PANTHER Gene Information

Gene Symbol(s):

FGF21

Organism:

Gorilla gorilla gorilla

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Gene Name:

Fibroblast growth factor

Gene ID:

ENSGGOG00000001246.3

Protein ID:

G3QFY8

Persistent Id:

PTN002608287

Alternate Ids:

ENSGGOT00000001253(Ensembl_TRS)	XM_004061102(refSeq)
ENSGGOG00000001246(Ensembl)	ENSGGOP00000001229(Ensembl_PRO)
CABD030114232(EMBL)	101149990(GeneID)
G3QFY8(Synonym)	426389482(GI)
G3QFY8_GORGO(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	FIBROBLAST GROWTH FACTOR (PTHR11486)
PANTHER Subfamily:	FIBROBLAST GROWTH FACTOR 21 (PTHR11486:SF81)
PANTHER GO-slim Molecular Function:	growth factor activity fibroblast growth factor receptor binding
PANTHER GO-slim Biological Process:	regulation of cell migration fibroblast growth factor receptor signaling pathway positive regulation of protein phosphorylation cell differentiation positive regulation of MAPK cascade positive regulation of gene expression positive regulation of cell population proliferation animal organ morphogenesis
PANTHER GO-slim Cellular Component:	extracellular space cytoplasm
PANTHER protein class:	growth factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	growth factor activity, fibroblast growth factor receptor binding
GO BP Complete:	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway, positive regulation of cell population proliferation, positive regulation of ERK1 and ERK2 cascade, fibroblast growth factor receptor signaling pathway, positive regulation of D-glucose import, neurogenesis, positive regulation of MAPK cascade, regulation of cell migration, positive regulation of cold-induced thermogenesis
GO CC Complete:	extracellular space, cytoplasm, extracellular region

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3678\|UniProtKB=Q9NSA1	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000011257.5\|UniProtKB=A0A2J8K2A2	Pan troglodytes	LDO
MACMU\|Ensembl=ENSMMUG00000028737.3\|UniProtKB=F6ZFI2	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1861377\|UniProtKB=Q9JJN1	Mus musculus	LDO
RAT\|RGD=620175\|UniProtKB=F7FG05	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000011624.2\|UniProtKB=E1BDA6	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000003140.5\|UniProtKB=C6JWG4	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000010695.3\|UniProtKB=F6R1Q0	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000007365.5\|UniProtKB=M3W7L7	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845000788.1\|UniProtKB=E2RRP8	Canis lupus familiaris	LDO
ANOCA\|Ensembl=ENSACAG00000017175.4\|UniProtKB=R4GC04	Anolis carolinensis	LDO
XENLA\|Gene=LOC108696768\|UniProtKB=A0A1L8FNK1	Xenopus laevis	O
XENTR\|Gene=LOC105947943\|UniProtKB=A0A8J0SJM1	Xenopus tropicalis	O
XENLA\|Gene=fgf19.S\|UniProtKB=A0A1L8GDL8	Xenopus laevis	O
XENLA\|Gene=fgf19.L\|UniProtKB=A0A1L8GIT6	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-486499\|UniProtKB=B7U4G3	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000027052.1\|UniProtKB=A0A3B3HCR8	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-060623-2\|UniProtKB=Q1ESX2	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000000289.2\|UniProtKB=H2L3M7	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030729-32\|UniProtKB=A0A0R4IN60	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000005100.1\|UniProtKB=W5MCN1	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000005062.3\|UniProtKB=F7A4U1	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000000625.3\|UniProtKB=F6RRN2	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000004434.3\|UniProtKB=F6Y3G3	Ciona intestinalis	O
BRAFL\|Gene=LOC118415060\|UniProtKB=A0A9J7MP55	Branchiostoma floridae	O
BRAFL\|Gene=LOC118414951\|UniProtKB=A0A9J7L3F3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118415257\|UniProtKB=A0A9J7MQU2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409786\|UniProtKB=A0A9J7KN24	Branchiostoma floridae	O
BRAFL\|Gene=LOC118419857\|UniProtKB=A0A9J7LH78	Branchiostoma floridae	O
STRPU\|EnsemblGenome=GeneID_582058\|UniProtKB=G3CLF6	Strongylocentrotus purpuratus	O
DROME\|FlyBase=FBgn0014135\|UniProtKB=Q9VDT9	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP004181\|UniProtKB=A0NDD8	Anopheles gambiae	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_108237\|UniProtKB=E9GZJ7	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW015993\|UniProtKB=B7P1T5	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g212165\|UniProtKB=A7SH09	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g244903\|UniProtKB=A7SFH7	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g196402\|UniProtKB=A7RFG7	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g247007\|UniProtKB=A7SRV4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g217516\|UniProtKB=A7SU37	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g211797\|UniProtKB=A7SG69	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g212596\|UniProtKB=A7SI24	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g16985\|UniProtKB=A7SI25	Nematostella vectensis	O