PANTHER Gene Information

Gene Symbol(s):

20212066

Organism:

helobdella robusta

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Gene Name:

Metalloendopeptidase

Gene ID:

HelroG191792

Protein ID:

T1FTB9

Persistent Id:

PTN002901438

Alternate Ids:

XM_009019576(refSeq)	555700655(GI)
20212066(GeneID)	T1FTB9_HELRO(UniProtKB-ID)
AMQM01004401(EMBL)	T1FTB9(Synonym)
HelroG191792(Ensembl)	ESO03888(EMBL-CDS)
HelroP191792(Ensembl_PRO)	HelroT191792(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING (PTHR10127)
PANTHER Subfamily:	DORSAL-VENTRAL PATTERNING PROTEIN TOLLOID-RELATED (PTHR10127:SF861)
PANTHER GO-slim Molecular Function:	metalloendopeptidase activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	metalloprotease

Pathway Categories:

BMP/activin signaling pathway-drosophila

tolloid

TGF-beta signaling pathway

Transforming growth factor beta

DPP-SCW signaling pathway

tolloid

SCW signaling pathway

tolloid

DPP signaling pathway

tolloid

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	zinc ion binding, metal ion binding, calcium ion binding, metalloendopeptidase activity, metallopeptidase activity
GO BP Complete:	proteolysis, protein processing, dorsal/ventral pattern formation
GO CC Complete:	extracellular space

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=1067\|UniProtKB=P13497	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000020054.7\|UniProtKB=H2QVU7	Pan troglodytes	O
MACMU\|Ensembl=ENSMMUG00000013031.4\|UniProtKB=F7HAA9	Macaca mulatta	O
MOUSE\|MGI=MGI=88176\|UniProtKB=P98063	Mus musculus	O
RAT\|RGD=620739\|UniProtKB=F1M798	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000000917.6\|UniProtKB=E1BEV7	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000009620.5\|UniProtKB=F1RMB2	Sus scrofa	O
FELCA\|Ensembl=ENSFCAG00000012979.6\|UniProtKB=M3WHZ6	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845025214.1\|UniProtKB=A0A8I3PQL4	Canis lupus familiaris	O
ORNAN\|Ensembl=ENSOANG00000010775.3\|UniProtKB=A0A6I8P9E2	Ornithorhynchus anatinus	O
XENLA\|Gene=bmp1\|UniProtKB=P98070	Xenopus laevis	O
ORYLA\|Ensembl=ENSORLG00000008971.2\|UniProtKB=H2LYN2	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000011156.2\|UniProtKB=H2M6A6	Oryzias latipes	O
DANRE\|Gene=bmp1b\|UniProtKB=A0A8M2B1Y0	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-060818-1\|UniProtKB=Q2ABP1	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000014917.1\|UniProtKB=W5NCL2	lepisosteus oculatus	O
HUMAN\|HGNC=11844\|UniProtKB=Q9Y6L7	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000002795.5\|UniProtKB=A0A2I3SUG7	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000015595.3\|UniProtKB=G3RHU0	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000015826.4\|UniProtKB=F7CEL9	Macaca mulatta	O
MOUSE\|MGI=MGI=1346044\|UniProtKB=Q9WVM6	Mus musculus	O
RAT\|RGD=1559756\|UniProtKB=F1M280	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000011743.5\|UniProtKB=F1MF35	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000010507.4\|UniProtKB=A0A287AKC2	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000014145.4\|UniProtKB=F7DMD5	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000007143.6\|UniProtKB=M3W770	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845027238.1\|UniProtKB=A0A8I3PS39	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000004648.4\|UniProtKB=A0A5F8GLD1	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000037364.1\|UniProtKB=A0A6I8PC25	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010021803.1\|UniProtKB=A0A8V0ZF88	Gallus gallus	O
LEPOC\|Ensembl=ENSLOCG00000011225.1\|UniProtKB=W5MZJ6	lepisosteus oculatus	O
HUMAN\|HGNC=11843\|UniProtKB=O43897	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000016577.4\|UniProtKB=A0A2I3RMG2	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000000148.3\|UniProtKB=G3QD43	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000015799.4\|UniProtKB=A0A1D5QYV0	Macaca mulatta	LDO
MOUSE\|MGI=MGI=106923\|UniProtKB=Q62381	Mus musculus	LDO
RAT\|RGD=1306120\|UniProtKB=D3Z8U5	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000005968.6\|UniProtKB=F1N0X6	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000008853.5\|UniProtKB=A0A287B8G9	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000002251.3\|UniProtKB=A0A9L0TH98	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000013188.6\|UniProtKB=M3WID7	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845007341.1\|UniProtKB=A0A8I3N838	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000002435.4\|UniProtKB=F7DZV7	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000014482.3\|UniProtKB=F6WCA9	Ornithorhynchus anatinus	LDO
CHICK\|Gene=TLL1\|UniProtKB=Q9DER7	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000000252.4\|UniProtKB=H9G3K1	Anolis carolinensis	LDO
ORYLA\|Ensembl=ENSORLG00000008008.2\|UniProtKB=A0A3B3HJM6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-041020-1\|UniProtKB=O57460	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000003509.1\|UniProtKB=W5M705	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000003765.3\|UniProtKB=F6TIJ9	Ciona intestinalis	LDO
STRPU\|EnsemblGenome=GeneID_373360\|UniProtKB=P98069	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00003555\|UniProtKB=Q20176	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG16363\|UniProtKB=A8XNL6	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00097160\|UniProtKB=A0A8R1U626	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0003719\|UniProtKB=P25723	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0004885\|UniProtKB=Q9VC47	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP003702\|UniProtKB=A0A1S4GIU3	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC034615\|UniProtKB=A0A139WL18	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_204203\|UniProtKB=E9HQF5	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW016865\|UniProtKB=B7P9W0	Ixodes scapularis	LDO
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g81453\|UniProtKB=A7RH94	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g1679\|UniProtKB=A7SYW4	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g118469\|UniProtKB=A7SHE2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g166027\|UniProtKB=A7S3J5	Nematostella vectensis	LDO
PHANO\|Gene_ORFName=SNOG_04911\|UniProtKB=Q0UTK3	Phaeosphaeria nodorum	O
USTMA\|EnsemblGenome=UMAG_04092\|UniProtKB=A0A0D1DZX1	Ustilago maydis	O
PARTE\|EnsemblGenome=GSPATT00015059001\|UniProtKB=A0DAT5	Paramecium tetraurelia	O
PHYRM\|Gene=H3GL07_PHYRM\|UniProtKB=H3GL07	Phytophthora ramorum	O
PHYRM\|Gene=H3GKY7_PHYRM\|UniProtKB=H3GKY7	Phytophthora ramorum	O