PANTHER Gene Information

Gene Symbol(s):

NDFIP1

Organism:

Gorilla gorilla gorilla

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Gene Name:

Nedd4 family interacting protein 1

Gene ID:

ENSGGOG00000004879.3

Protein ID:

G3QQB6

Persistent Id:

PTN002667650

Alternate Ids:

101149611(GeneID)	ENSGGOP00000004780(Ensembl_PRO)
G3QQB6(Synonym)	ENSGGOT00000004903(Ensembl_TRS)
ENSGGOG00000004879(Ensembl)	CABD030041433(EMBL)
XP_004042777(refSeq)	426350431(GI)
G3QQB6_GORGO(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	NEDD4 FAMILY INTERACTING PROTEIN 1/2 (PTHR13396)
PANTHER Subfamily:	NEDD4 FAMILY-INTERACTING PROTEIN 1 (PTHR13396:SF3)
PANTHER GO-slim Molecular Function:	protein binding
PANTHER GO-slim Biological Process:	positive regulation of protein modification process ubiquitin-dependent protein catabolic process metal ion transport
PANTHER GO-slim Cellular Component:	Golgi apparatus perinuclear region of cytoplasm endoplasmic reticulum
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	WW domain binding
GO BP Complete:	regulation of lymphocyte differentiation, protein catabolic process, negative regulation of inflammatory response, positive regulation of protein catabolic process, vacuolar transport, regulation of myeloid leukocyte differentiation, ubiquitin-dependent protein catabolic process, intracellular iron ion homeostasis, negative regulation of protein transport, negative regulation of gene expression, negative regulation of interleukin-4 production, regulation of isotype switching to IgG isotypes, CD4-positive, alpha-beta T cell proliferation, positive regulation of protein ubiquitination, negative regulation of type 2 immune response, metal ion transport, negative regulation of isotype switching to IgE isotypes, negative regulation of CD4-positive, alpha-beta T cell proliferation
GO CC Complete:	perinuclear region of cytoplasm, cytoplasm, cell cortex, membrane, endomembrane system, Golgi membrane, endoplasmic reticulum, Golgi apparatus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=17592\|UniProtKB=Q9BT67	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000017358.6\|UniProtKB=H2QRP2	Pan troglodytes	LDO
MACMU\|Ensembl=ENSMMUG00000016787.4\|UniProtKB=F7D4X8	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1929601\|UniProtKB=Q8R0W6	Mus musculus	LDO
RAT\|RGD=1310053\|UniProtKB=Q5U2S1	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000047747.2\|UniProtKB=A0A3Q1MAX3	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000025295.4\|UniProtKB=A0A287B0W0	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000021907.4\|UniProtKB=A0A9L0SMK6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000009405.6\|UniProtKB=M3WBD5	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845017691.1\|UniProtKB=A0A8I3P1A5	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000010383.4\|UniProtKB=F7AV91	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000044026.1\|UniProtKB=A0A6I8NFZ8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010013353.1\|UniProtKB=A0A8V0YJD5	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000013413.4\|UniProtKB=G1KNQ5	Anolis carolinensis	LDO
XENLA\|Gene=ndfip1\|UniProtKB=Q6GLN5	Xenopus laevis	O
XENLA\|Gene=ndfip1.L\|UniProtKB=A0A8J0URI6	Xenopus laevis	O
XENLA\|Gene=ndfip1.S\|UniProtKB=A1A647	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-961957\|UniProtKB=Q4V786	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000006004.2\|UniProtKB=H2LNC4	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000001479.2\|UniProtKB=A0A3B3I4H2	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-2767\|UniProtKB=F1QQT7	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-040718-207\|UniProtKB=Q6DGP4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000010551.1\|UniProtKB=W5MX23	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000016491.2\|UniProtKB=F6YMW5	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118418905\|UniProtKB=A0A9J7MW10	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC577415\|UniProtKB=A0A7M7HP41	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0052177\|UniProtKB=Q9VVJ5	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP005801\|UniProtKB=A0NEI4	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC008147\|UniProtKB=D2A028	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_309287\|UniProtKB=E9HBX4	Daphnia pulex	LDO
TRIAD\|EnsemblGenome=TriadG56783\|UniProtKB=B3RWK6	Trichoplax adhaerens	LDO
YEAST\|SGD=S000000494\|UniProtKB=P38356	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AGL063C\|UniProtKB=Q750M0	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000194432\|UniProtKB=A0A1D8PJV5	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F26301g\|UniProtKB=Q6C0B1	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_05668\|UniProtKB=C8VFS5	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_4G13740\|UniProtKB=Q4WQR5	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU05077\|UniProtKB=Q7RWK7	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_11836\|UniProtKB=A7F3J0	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_15721\|UniProtKB=Q0TXG1	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC328.07c\|UniProtKB=Q9P3T9	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_01527\|UniProtKB=B6JY68	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNM01680\|UniProtKB=Q5K7Q0	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_03045\|UniProtKB=A0A0D1DZR8	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_05429\|UniProtKB=E3K498	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_89747\|UniProtKB=F4P5W8	Batrachochytrium dendrobatidis	LDO