PANTHER Gene Information

Gene Symbol(s):

NRDC

Organism:

Felis catus

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Gene Name:

Nardilysin convertase

Gene ID:

ENSFCAG00000022018.4

Protein ID:

A0A2I2U129

Persistent Id:

PTN001724394

Alternate Ids:

AANG04003279(EMBL)	A0A2I2U129(Synonym)
ENSFCAG00000022018(Ensembl)	ENSFCAP00000026157(Ensembl_PRO)
XM_006934739(refSeq)	586995535(GI)
101088678(GeneID)	ENSFCAT00000041926(Ensembl_TRS)
A0A2I2U129_FELCA(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	NARDILYSIN (PTHR43690)
PANTHER Subfamily:	INSULIN-DEGRADING ENZYME-RELATED (PTHR43690:SF18)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	metalloprotease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	metal ion binding, metalloendopeptidase activity, metallopeptidase activity
GO BP Complete:	positive regulation of membrane protein ectodomain proteolysis, proteolysis
GO CC Complete:	mitochondrial matrix

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=7995\|UniProtKB=O43847	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000000731.7\|UniProtKB=H2PZ07	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000004793.3\|UniProtKB=G3SK41	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000004738.4\|UniProtKB=H9FUZ3	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1201386\|UniProtKB=Q8BHG1	Mus musculus	LDO
RAT\|RGD=3210\|UniProtKB=P47245	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000021174.5\|UniProtKB=A0A3Q1LY70	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000003870.5\|UniProtKB=A0A287AAA2	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000021612.4\|UniProtKB=A0A9L0S5G7	Equus caballus	LDO
CANLF\|Ensembl=ENSCAFG00845021372.1\|UniProtKB=A0A8I3P8J4	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000000839.4\|UniProtKB=F6RLI6	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000050474.1\|UniProtKB=A0A6I8NL73	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024623.1\|UniProtKB=F1NLC8	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000010012.4\|UniProtKB=G1KJL8	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000007741.4\|UniProtKB=G1KHA3	Anolis carolinensis	LDO
XENLA\|Gene=nrdc.L\|UniProtKB=A0A1L8GMF3	Xenopus laevis	O
XENLA\|Gene=nrdc.S\|UniProtKB=A0A1L8GFX3	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-970569\|UniProtKB=F7AJT5	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000014051.2\|UniProtKB=H2MG88	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050208-422\|UniProtKB=Q1L985	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-070912-417\|UniProtKB=B0S6B9	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000009851.1\|UniProtKB=W5MUK5	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118431674\|UniProtKB=A0A9J7MCP9	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC583323\|UniProtKB=A0A7M7T3Y2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115918983\|UniProtKB=A0A7M7PJR7	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0037037\|UniProtKB=Q9VP94	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0030344\|UniProtKB=Q9VYT3	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP029563\|UniProtKB=A0A453Z049	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC003912\|UniProtKB=D6WHA9	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_57907\|UniProtKB=E9H390	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW011140\|UniProtKB=B7Q5D6	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g194611\|UniProtKB=A7SXQ6	Nematostella vectensis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_34450\|UniProtKB=A9VBU7	Monosiga brevicollis	LDO
PARTE\|EnsemblGenome=GSPATT00021051001\|UniProtKB=A0DWJ1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00006701001\|UniProtKB=A0C9C8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016702001\|UniProtKB=A0DFS2	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_2118\|UniProtKB=B8BTF3	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_263431\|UniProtKB=B8C782	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GFR9_PHYRM\|UniProtKB=H3GFR9	Phytophthora ramorum	LDO
AMBTC\|EnsemblGenome=AMTR_s00077p00061270\|UniProtKB=W1P2P4	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_196G00410\|UniProtKB=A0A0K9PP00	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma09_g04730\|UniProtKB=A0A804KG04	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_034044mg\|UniProtKB=K4A590	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G380600\|UniProtKB=A0A1B6QNE7	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb395090\|UniProtKB=K7VZS5	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os03g0336300\|UniProtKB=Q10LS9	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g63160v3\|UniProtKB=I1H5R2	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0378550\|UniProtKB=F2DL66	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS4A02G135700\|UniProtKB=A0A3B6HV11	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4B02G169500\|UniProtKB=A0A3B6IPD4	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4D02G171500\|UniProtKB=A0A3B6JK42	Triticum aestivum	LDO
NELNU\|Gene=LOC104594500\|UniProtKB=A0A1U7ZH31	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110797389\|UniProtKB=A0A9R0IYV0	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr08g0346621\|UniProtKB=A0A251U721	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C900462080\|UniProtKB=A0A9R1UEC3	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a000651mg\|UniProtKB=A0A022RZS0	Erythranthe guttata	LDO
SOLLC\|EnsemblGenome=Solyc02g043860.3\|UniProtKB=A0A3Q7EXV6	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107776904\|UniProtKB=A0A1S3YJC1	Nicotiana tabacum	O
TOBAC\|Gene=LOC107765001\|UniProtKB=A0A1S3XH84	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi06g00791\|UniProtKB=D7SJJ6	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_B04025\|UniProtKB=A0A059DAS1	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00055401001\|UniProtKB=A0A078H8M6	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A02P38070.1\|UniProtKB=A0A078H8T6	Brassica napus	O
BRACM\|EnsemblGenome=Bra020643\|UniProtKB=M4DVU9	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00031719001\|UniProtKB=A0A078FD18	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00032056001\|UniProtKB=A0A078FB24	Brassica napus	LDO
BRANA\|Gene_ORFName=GSBRNA2T00014792001\|UniProtKB=A0A078IXJ8	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra030665\|UniProtKB=M4EPE5	Brassica campestris	O
BRACM\|EnsemblGenome=Bra015536\|UniProtKB=M4DGB3	Brassica campestris	LDO
ARATH\|TAIR=locus=2033082\|UniProtKB=F4HNU6	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107927136\|UniProtKB=A0A1U8LGF1	Gossypium hirsutum	O
GOSHI\|Gene=LOC107963825\|UniProtKB=A0A1U8PXD4	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_042283\|UniProtKB=A0A061GYV7	Theobroma cacao	LDO
POPTR\|EnsemblGenome=POPTR_013G154600v3\|UniProtKB=A0A2K1Y636	Populus trichocarpa	LDO
RICCO\|Gene_ORFName=RCOM_0815980\|UniProtKB=B9RX17	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_11G160300\|UniProtKB=A0A0R0HRF3	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_18G053700\|UniProtKB=I1MZR2	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_5g095180\|UniProtKB=G7K4K4	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_3g466820\|UniProtKB=A0A072UY22	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr14_07640\|UniProtKB=A0A2I4FA53	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_6G205830\|UniProtKB=A0A0A0KEE3	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_6G041900\|UniProtKB=M5WR62	Prunus persica	O
PRUPE\|EnsemblGenome=PRUPE_6G041800\|UniProtKB=M5WJA8	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_154839\|UniProtKB=D8SF18	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_157708\|UniProtKB=D8SRL9	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c1_4220\|UniProtKB=A0A2K1L6U5	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c5_6610\|UniProtKB=A0A2K1KIQ4	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0029s0118\|UniProtKB=A0A2R6X928	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_002240200\|UniProtKB=A0A1Y1I718	Klebsormidium nitens	LDO