PANTHER Gene Information

Gene Symbol(s):

ANG

Organism:

Gorilla gorilla gorilla

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Gene Name:

Angiogenin

Gene ID:

ANG

Protein ID:

Q71MJ0

Persistent Id:

PTN002605980

Alternate Ids:

3.1.27.-(EC)	ANGI_GORGO(UniProtKB-ID)
RNase 5(Synonym)	ANG(Symbol)
AF441662(EMBL)	18150520(GI)
AAL61644(EMBL-CDS)
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PANTHER Classification

PANTHER Family:	RIBONUCLEASE (PTHR11437)
PANTHER Subfamily:	ANGIOGENIN (PTHR11437:SF60)
PANTHER GO-slim Molecular Function:	RNA nuclease activity
PANTHER GO-slim Biological Process:	antimicrobial humoral immune response mediated by antimicrobial peptide angiogenesis antibacterial humoral response defense response to Gram-positive bacterium innate immune response
PANTHER GO-slim Cellular Component:	extracellular space
PANTHER protein class:	endoribonuclease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	nucleic acid binding, DNA binding, protein homodimerization activity, actin binding, copper ion binding, endonuclease activity, RNA nuclease activity, heparin binding, signaling receptor binding
GO BP Complete:	actin filament polymerization, rRNA transcription, antimicrobial humoral immune response mediated by antimicrobial peptide, response to hypoxia, angiogenesis, negative regulation of apoptotic process, innate immune response, signaling, negative regulation of smooth muscle cell proliferation, cell differentiation, hematopoietic stem cell proliferation, antibacterial humoral response, positive regulation of endothelial cell proliferation, positive regulation of protein secretion, negative regulation of translation, defense response to Gram-positive bacterium
GO CC Complete:	nucleus, basement membrane, extracellular space, cytoplasmic stress granule, cytoplasm, angiogenin-PRI complex, extracellular region, nucleolus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=483\|UniProtKB=P03950	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000043768\|UniProtKB=Q8WME8	Pan troglodytes	LDO
MACMU\|Ensembl=ENSMMUG00000057652.1\|UniProtKB=A0A5F7ZAL9	Macaca mulatta	O
MACMU\|Gene=ANG\|UniProtKB=Q8WN63	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1201793\|UniProtKB=P97802	Mus musculus	O
MOUSE\|MGI=MGI=3528599\|UniProtKB=Q5GAN1	Mus musculus	O
MOUSE\|MGI=MGI=104984\|UniProtKB=Q64438	Mus musculus	O
MOUSE\|MGI=MGI=2656551\|UniProtKB=Q3TMQ6	Mus musculus	O
MOUSE\|MGI=MGI=3528602\|UniProtKB=Q5GAN0	Mus musculus	O
MOUSE\|MGI=MGI=88022\|UniProtKB=P21570	Mus musculus	LDO
RAT\|RGD=1359373\|UniProtKB=Q5GAM5	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000032873.4\|UniProtKB=F1MSQ0	Bos taurus	O
BOVIN\|Gene=ANG1\|UniProtKB=P10152	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000059608.1\|UniProtKB=Q1HDU1	Sus scrofa	LDO
PIG\|Gene=ANG\|UniProtKB=P31346	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000050635\|UniProtKB=Q5VI84	Equus caballus	LDO
MONDO\|Ensembl=ENSMODG00000006972.3\|UniProtKB=F6QUQ6	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010008443\|UniProtKB=P30374	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010011433\|UniProtKB=P27043	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010002667.1\|UniProtKB=A0A8V0X6Y3	Gallus gallus	O
CHICK\|Gene=RNL2_CHICK\|UniProtKB=P81476	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000007894.3\|UniProtKB=H9GD65	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000036212.1\|UniProtKB=A0A803T5A2	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000039056.1\|UniProtKB=A0A803TLP8	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000043896.1\|UniProtKB=H9GAD6	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000039552.1\|UniProtKB=A0A803SKJ8	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000038211.1\|UniProtKB=H9GAD8	Anolis carolinensis	O
ORYLA\|Ensembl=ENSORLG00000006418.2\|UniProtKB=H2LPS5	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000022214.1\|UniProtKB=A0A3B3I9G7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000029417.1\|UniProtKB=A0A3B3HT95	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000029156.1\|UniProtKB=A0A3B3H7B7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000029743.1\|UniProtKB=A0A3B3I5P0	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000022465.1\|UniProtKB=A0A3B3HMY3	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000025191.1\|UniProtKB=A0A3B3IDR8	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000030644.1\|UniProtKB=A0A3B3HSH1	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050809-5\|UniProtKB=A5HAK0	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-050208-420\|UniProtKB=A5HAK1	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000017307.1\|UniProtKB=W5NLA3	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000001488.1\|UniProtKB=W5M017	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000017306.1\|UniProtKB=W5NLA2	lepisosteus oculatus	O