PANTHER Gene Information

Gene Symbol(s):

GOT1

Organism:

Felis catus

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Gene Name:

Aspartate aminotransferase

Gene ID:

ENSFCAG00000028066.4

Protein ID:

M3X6W4

Persistent Id:

PTN001725637

Alternate Ids:

755776713(GI)	101085155(GeneID)
M3X6W4(Synonym)	ENSFCAG00000028066(Ensembl)
ENSFCAT00000031561(Ensembl_TRS)	ENSFCAP00000022366(Ensembl_PRO)
XP_011285783(refSeq)	M3X6W4_FELCA(UniProtKB-ID)
AANG04000273(EMBL)
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PANTHER Classification

PANTHER Family:	ASPARTATE AMINOTRANSFERASE (PTHR11879)
PANTHER Subfamily:	ASPARTATE AMINOTRANSFERASE, CYTOPLASMIC (PTHR11879:SF3)
PANTHER GO-slim Molecular Function:	transaminase activity
PANTHER GO-slim Biological Process:	aspartate metabolic process aspartate family amino acid biosynthetic process
PANTHER GO-slim Cellular Component:	cytosol
PANTHER protein class:	transaminase

Pathway Categories:

Asparagine and aspartate biosynthesis

Aspartate aminotransferase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	pyridoxal phosphate binding, transaminase activity, phosphatidylserine decarboxylase activity, L-aspartate:2-oxoglutarate aminotransferase activity, L-cysteine transaminase activity
GO BP Complete:	gluconeogenesis, fatty acid homeostasis, amino acid metabolic process, amino acid biosynthetic process, biosynthetic process, glycerol biosynthetic process, aspartate biosynthetic process, aspartate catabolic process, cellular response to insulin stimulus, oxaloacetate metabolic process, Notch signaling pathway, glutamate catabolic process to 2-oxoglutarate, glutamate catabolic process to aspartate, response to glucocorticoid
GO CC Complete:	cytoplasm, cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=4432\|UniProtKB=P17174	Homo sapiens	LDO
PANTR\|Gene=GOT1\|UniProtKB=A5A6K8	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000002829.5\|UniProtKB=H2Q2E4	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000002550.3\|UniProtKB=G3QJC1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000010356.4\|UniProtKB=H9EVG6	Macaca mulatta	LDO
MOUSE\|MGI=MGI=95791\|UniProtKB=P05201	Mus musculus	LDO
RAT\|RGD=2721\|UniProtKB=P13221	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000011960\|UniProtKB=P33097	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000010537\|UniProtKB=P00503	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000000095.4\|UniProtKB=A0A9L0TGC2	Equus caballus	O
HORSE\|Gene=GOT1\|UniProtKB=P08906	Equus caballus	LDO
CANLF\|Ensembl=ENSCAFG00845030772.1\|UniProtKB=A0A8I3QCW7	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000003558.4\|UniProtKB=F7GBD3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000006868.4\|UniProtKB=F7CRD7	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010018323\|UniProtKB=P00504	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000003583.4\|UniProtKB=G1KC46	Anolis carolinensis	LDO
XENLA\|Gene=got1.S\|UniProtKB=Q7ZTK9	Xenopus laevis	LDO
XENLA\|Gene=LOC108697935\|UniProtKB=A0A8J0TH83	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-954930\|UniProtKB=Q6NX26	Xenopus tropicalis	LDO
DANRE\|ZFIN=ZDB-GENE-060929-556\|UniProtKB=B0UYT6	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000014957.1\|UniProtKB=W5NCQ7	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000007741.2\|UniProtKB=H2LUB7	Oryzias latipes	LDO
ORYLA\|Ensembl=ENSORLG00000000031.2\|UniProtKB=H2L2T9	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040426-2003\|UniProtKB=Q7ZUW8	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000009054.1\|UniProtKB=W5MRN1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000008364.3\|UniProtKB=F7AJP1	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118413807\|UniProtKB=A0A9J7KZQ0	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC589279\|UniProtKB=A0A7M7NXJ2	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00020146\|UniProtKB=Q22067	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00036251\|UniProtKB=A8XNT7	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00036252\|UniProtKB=A8XNT6	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00279811\|UniProtKB=A0A2A6CJU2	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00273223\|UniProtKB=A0A2A6C546	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0001124\|UniProtKB=A1ZAA5	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP004142\|UniProtKB=Q7QB79	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC014364\|UniProtKB=A0A139WGX0	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_308666\|UniProtKB=E9H8T5	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW014718\|UniProtKB=B7QLB0	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG158112\|UniProtKB=T1EMJ5	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g246662\|UniProtKB=A7SPW2	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG51058\|UniProtKB=B3SB31	Trichoplax adhaerens	LDO
YEAST\|SGD=S000004017\|UniProtKB=P23542	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFR211C\|UniProtKB=Q753W1	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000188482\|UniProtKB=A0A1D8PL85	Candida albicans	O
CANAL\|CGD=CAL0000174616\|UniProtKB=Q59N40	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F29337g\|UniProtKB=Q6BZZ9	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_08709\|UniProtKB=Q5ASM1	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G04160\|UniProtKB=Q4WK05	Neosartorya fumigata	O
ASPFU\|EnsemblGenome=AFUA_6G02490\|UniProtKB=Q4WCU8	Neosartorya fumigata	O
PHANO\|Gene_ORFName=SNOG_08796\|UniProtKB=Q0UHG8	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_06048\|UniProtKB=Q5B082	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_2G09650\|UniProtKB=Q4X1K5	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU07941\|UniProtKB=Q7S9X7	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_14097\|UniProtKB=A7F916	Sclerotinia sclerotiorum	LDO
SCHPO\|PomBase=SPAC10F6.13c\|UniProtKB=O42652	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_03306\|UniProtKB=B6K3W4	Schizosaccharomyces japonicus	LDO
USTMA\|EnsemblGenome=UMAG_04562\|UniProtKB=A0A0D1CL29	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_10702\|UniProtKB=E3KJR8	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_19087\|UniProtKB=F4NY01	Batrachochytrium dendrobatidis	LDO
LEIMA\|EnsemblGenome=LMJF_35_0820\|UniProtKB=Q4FX34	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb10.70.3710\|UniProtKB=Q38BN3	Trypanosoma brucei	LDO
CHLTR\|EnsemblGenome=CT_637\|UniProtKB=O84642	Chlamydia trachomatis	O
RHOBA\|EnsemblGenome=RB12864\|UniProtKB=Q7UHY8	Rhodopirellula baltica	O
FUSNN\|EnsemblGenome=FN0334\|UniProtKB=Q8RGG4	Fusobacterium nucleatum	O
NEIMB\|EnsemblGenome=NMB1678\|UniProtKB=Q9JYA1	Neisseria meningitidis serogroup b	O
XANCP\|EnsemblGenome=XCC0097\|UniProtKB=Q8PE84	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA3139\|UniProtKB=P72173	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM4248\|UniProtKB=P74861	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO0322\|UniProtKB=A0A2S9PJM4	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE78056\|UniProtKB=P04693	Escherichia coli	O
NEIMB\|EnsemblGenome=NMB0540\|UniProtKB=Q9K0P5	Neisseria meningitidis serogroup b	O
HAEIN\|EnsemblGenome=HI_1617\|UniProtKB=P44425	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_2406\|UniProtKB=Q8EEH6	Shewanella oneidensis	O
SHEON\|Gene_OrderedLocusName=SO_2350\|UniProtKB=Q8EEM8	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_A0513\|UniProtKB=Q9KM75	Vibrio cholerae	O
VIBCH\|EnsemblGenome=VC_1293\|UniProtKB=Q9KSG3	Vibrio cholerae	O
PSEAE\|EnsemblGenome=PA0870\|UniProtKB=P43336	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM0998\|UniProtKB=P58661	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO1410\|UniProtKB=A0A3N4B4N9	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA35674\|UniProtKB=P00509	Escherichia coli	O