PANTHER Gene Information   
Gene Symbol(s): KDR
Organism: Felis catus
View Gene in Tree
Tree
Tree
Gene Name: receptor protein-tyrosine kinase
Gene ID: ENSFCAG00000009679.6
Protein ID: M3WBW2
Persistent Id: PTN001974995
Alternate Ids:
ENSFCAT00000009683(Ensembl_TRS) M3WBW2_FELCA(UniProtKB-ID)
AANG04001605(EMBL) M3WBW2(Synonym)
ENSFCAP00000008977(Ensembl_PRO) ENSFCAG00000009679(Ensembl)
Show All

PANTHER Classification
PANTHER Family: TYROSINE-PROTEIN KINASE RECEPTOR (PTHR24416)
PANTHER Subfamily: VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (PTHR24416:SF45)  
PANTHER GO-slim Molecular Function: growth factor binding
transmembrane receptor protein tyrosine kinase activity
PANTHER GO-slim Biological Process: transmembrane receptor protein tyrosine kinase signaling pathway
positive regulation of developmental process
positive regulation of kinase activity
cell migration
angiogenesis
positive regulation of multicellular organismal process
positive regulation of cell migration
endothelial cell differentiation
regulation of angiogenesis
regulation of MAPK cascade
PANTHER GO-slim Cellular Component: receptor complex
plasma membrane
PANTHER protein class: transmembrane signal receptor
Pathway Categories: Angiogenesis
   Vascular Endothelial Growth Factor Receptor-2
VEGF signaling pathway
   Vascular Endothelial Growth Factor Receptor-2
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: placental growth factor receptor activity, growth factor binding, macrophage colony-stimulating factor receptor activity, insulin-like growth factor receptor activity, integrin binding, boss receptor activity, hepatocyte growth factor receptor activity, fibroblast growth factor receptor activity, ATP binding, protein tyrosine kinase activity, insulin receptor activity, cadherin binding, coreceptor activity, identical protein binding, stem cell factor receptor activity, brain-derived neurotrophic factor receptor activity, protein tyrosine kinase collagen receptor activity, vascular endothelial growth factor receptor activity, vascular endothelial growth factor binding, GPI-linked ephrin receptor activity, epidermal growth factor receptor activity, transmembrane-ephrin receptor activity, platelet-derived growth factor beta-receptor activity, platelet-derived growth factor alpha-receptor activity, metal ion binding
GO BP Complete: embryonic hemopoiesis, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, endothelial cell differentiation, cell migration involved in sprouting angiogenesis, branching morphogenesis of an epithelial tube, positive regulation of cell migration involved in sprouting angiogenesis, positive regulation of angiogenesis, lung alveolus development, epithelial cell proliferation, lymph vessel development, negative regulation of endothelial cell apoptotic process, vascular endothelial growth factor receptor-2 signaling pathway, positive regulation of epithelial cell proliferation, Kit signaling pathway, regulation of bone development, positive regulation of macroautophagy, vascular endothelial growth factor receptor-1 signaling pathway, vascular wound healing, platelet-derived growth factor receptor-alpha signaling pathway, macrophage colony-stimulating factor signaling pathway, platelet-derived growth factor receptor-beta signaling pathway, positive regulation of positive chemotaxis, insulin-like growth factor receptor signaling pathway, positive regulation of mesenchymal cell proliferation, collagen-activated tyrosine kinase receptor signaling pathway, positive regulation of mitochondrial fission, hepatocyte growth factor receptor signaling pathway, negative regulation of gene expression, brain-derived neurotrophic factor receptor signaling pathway, vascular endothelial growth factor receptor signaling pathway, positive regulation of focal adhesion assembly, blood vessel endothelial cell differentiation, positive regulation of stem cell proliferation, ephrin receptor signaling pathway, positive regulation of vasculogenesis, mesenchymal cell proliferation, positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction, positive regulation of cell migration, semaphorin-plexin signaling pathway, regulation of cell shape, regulation of MAPK cascade, calcium ion homeostasis, multicellular organism development, insulin receptor signaling pathway, hemopoiesis, positive regulation of cell population proliferation, vasculogenesis, endocardium development, surfactant homeostasis, endothelium development, negative regulation of neuron apoptotic process, angiogenesis, branching involved in blood vessel morphogenesis, stem cell proliferation, positive regulation of endothelial cell chemotaxis, positive regulation of mitochondrial depolarization, positive regulation of endothelial cell migration, cell migration, lung development, cellular response to hydrogen sulfide, epithelial cell maturation, vascular endothelial growth factor signaling pathway, regulation of hematopoietic progenitor cell differentiation, cell surface receptor protein tyrosine kinase signaling pathway, positive regulation of MAPK cascade, positive regulation of blood vessel endothelial cell migration, ovarian follicle development, positive regulation of BMP signaling pathway, post-embryonic camera-type eye morphogenesis, cell fate commitment, positive regulation of ERK1 and ERK2 cascade, cell differentiation, positive regulation of endothelial cell proliferation, cellular response to vascular endothelial growth factor stimulus
GO CC Complete: external side of plasma membrane, endoplasmic reticulum, Golgi apparatus, receptor complex, plasma membrane, cell surface, nucleus, early endosome, sorting endosome, endosome, anchoring junction, cytoplasm, membrane, membrane raft, cell junction, cell periphery
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: -

Orthologs