PANTHER Gene Information

Gene Symbol(s):

SYT1

Organism:

Felis catus

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Gene Name:

Synaptotagmin

Gene ID:

ENSFCAG00000024865.4

Protein ID:

A0A337STW9

Persistent Id:

PTN002224564

Alternate Ids:

XM_011284134(refSeq)	ENSFCAP00000049870(Ensembl_PRO)
ENSFCAG00000024865(Ensembl)	755749917(GI)
A0A337STW9(Synonym)	ENSFCAT00000059664(Ensembl_TRS)
A0A337STW9_FELCA(UniProtKB-ID)	AANG04003655(EMBL)
654422(GeneID)
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PANTHER Classification

PANTHER Family:	SYNAPTOTAGMIN (PTHR10024)
PANTHER Subfamily:	SYNAPTOTAGMIN-1 (PTHR10024:SF239)
PANTHER GO-slim Molecular Function:	SNARE binding calcium ion binding phosphatidylserine binding clathrin binding
PANTHER GO-slim Biological Process:	synaptic vesicle exocytosis synaptic vesicle endocytosis calcium-ion regulated exocytosis
PANTHER GO-slim Cellular Component:	axon plasma membrane synaptic vesicle membrane secretory granule
PANTHER protein class:	membrane trafficking regulatory protein

Pathway Categories:

Synaptic vesicle trafficking

Synaptotagmin

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	low-density lipoprotein particle receptor binding, metal ion binding, calcium ion binding, syntaxin-1 binding, calcium ion sensor activity, calcium-dependent protein binding, lipid binding, SNARE binding, calcium-dependent phospholipid binding
GO BP Complete:	regulation of dopamine secretion, positive regulation of dendrite extension, positive regulation of calcium ion-dependent exocytosis of neurotransmitter, positive regulation of synaptic transmission, spontaneous neurotransmitter secretion, neurotransmitter secretion, calcium ion-regulated exocytosis of neurotransmitter, vesicle-mediated transport, vesicle organization, calcium-dependent activation of synaptic vesicle fusion, regulation of synaptic vesicle exocytosis, fast, calcium ion-dependent exocytosis of neurotransmitter, synaptic vesicle exocytosis, regulation of calcium ion-dependent exocytosis, regulation of synaptic transmission, glutamatergic, synchronous neurotransmitter secretion
GO CC Complete:	presynaptic membrane, synaptic vesicle, secretory granule, chromaffin granule membrane, Golgi apparatus, synapse, neuron projection, plasma membrane, exocytic vesicle, cytoplasm, membrane, cytoplasmic vesicle, synaptic vesicle membrane, dense core granule, glutamatergic synapse, axon

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11509\|UniProtKB=P21579	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000024064.5\|UniProtKB=H2R3R2	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000024224.2\|UniProtKB=G3S3Z1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000005530.4\|UniProtKB=F7GFB1	Macaca mulatta	LDO
MOUSE\|MGI=MGI=99667\|UniProtKB=P46096	Mus musculus	LDO
RAT\|RGD=3803\|UniProtKB=P21707	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000034693\|UniProtKB=P48018	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000000948.5\|UniProtKB=F1RYK1	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000012832.4\|UniProtKB=F6R134	Equus caballus	LDO
CANLF\|Ensembl=ENSCAFG00845007651.1\|UniProtKB=A0A8I3N2E5	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000020467.5\|UniProtKB=F7FJ84	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000007531.4\|UniProtKB=A0A6I8PE80	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010012026\|UniProtKB=P47191	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000013826.3\|UniProtKB=G1KPD2	Anolis carolinensis	LDO
XENLA\|Gene=LOC108713136\|UniProtKB=A0A1L8GUB6	Xenopus laevis	O
XENLA\|Gene=LOC108711107\|UniProtKB=A0A1L8GYR8	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5752629\|UniProtKB=A0A803JC88	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000008768.2\|UniProtKB=H2LY02	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000016339.2\|UniProtKB=A0A3B3H997	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040718-165\|UniProtKB=Q5TZ27	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000016283.1\|UniProtKB=W5NHI2	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006816.3\|UniProtKB=F6TZR8	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_120531\|UniProtKB=C3Z4L9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118417681\|UniProtKB=A0A9J7LAS0	Branchiostoma floridae	LDO
BRAFL\|Gene=LOC118406658\|UniProtKB=A0A9J7KK38	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC752447\|UniProtKB=A0A7M7NZL4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC755798\|UniProtKB=A0A7M7G0T7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115917880\|UniProtKB=A0A7M7NYG5	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC115921646\|UniProtKB=A0A7M7NGD2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC373478\|UniProtKB=A0A7M7NYD5	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00004925\|UniProtKB=O16700	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00028699\|UniProtKB=A8X269	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00118488\|UniProtKB=A0A2A6C9X4	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00004922\|UniProtKB=K8FE10	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00035598\|UniProtKB=A8XLH0	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00090226\|UniProtKB=A0A2A6BQW9	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00008438\|UniProtKB=G5EDP5	Caenorhabditis elegans	O
PRIPA\|EnsemblGenome=WBGene00091526\|UniProtKB=A0A2A6CXX6	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00004923\|UniProtKB=Q965S5	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00028703\|UniProtKB=A8X273	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00118741\|UniProtKB=A0A2A6CGF4	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00004921\|UniProtKB=P34693	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00032329\|UniProtKB=A8XCL2	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00097802\|UniProtKB=A0A2A6BZB9	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0261089\|UniProtKB=C0HDP4	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP008650\|UniProtKB=A0A1S4GYU8	Anopheles gambiae	O
DROME\|FlyBase=FBgn0004242\|UniProtKB=P21521	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP007942\|UniProtKB=Q7PN22	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC007227\|UniProtKB=D2A0P6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_442623\|UniProtKB=E9FTC0	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW011463\|UniProtKB=B7Q6I0	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG170390\|UniProtKB=T1F2Z9	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG65797\|UniProtKB=T1FYC7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG163371\|UniProtKB=T1ETY8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG78642\|UniProtKB=T1G3E0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG82086\|UniProtKB=T1G4M6	helobdella robusta	LDO
HELRO\|EnsemblGenome=HelroG85838\|UniProtKB=T1G633	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g247877\|UniProtKB=A7SX18	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g85661\|UniProtKB=A7RKX9	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g136167\|UniProtKB=A7SX19	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g115870\|UniProtKB=A7SEZ4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g136571\|UniProtKB=A7SXC9	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g130783\|UniProtKB=A7ST77	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g136185\|UniProtKB=A7SX17	Nematostella vectensis	LDO
TRIAD\|Gene_ORFName=TRIADDRAFT_61791\|UniProtKB=B3SBZ4	Trichoplax adhaerens	LDO