PANTHER Gene Information

Gene Symbol(s):

PNKP

Organism:

Felis catus

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Gene Name:

Polynucleotide kinase 3'-phosphatase

Gene ID:

ENSFCAG00000018550.5

Protein ID:

A0A337SAT2

Persistent Id:

PTN001739623

Alternate Ids:

AANG04000747(EMBL)	ENSFCAG00000018550(Ensembl)
A0A337SAT2(Synonym)	ENSFCAT00000051550(Ensembl_TRS)
ENSFCAP00000043013(Ensembl_PRO)	A0A337SAT2_FELCA(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE (PTHR12083)
PANTHER Subfamily:	BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE (PTHR12083:SF9)
PANTHER GO-slim Molecular Function:	phosphatase activity phosphotransferase activity, alcohol group as acceptor kinase activity double-stranded DNA binding
PANTHER GO-slim Biological Process:	DNA repair
PANTHER GO-slim Cellular Component:
PANTHER protein class:	nucleotide phosphatase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	double-stranded DNA binding, polynucleotide 3'-phosphatase activity, ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity, hydrolase activity
GO BP Complete:	DNA ligation involved in DNA repair, DNA repair, response to oxidative stress, positive regulation of telomere capping, positive regulation of telomere maintenance via telomerase, double-strand break repair via nonhomologous end joining, positive regulation of double-strand break repair via nonhomologous end joining
GO CC Complete:	nucleus, site of double-strand break, nucleolus, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9154\|UniProtKB=Q96T60	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000011323.5\|UniProtKB=K7BAU7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010193.3\|UniProtKB=G3R3W6	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000011622.4\|UniProtKB=F6PK17	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1891698\|UniProtKB=Q9JLV6	Mus musculus	LDO
RAT\|RGD=1303331\|UniProtKB=A0A0G2JUH4	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000001834.5\|UniProtKB=F1N3Q9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000003195.5\|UniProtKB=A0A5G2QGK2	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000017461.4\|UniProtKB=A0A5F5Q2T5	Equus caballus	LDO
CANLF\|Ensembl=ENSCAFG00845020569.1\|UniProtKB=A0A8I3P973	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000013400.5\|UniProtKB=A0A5F8GRL3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000040153.1\|UniProtKB=A0A6I8P7U7	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000012743.4\|UniProtKB=G1KMT2	Anolis carolinensis	LDO
XENLA\|Gene=pnkp.S\|UniProtKB=A0A1L8FHD3	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5953796\|UniProtKB=A0A8J0SI24	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000015667.2\|UniProtKB=H2MLN4	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-061013-433\|UniProtKB=A0A0R4IRS4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000006597.1\|UniProtKB=W5MHX5	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006210.3\|UniProtKB=F6X0L7	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118418019\|UniProtKB=A0A9J7LC71	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC580136\|UniProtKB=A0A7M7N4V1	Strongylocentrotus purpuratus	LDO
PRIPA\|EnsemblGenome=WBGene00106864\|UniProtKB=A0A2A6CB59	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0037578\|UniProtKB=Q9VHS0	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP012174\|UniProtKB=A0A1S4H8L3	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC009034\|UniProtKB=D6WPR6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_46356\|UniProtKB=E9G6T6	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG109229\|UniProtKB=T1EER7	helobdella robusta	LDO
TRIAD\|EnsemblGenome=TriadG59893\|UniProtKB=B3S6Q9	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_6863\|UniProtKB=A9UUG9	Monosiga brevicollis	LDO
YEAST\|SGD=S000004765\|UniProtKB=Q03796	Saccharomyces cerevisiae	LDO
CANAL\|CGD=CAL0000186712\|UniProtKB=A0A1D8PGJ5	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E29051g\|UniProtKB=Q6C478	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_05751\|UniProtKB=Q5B129	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_6G06820\|UniProtKB=Q4WNC7	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU08151\|UniProtKB=Q7S497	Neurospora crassa	LDO
PHANO\|EnsemblGenome=SNOG_05363\|UniProtKB=Q0USA1	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC23C11.04c\|UniProtKB=O13911	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02680\|UniProtKB=B6K0W2	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNA07870\|UniProtKB=Q5KN35	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_02211\|UniProtKB=A0A0D1E5N4	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_20262\|UniProtKB=E3NXK9	Puccinia graminis	LDO
PUCGT\|EnsemblGenome=PGTG_18987\|UniProtKB=E3L8U9	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_89257\|UniProtKB=F4P527	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0281229\|UniProtKB=Q54U78	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_6215\|UniProtKB=F0ZYN5	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_23_0310\|UniProtKB=Q4QBE3	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_31_2130\|UniProtKB=Q4Q648	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.8.2250\|UniProtKB=Q57XG4	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb927.6.1580\|UniProtKB=Q585Q2	Trypanosoma brucei	LDO
PLAF7\|EnsemblGenome=PF3D7_0817400\|UniProtKB=C0H4V3	Plasmodium falciparum	LDO
PHYRM\|Gene=H3GMS2_PHYRM\|UniProtKB=H3GMS2	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_02g079150v5\|UniProtKB=A0A2K3E0F4	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_09g388726v5\|UniProtKB=A0A2K3DDZ0	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00075p00081460\|UniProtKB=W1P9H5	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_375G00160\|UniProtKB=A0A0K9P7V6	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma06_g22510\|UniProtKB=A0A804JJ76	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_001138mg\|UniProtKB=K3XGW7	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3003G288800\|UniProtKB=A0A1W0VZC1	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb153930\|UniProtKB=C0PDZ5	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os01g0737300\|UniProtKB=A0A0P0V7Y6	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_2g49175v3\|UniProtKB=A0A2K2DES1	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0287310\|UniProtKB=A0A8I6WTB1	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS3D02G279000\|UniProtKB=A0A3B6GV97	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3B02G312900\|UniProtKB=W5CUZ8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3A02G278700\|UniProtKB=A0A3B6EJ52	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_001472\|UniProtKB=A0A1U7ZRZ5	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110796091\|UniProtKB=A0A9R0IWG1	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HannXRQ_Chr12g0362951\|UniProtKB=A0A251T045	Helianthus annuus	LDO
HELAN\|Gene_ORFName=HanXRQr2_Chr12g0532581\|UniProtKB=A0A9K3HF56	Helianthus annuus	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr13g0569011\|UniProtKB=A0A251SP46	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C900496260\|UniProtKB=A0A9R1UIY7	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a007930mg\|UniProtKB=A0A022RYF3	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_20559\|UniProtKB=A0A1U8HCK7	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400007070\|UniProtKB=M1AA86	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc07g062430.3\|UniProtKB=A0A3Q7HE95	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107786424\|UniProtKB=A0A1S3ZGA2	Nicotiana tabacum	O
TOBAC\|Gene=LOC107816055\|UniProtKB=A0A1S4C8D1	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi19g00103\|UniProtKB=E0CS89	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_F01242\|UniProtKB=A0A059BN48	Eucalyptus grandis	LDO
BRACM\|EnsemblGenome=Bra027296\|UniProtKB=M4EET4	Brassica campestris	O
BRACM\|EnsemblGenome=Bra001572\|UniProtKB=M4CBJ2	Brassica campestris	LDO
ARATH\|TAIR=locus=2086355\|UniProtKB=Q84JE8	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107943057\|UniProtKB=A0A1U8N357	Gossypium hirsutum	O
GOSHI\|Gene=LOC107916715\|UniProtKB=A0A1U8KKR7	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_031850\|UniProtKB=A0A061F9D4	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g012119mg\|UniProtKB=A0A067E7V2	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_001G390500v3\|UniProtKB=A0A2K2CAP7	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_15G094900\|UniProtKB=A0A2C9UFJ3	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0105580\|UniProtKB=B9SEU6	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_06G229100\|UniProtKB=I1KDK7	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_12G157700\|UniProtKB=K7LUT0	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_6g466500\|UniProtKB=A0A072UAF5	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr02_20790\|UniProtKB=A0A2I4GZM2	Juglans regia	LDO
JUGRE\|EnsemblGenome=Jr02_20800\|UniProtKB=A0A2I4GZK8	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_4G627160\|UniProtKB=A0A0A0KZI4	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_4G164600\|UniProtKB=A0A251PLJ5	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_430656\|UniProtKB=D8TA31	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c6_17140\|UniProtKB=A0A2K1KG01	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0056s0069\|UniProtKB=A0A2R6WUV9	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000540220\|UniProtKB=A0A0U9HIH6	Klebsormidium nitens	LDO