PANTHER Gene Information

Gene Symbol(s):

SIK2

Organism:

Gorilla gorilla gorilla

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Gene Name:

non-specific serine_threonine protein kinase

Gene ID:

ENSGGOG00000010247.3

Protein ID:

G3RWJ5

Persistent Id:

PTN002804611

Alternate Ids:

XP_004052156(refSeq)	426370407(GI)
ENSGGOP00000020178(Ensembl_PRO)	G3RWJ5_GORGO(UniProtKB-ID)
CABD030081561(EMBL)	101133594(GeneID)
ENSGGOT00000024475(Ensembl_TRS)	G3RWJ5(Synonym)
ENSGGOG00000010247(Ensembl)
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PANTHER Classification

PANTHER Family:	MAP/MICROTUBULE AFFINITY-REGULATING KINASE (PTHR24346)
PANTHER Subfamily:	NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE (PTHR24346:SF38)
PANTHER GO-slim Molecular Function:	protein serine/threonine kinase activity
PANTHER GO-slim Biological Process:	microtubule cytoskeleton organization intracellular signal transduction
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	non-receptor serine/threonine protein kinase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	magnesium ion binding, ribosomal protein S6 kinase activity, DNA-dependent protein kinase activity, ATP binding, histone H2AT120 kinase activity, AMP-activated protein kinase activity, histone H3S57 kinase activity, histone H4S1 kinase activity, histone H3S28 kinase activity, histone H3T45 kinase activity, histone H2AXS139 kinase activity, protein serine kinase activity, histone H3S10 kinase activity, histone H2BS14 kinase activity, histone H2AS1 kinase activity, eukaryotic translation initiation factor 2alpha kinase activity, protein serine/threonine kinase activity, 3-phosphoinositide-dependent protein kinase activity, tau-protein kinase activity, histone H2AS121 kinase activity, histone H3T3 kinase activity, histone H2BS36 kinase activity, Rho-dependent protein serine/threonine kinase activity, histone H3T11 kinase activity, histone H3T6 kinase activity
GO BP Complete:	chromatin remodeling, microtubule cytoskeleton organization, intracellular signal transduction
GO CC Complete:	endoplasmic reticulum membrane, cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
CHICK\|Ensembl=ENSGALG00010024415.1\|UniProtKB=A0A8V0ZSB4	Gallus gallus	LDO
XENLA\|Gene=sik2.S\|UniProtKB=A0A1L8FFT4	Xenopus laevis	LDO
XENLA\|Gene=sik2.L\|UniProtKB=A0A1L8FLQ7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-950070\|UniProtKB=A0A6I8SYG1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000007465.2\|UniProtKB=A0A3B3HIM1	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000001288.1\|UniProtKB=W5LZB8	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118414265\|UniProtKB=A0A9J7L0Y2	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC589243\|UniProtKB=A0A7M7HP76	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC578417\|UniProtKB=A0A7M7GF11	Strongylocentrotus purpuratus	LDO
TRICA\|EnsemblGenome=TC007481\|UniProtKB=D1ZZB2	Tribolium castaneum	LDO
HELRO\|EnsemblGenome=HelroG65239\|UniProtKB=T1FY49	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67067\|UniProtKB=T1FYV8	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g139527\|UniProtKB=A7SZV3	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG27001\|UniProtKB=B3S0C9	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_34468\|UniProtKB=A9VBY4	Monosiga brevicollis	O
CANAL\|CGD=CAL0000177153\|UniProtKB=A0A1D8PRN8	Candida albicans	O
ASPFU\|EnsemblGenome=AFUA_1G11080\|UniProtKB=Q4WSZ7	Neosartorya fumigata	O
SCHJY\|EnsemblGenome=SJAG_02838\|UniProtKB=B6K1B3	Schizosaccharomyces japonicus	O
ASPFU\|EnsemblGenome=AFUA_1G11930\|UniProtKB=E9RDZ3	Neosartorya fumigata	O
SCHJY\|EnsemblGenome=SJAG_04469\|UniProtKB=B6K6W9	Schizosaccharomyces japonicus	O
SCHJY\|EnsemblGenome=SJAG_03602\|UniProtKB=B6K4P0	Schizosaccharomyces japonicus	O
BATDJ\|Gene_ORFName=BATDEDRAFT_10042\|UniProtKB=F4NZ62	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_073490\|UniProtKB=C4LXL3	Entamoeba histolytica	O
ENTH1\|Gene_ORFName=EHI_025300\|UniProtKB=A0A8U0WP54	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0280133\|UniProtKB=Q54VU4	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_151676\|UniProtKB=F0ZJH1	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0292304\|UniProtKB=Q54DF2	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_51418\|UniProtKB=F1A3P4	Dictyostelium purpureum	O
GIAIC\|EnsemblGenome=GL50803_9487\|UniProtKB=A8B530	Giardia intestinalis	O
PLAF7\|EnsemblGenome=PF3D7_1441300\|UniProtKB=Q8IL57	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00031618001\|UniProtKB=A0BS70	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00002297001\|UniProtKB=A0DGK1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00020040001\|UniProtKB=A0DTJ2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00018964001\|UniProtKB=A0DP01	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00030300001\|UniProtKB=A0BM97	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00004376001\|UniProtKB=A0BCL5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00018952001\|UniProtKB=A0DNY9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026401001\|UniProtKB=A0EFI7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00024498001\|UniProtKB=A0E900	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00024481001\|UniProtKB=A0E8Y3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00017966001\|UniProtKB=A0DKR9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028068001\|UniProtKB=A0BER8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00022278001\|UniProtKB=A0E1E2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00009964001\|UniProtKB=A0CSC5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00025088001\|UniProtKB=A0EAN7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00029968001\|UniProtKB=A0BLB9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00014139001\|UniProtKB=A0D805	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00019068001\|UniProtKB=A0DPB9	Paramecium tetraurelia	O
PHYRM\|Gene=H3H0P0_PHYRM\|UniProtKB=H3H0P0	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_07g329850v5\|UniProtKB=A0A2K3DJR9	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_09g403850v5\|UniProtKB=A0A2K3DCM7	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g568050v5\|UniProtKB=A0A2K3CZG1	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_16g685389v5\|UniProtKB=A0A2K3CW32	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_02g076000v5\|UniProtKB=A0A2K3E058	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_01g036000v5\|UniProtKB=A0A2K3E716	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_06g251050v5\|UniProtKB=A0A2K3DLY4	Chlamydomonas reinhardtii	O
HELAN\|Gene_ORFName=HanXRQr2_Chr05g0231561\|UniProtKB=A0A9K3J1W2	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C500236580\|UniProtKB=A0A9R1XB86	Lactuca sativa	O
KLENI\|Gene_ORFName=KFL_000330150\|UniProtKB=A0A1Y1HQV7	Klebsormidium nitens	O
LACSA\|Gene_ORFName=LSAT_V11C400212270\|UniProtKB=A0A9R1XHY6	Lactuca sativa	O
KLENI\|Gene_ORFName=KFL_000980330\|UniProtKB=A0A0U9HJG2	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_007820030\|UniProtKB=A0A1Y1IQA2	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_001250250\|UniProtKB=A0A1Y1I3Z9	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000970360\|UniProtKB=A0A0U9HJE6	Klebsormidium nitens	O
MUSAM\|EnsemblGenome=Ma01_g02460\|UniProtKB=A0A804HPI0	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma00_g00400\|UniProtKB=A0A804HLY2	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma10_g08280\|UniProtKB=A0A804KTZ1	Musa acuminata subsp. malaccensis	O
MAIZE\|EnsemblGenome=Zm00001eb013270\|UniProtKB=Q6RXY1	Zea mays	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0320770\|UniProtKB=A0A8I7BB45	Hordeum vulgare subsp. vulgare	O
SETIT\|EnsemblGenome=SETIT_019716mg\|UniProtKB=K3YZK6	Setaria italica	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0060110\|UniProtKB=A0A8I6X3U9	Hordeum vulgare subsp. vulgare	O
MAIZE\|EnsemblGenome=Zm00001eb293240\|UniProtKB=A0A804Q4X7	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb353700\|UniProtKB=A0A804QSJ7	Zea mays	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0286490\|UniProtKB=A0A8I6XFN7	Hordeum vulgare subsp. vulgare	O
SPIOL\|Gene=LOC110800356\|UniProtKB=A0A9R0J5M8	Spinacia oleracea	O
HELAN\|Gene_ORFName=HanXRQr2_Chr07g0308661\|UniProtKB=A0A9K3ING8	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C900467660\|UniProtKB=A0A9R1UGU9	Lactuca sativa	O
PHYPA\|EnsemblGenome=Pp3c3_5570\|UniProtKB=A0A7I4DGQ5	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0038s0082\|UniProtKB=A0A2R6X3U9	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0160s0010\|UniProtKB=A0A2R6W3Y3	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_008220030\|UniProtKB=A0A1Y1INE1	Klebsormidium nitens	O
STRCO\|Gene_OrderedLocusName=SCO4820\|UniProtKB=Q9K3K0	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO4817\|UniProtKB=Q9K3K3	Streptomyces coelicolor	O
DEIRA\|EnsemblGenome=DR_1213\|UniProtKB=Q9RV17	Deinococcus radiodurans	O
RHOBA\|EnsemblGenome=RB12694\|UniProtKB=Q7UI82	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_576\|UniProtKB=O66844	Aquifex aeolicus	O