PANTHER Gene Information

Gene Symbol(s):

PACSIN1

Organism:

Felis catus

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Gene Name:

Protein kinase C and casein kinase substrate in neurons protein 1

Gene ID:

ENSFCAG00000015356.6

Protein ID:

M3WMG0

Persistent Id:

PTN001890860

Alternate Ids:

M3WMG0_FELCA(UniProtKB-ID)	1126423752(GI)
ENSFCAG00000015356(Ensembl)	XP_019686035(refSeq)
M3WMG0(Synonym)	AANG04003966(EMBL)
ENSFCAP00000014239(Ensembl_PRO)	ENSFCAT00000015359(Ensembl_TRS)
101095898(GeneID)
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PANTHER Classification

PANTHER Family:	PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 (PTHR23065)
PANTHER Subfamily:	PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 1 (PTHR23065:SF16)
PANTHER GO-slim Molecular Function:	phospholipid binding
PANTHER GO-slim Biological Process:	regulation of dendrite development positive regulation of cellular component organization plasma membrane organization positive regulation of developmental process cytoskeleton organization neuron projection morphogenesis regulation of endocytosis
PANTHER GO-slim Cellular Component:	plasma membrane endosome
PANTHER protein class:	actin or actin-binding cytoskeletal protein

Pathway Categories:

Huntington disease

Protein kinase C and casein kinase substrate in neurons 1

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	identical protein binding, lipid binding, phospholipid binding, cytoskeletal protein binding
GO BP Complete:	plasma membrane tubulation, negative regulation of endocytosis, cytoskeleton organization, synaptic vesicle endocytosis, neuron projection morphogenesis, protein localization to membrane, actin filament organization, regulation of endocytosis, neuron development, positive regulation of dendrite development
GO CC Complete:	cytoplasmic vesicle membrane, endosome, photoreceptor ribbon synapse, cytoplasm, presynaptic endocytic zone, cytosol, cytoplasmic vesicle, ruffle membrane, synapse, neuron projection, plasma membrane, COPI-coated vesicle

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=8570\|UniProtKB=Q9BY11	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000018064.4\|UniProtKB=A0A2J8NYV8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000023013.2\|UniProtKB=G3RRV4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000007811.4\|UniProtKB=G7MRS0	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1345181\|UniProtKB=Q61644	Mus musculus	LDO
RAT\|RGD=3247\|UniProtKB=Q9Z0W5	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000016124\|UniProtKB=A7MBI0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000027053.4\|UniProtKB=A0A287AHG5	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000013077.4\|UniProtKB=A0A3Q2LBA6	Equus caballus	LDO
CANLF\|Ensembl=ENSCAFG00845026967.1\|UniProtKB=A0A8I3Q065	Canis lupus familiaris	LDO
ORNAN\|Ensembl=ENSOANG00000041042.1\|UniProtKB=A0A6I8PCJ7	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010026124.1\|UniProtKB=A0A8V1AAI8	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000015801.3\|UniProtKB=G1KRR6	Anolis carolinensis	LDO
XENLA\|Gene=pacsin1.S\|UniProtKB=Q6AX65	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-494779\|UniProtKB=A0A6I8QHL6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000013207.2\|UniProtKB=A0A3B3IFS6	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050522-155\|UniProtKB=A0A2R9YJM4	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000007282.2\|UniProtKB=H2LSR5	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050913-35\|UniProtKB=Q4V920	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000009969.1\|UniProtKB=W5MUY1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000008003.3\|UniProtKB=A0A1W2WFB7	Ciona intestinalis	O
BRAFL\|Gene=LOC118414577\|UniProtKB=A0A9J7L3V5	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC576050\|UniProtKB=A0A7M7LW56	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00018467\|UniProtKB=Q6AHQ8	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG16865\|UniProtKB=A8XPZ1	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00108383\|UniProtKB=A0A454Y2I0	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0053094\|UniProtKB=A0A0B4KH28	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP008046\|UniProtKB=A0A1S4GX35	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC007515\|UniProtKB=D2A3I3	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_303168\|UniProtKB=E9FT89	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW018948\|UniProtKB=B7PNV7	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG156856\|UniProtKB=T1EM19	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG97481\|UniProtKB=T1G9H0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG156082\|UniProtKB=T1ELR6	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g51540\|UniProtKB=A7S2R6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g229120\|UniProtKB=A7S0K6	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG50721\|UniProtKB=B3S5Q2	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_26556\|UniProtKB=A9V2Q3	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_26520\|UniProtKB=A9V2L9	Monosiga brevicollis	O
YEAST\|SGD=S000000626\|UniProtKB=P25623	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AEL147W\|UniProtKB=Q758D3	Eremothecium gossypii	O
CANAL\|CGD=CAL0000174492\|UniProtKB=A0A1D8PL12	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_F01694g\|UniProtKB=Q6C390	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_00697\|UniProtKB=C8VRP5	Emericella nidulans	O
NEUCR\|EnsemblGenome=NCU04427\|UniProtKB=Q7RZ47	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_07570\|UniProtKB=A7EQG8	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_02674\|UniProtKB=Q0UZZ0	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC4C3.06\|UniProtKB=O43059	Schizosaccharomyces pombe	O
USTMA\|EnsemblGenome=UMAG_02358\|UniProtKB=A0A0D1E1L9	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_10354\|UniProtKB=E3KKQ8	Puccinia graminis	O
YEAST\|SGD=S000001847\|UniProtKB=P43556	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ABR241C\|UniProtKB=Q75CY1	Eremothecium gossypii	O
CANAL\|CGD=CAL0000200127\|UniProtKB=A0A1D8PTF4	Candida albicans	O
CANAL\|CGD=CAL0000176620\|UniProtKB=A0A1D8PTI9	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_B15686g\|UniProtKB=Q6CEH0	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_E05489g\|UniProtKB=Q6C6X5	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_05677\|UniProtKB=Q5B1A3	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_7G04300\|UniProtKB=Q4WGA0	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU09537\|UniProtKB=Q7S2C4	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_03088\|UniProtKB=A7ECP9	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_03668\|UniProtKB=Q0UX46	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC1952.16\|UniProtKB=Q9UUJ3	Schizosaccharomyces pombe	O
SCHPO\|PomBase=SPAC13A11.01c\|UniProtKB=Q09697	Schizosaccharomyces pombe	O
CRYNJ\|EnsemblGenome=CNE01000\|UniProtKB=Q5KH74	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_10913\|UniProtKB=A0A0D1DWP4	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_11096\|UniProtKB=E3KND1	Puccinia graminis	O
YEAST\|SGD=S000004635\|UniProtKB=Q05080	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ABR082W\|UniProtKB=Q75DE5	Eremothecium gossypii	O
CANAL\|CGD=CAL0000193415\|UniProtKB=Q59UQ6	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_E29557g\|UniProtKB=Q6C455	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_04963\|UniProtKB=Q5B3B7	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_3G10250\|UniProtKB=Q4WXP7	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU10905\|UniProtKB=A7UWG5	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_06645\|UniProtKB=A7EMU6	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_08413\|UniProtKB=Q0UIK1	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC20G8.05c\|UniProtKB=Q09822	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_03596\|UniProtKB=B6K4N4	Schizosaccharomyces japonicus	O
SCHPO\|PomBase=SPBC11C11.02\|UniProtKB=Q10199	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_04077\|UniProtKB=B6K5V1	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNK00960\|UniProtKB=Q5K9S2	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNB00620\|UniProtKB=Q5KMS8	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_00168\|UniProtKB=A0A0D1EBL3	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_16937\|UniProtKB=E3L3F0	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_16936\|UniProtKB=E3L3E9	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_21447\|UniProtKB=H6QRG1	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_90049\|UniProtKB=F4P6T8	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_92106\|UniProtKB=F4PCY6	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_36867\|UniProtKB=F4P0Q6	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_33239\|UniProtKB=F4P3D9	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_110690\|UniProtKB=C4LUB6	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_065490\|UniProtKB=B1N368	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=EHI_105210\|UniProtKB=C4M126	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_148050\|UniProtKB=C4LSX5	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0274695\|UniProtKB=Q555L8	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_48387\|UniProtKB=F0ZNY9	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0290233\|UniProtKB=Q54GD0	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_155654\|UniProtKB=F0ZUK4	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0271676\|UniProtKB=Q75JD4	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_92017\|UniProtKB=F0ZKM3	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0271812\|UniProtKB=Q55AN3	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_152774\|UniProtKB=F0ZM88	Dictyostelium purpureum	O
PARTE\|EnsemblGenome=GSPATT00033091001\|UniProtKB=A0BXH1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000311001\|UniProtKB=A0BBF9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00025956001\|UniProtKB=A0EE94	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00019613001\|UniProtKB=A0DS92	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00003632001\|UniProtKB=A0E652	Paramecium tetraurelia	O
PARTE\|Gene_ORFName=PTMB.209\|UniProtKB=Q6BG14	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00021727001\|UniProtKB=A0DZU2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00036084001\|UniProtKB=A0C836	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00011037001\|UniProtKB=A0CVQ2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016341001\|UniProtKB=A0DEP8	Paramecium tetraurelia	O
PHYRM\|Gene=H3GW87_PHYRM\|UniProtKB=H3GW87	Phytophthora ramorum	O
PHYRM\|Gene=H3HBN7_PHYRM\|UniProtKB=H3HBN7	Phytophthora ramorum	O