PANTHER Gene Information

Gene Symbol(s):

TDG

Organism:

Felis catus

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Gene Name:

Thymine DNA glycosylase

Gene ID:

ENSFCAG00000014079.6

Protein ID:

A0A337RVL7

Persistent Id:

PTN001741766

Alternate Ids:

A0A337RVL7_FELCA(UniProtKB-ID)	ENSFCAG00000014079(Ensembl)
A0A337RVL7(Synonym)	ENSFCAT00000066638(Ensembl_TRS)
ENSFCAP00000041060(Ensembl_PRO)	AANG04003655(EMBL)
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PANTHER Classification

PANTHER Family:	G/T AND G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE (PTHR12159)
PANTHER Subfamily:	G_T MISMATCH-SPECIFIC THYMINE DNA GLYCOSYLASE (PTHR12159:SF9)
PANTHER GO-slim Molecular Function:	DNA N-glycosylase activity
PANTHER GO-slim Biological Process:	base-excision repair
PANTHER GO-slim Cellular Component:
PANTHER protein class:	DNA glycosylase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	SUMO binding, G/U mismatch-specific uracil-DNA glycosylase activity, pyrimidine-specific mismatch base pair DNA N-glycosylase activity, double-stranded DNA binding, mismatch base pair DNA N-glycosylase activity, magnesium ion binding, ATP binding, chloride ion binding, uracil DNA N-glycosylase activity, DNA N-glycosylase activity, mismatched DNA binding, sodium ion binding, hydrolase activity
GO BP Complete:	DNA repair, base-excision repair, base-excision repair, AP site formation
GO CC Complete:	nucleus, plasma membrane, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11700\|UniProtKB=Q13569	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000042053.2\|UniProtKB=A0A2I3TRI1	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000052766.1\|UniProtKB=K6ZC87	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000026044.2\|UniProtKB=G3RSZ8	Gorilla gorilla gorilla	O
GORGO\|Ensembl=ENSGGOG00000015648.3\|UniProtKB=A0A2I2ZKP6	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000021291.4\|UniProtKB=F6V7N0	Macaca mulatta	LDO
MOUSE\|MGI=MGI=108247\|UniProtKB=P56581	Mus musculus	LDO
RAT\|RGD=620959\|UniProtKB=A0A096MK32	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000021633.5\|UniProtKB=A4IF83	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000000847.5\|UniProtKB=F1SRK8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000002072.4\|UniProtKB=A0A9L0SUJ3	Equus caballus	LDO
CANLF\|Ensembl=ENSCAFG00845010683.1\|UniProtKB=A0A8I3RY56	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000002206.4\|UniProtKB=F7G3M8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000005552.3\|UniProtKB=A0A6I8NTK1	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010010085.1\|UniProtKB=Q9PUA4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000016148.4\|UniProtKB=R4GB76	Anolis carolinensis	LDO
XENLA\|Gene=tdg.S\|UniProtKB=Q6AZQ5	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1006128\|UniProtKB=Q6DIK5	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000029322.1\|UniProtKB=A0A3B3I5B3	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050522-44\|UniProtKB=Q503G3	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000001329.2\|UniProtKB=H2L735	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-131121-30\|UniProtKB=X1WBY3	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000015025.1\|UniProtKB=W5NCY6	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000020650.1\|UniProtKB=H2XQ41	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118403306\|UniProtKB=A0A9J7KDM8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC586471\|UniProtKB=A0A7M7LW15	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0026869\|UniProtKB=Q9V4D8	Drosophila melanogaster	LDO
TRICA\|EnsemblGenome=TC004290\|UniProtKB=D7EL51	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_43853\|UniProtKB=E9FZU9	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG124128\|UniProtKB=T1EH02	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG71611\|UniProtKB=T1G0P0	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g205250\|UniProtKB=A7S194	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG6342\|UniProtKB=B3RX98	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_29131\|UniProtKB=A9VA78	Monosiga brevicollis	LDO
CANAL\|CGD=CAL0000180470\|UniProtKB=A0A1D8PKI0	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F04796g\|UniProtKB=Q6C2V5	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_05479\|UniProtKB=Q5B1V1	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_6G13340\|UniProtKB=A4D9Q9	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU02098\|UniProtKB=Q7SDB2	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_05672\|UniProtKB=A7EK26	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_14120\|UniProtKB=Q0U1U9	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPCC965.05c\|UniProtKB=O59825	Schizosaccharomyces pombe	LDO
USTMA\|EnsemblGenome=UMAG_10845\|UniProtKB=A0A0D1DXJ6	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_07986\|UniProtKB=E3KBU2	Puccinia graminis	LDO
CHLRE\|EnsemblGenome=CHLRE_03g180100v5\|UniProtKB=A0A2K3DXQ7	Chlamydomonas reinhardtii	LDO
DEIRA\|EnsemblGenome=DR_0715\|UniProtKB=Q9RWF4	Deinococcus radiodurans	LDO
BRADU\|Gene=Q89FN8_BRADU\|UniProtKB=Q89FN8	Bradyrhizobium diazoefficiens	LDO
SALTY\|EnsemblGenome=STM3212\|UniProtKB=Q7CPR7	Salmonella typhimurium	LDO
ECOLI\|EnsemblGenome=BAE77119\|UniProtKB=P0A9H1	Escherichia coli	LDO