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-141212-373\|UniProtKB=A5D6S2	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000003452.1\|UniProtKB=W5M6U1	lepisosteus oculatus	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_277744\|UniProtKB=C3Y020	Branchiostoma floridae	LDO
BRAFL\|Gene=LOC118412026\|UniProtKB=A0A9J7KU28	Branchiostoma floridae	O
BRAFL\|Gene=LOC118420239\|UniProtKB=A0A9J7LHA4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118431979\|UniProtKB=A0A9J7MEK2	Branchiostoma floridae	O
DROME\|FlyBase=FBgn0052755\|UniProtKB=Q8IRR3	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP028031\|UniProtKB=A0A1S4HDU6	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP006087\|UniProtKB=A0A1S4GR69	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC006026\|UniProtKB=D6WUI3	Tribolium castaneum	LDO
HELRO\|EnsemblGenome=HelroG193530\|UniProtKB=T1FV33	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g198217\|UniProtKB=A7RJY0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g127465\|UniProtKB=A7SQF1	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g111870\|UniProtKB=A7SB63	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g130234\|UniProtKB=A7SSR9	Nematostella vectensis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g109826\|UniProtKB=A7S9G1	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g230861\|UniProtKB=A7SSS0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g41116\|UniProtKB=A7SZI9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g109239\|UniProtKB=A7S8Y5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g88458\|UniProtKB=A7RP61	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g124644\|UniProtKB=A7SNB8	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG61839\|UniProtKB=B3SC39	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG25686\|UniProtKB=B3RY71	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG53235\|UniProtKB=B3RNP0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG18710\|UniProtKB=B3RIF5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG5625\|UniProtKB=B3RYJ8	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG26286\|UniProtKB=B3RZF9	Trichoplax adhaerens	LDO