PANTHER Gene Information

Gene Symbol(s):

TRIM27

Organism:

Equus caballus

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Gene Name:

RING-type E3 ubiquitin transferase

Gene ID:

ENSECAG00000019089.4

Protein ID:

A0A3Q2LKZ6

Persistent Id:

PTN001535510

Alternate Ids:

ENSECAP00000042216(Ensembl_PRO)	ENSECAG00000019089(Ensembl)
ENSECAT00000033299(Ensembl_TRS)	A0A3Q2LKZ6(Synonym)
A0A3Q2LKZ6_HORSE(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	E3 UBIQUITIN-PROTEIN LIGASE TRIM (PTHR24103)
PANTHER Subfamily:	ZINC FINGER PROTEIN RFP (PTHR24103:SF362)
PANTHER GO-slim Molecular Function:	ubiquitin protein ligase activity
PANTHER GO-slim Biological Process:	protein K63-linked ubiquitination innate immune response negative regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	ubiquitin-protein ligase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ubiquitin-protein transferase activity, zinc ion binding, identical protein binding, ubiquitin protein ligase activity, transcription coactivator activity, metal ion binding
GO BP Complete:	negative regulation of type I interferon production, negative regulation of gene expression, epigenetic, retrograde transport, endosome to Golgi, negative regulation of calcium ion import, negative regulation of transcription by RNA polymerase II, negative regulation of adaptive immune response, negative regulation of interleukin-2 production, positive regulation of DNA-templated transcription, negative regulation of autophagy, innate immune response, positive regulation of type II interferon production, Arp2/3 complex-mediated actin nucleation, protein K63-linked ubiquitination, negative regulation of tumor necrosis factor production, negative regulation of viral transcription
GO CC Complete:	nucleus, nuclear membrane, endosome, cytoplasm, retromer complex, cytosol, nucleolus, fibrillar center, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9975\|UniProtKB=P14373	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000017883.6\|UniProtKB=H2QSK5	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015891.3\|UniProtKB=G3RIJ4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000015961.4\|UniProtKB=A0A1D5QSL3	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97904\|UniProtKB=Q62158	Mus musculus	LDO
RAT\|RGD=1310105\|UniProtKB=B5DFI5	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000000871.6\|UniProtKB=Q1LZA9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000001219.6\|UniProtKB=K7GKN4	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000026440.4\|UniProtKB=M3X5V5	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845017678.1\|UniProtKB=A0A8I3NT59	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000009182.3\|UniProtKB=F7ACZ5	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000003934.4\|UniProtKB=F7GIS6	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000050924.1\|UniProtKB=A0A6I8N5Q7	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010002768.1\|UniProtKB=A0A8V0XI42	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010002784.1\|UniProtKB=A0A8V0XBF7	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010002628.1\|UniProtKB=A0A8V0X6T5	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010027264.1\|UniProtKB=A0A8V1AFN9	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010002722.1\|UniProtKB=A0A8V0XE61	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000011998.4\|UniProtKB=G1KLQ7	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000011919.4\|UniProtKB=G1KLP5	Anolis carolinensis	O
XENLA\|Gene=trim39.L\|UniProtKB=A0A8J0UEL2	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000033046\|UniProtKB=A0A6I8PYP2	Xenopus tropicalis	O
XENTR\|Gene=LOC100485004\|UniProtKB=A0A8J0S8I5	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000010091.2\|UniProtKB=A0A3B3HUM7	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000002362.1\|UniProtKB=W5M312	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000004655.2\|UniProtKB=H2LIM7	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000006807.1\|UniProtKB=W5MIL5	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000006435.1\|UniProtKB=W5MHB7	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000001822.2\|UniProtKB=A0A3B3HPF7	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000013830.1\|UniProtKB=W5N8U6	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000025756.1\|UniProtKB=A0A3B3HJB7	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000001380.1\|UniProtKB=W5LZP8	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000018910.2\|UniProtKB=H2MXD6	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000003109.1\|UniProtKB=W5M5K6	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000018411.2\|UniProtKB=H2MW28	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000010718.2\|UniProtKB=H2M4R5	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000002209.2\|UniProtKB=A0A3B3H995	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000003985.2\|UniProtKB=H2LG90	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000008015.2\|UniProtKB=H2LVC5	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000010098.2\|UniProtKB=A0A3B3HZ46	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-110921-1\|UniProtKB=A0A1D5NS95	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-060825-109\|UniProtKB=A0A1D5NS27	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000009905.1\|UniProtKB=W5MUQ4	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000002915.1\|UniProtKB=W5M4X3	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000003645.1\|UniProtKB=W5M7J2	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000017311.1\|UniProtKB=W5NLA7	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000017938.1\|UniProtKB=W5NN32	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000001322.1\|UniProtKB=W5LZE5	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000002307.1\|UniProtKB=W5M2T8	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000007198.1\|UniProtKB=W5MK20	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000009918.1\|UniProtKB=W5MUS5	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000003522.1\|UniProtKB=W5M755	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000018116.1\|UniProtKB=W5NNK8	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000002378.1\|UniProtKB=W5M344	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000009000.2\|UniProtKB=H2LYR6	Oryzias latipes	O
DANRE\|Gene=trim69\|UniProtKB=A0A8M3B6K0	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000015560.1\|UniProtKB=W5NEU4	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000015558.1\|UniProtKB=W5NEU2	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000008317.1\|UniProtKB=W5MP00	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000027741.1\|UniProtKB=A0A3B3HJV3	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000002383.2\|UniProtKB=H2LAQ3	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000022472.1\|UniProtKB=A0A3B3HRB8	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-060503-670\|UniProtKB=Q1LXQ6	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-060616-101\|UniProtKB=Q1ECU9	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000001096.2\|UniProtKB=H2L6A7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000013784.2\|UniProtKB=H2MFB5	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000004134.2\|UniProtKB=H2LGS2	Oryzias latipes	O
DANRE\|Gene=LOC101882614\|UniProtKB=A0A8M3B1M9	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-040426-1000\|UniProtKB=Q7ZU70	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000011623.1\|UniProtKB=W5N0X8	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000002075.1\|UniProtKB=W5M215	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000002063.1\|UniProtKB=W5M1Y5	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000011570.1\|UniProtKB=W5N0R0	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000005252.1\|UniProtKB=W5MD67	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000012149.1\|UniProtKB=W5N2V4	lepisosteus oculatus	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_107250\|UniProtKB=C3ZKR2	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_118421\|UniProtKB=C3ZGA6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118417355\|UniProtKB=A0A9J7MTS3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118423726\|UniProtKB=A0A9J7LSV8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118417354\|UniProtKB=A0A9J7MU30	Branchiostoma floridae	O
BRAFL\|Gene=LOC118429289\|UniProtKB=A0A9J7M7K9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118426733\|UniProtKB=A0A9J7M0M9	Branchiostoma floridae	O
CAEEL\|WormBase=WBGene00021640\|UniProtKB=Q9N3T6	Caenorhabditis elegans	O
HELRO\|EnsemblGenome=HelroG193539\|UniProtKB=T1FV38	helobdella robusta	O
DICPU\|EnsemblGenome=DICPUDRAFT_96644\|UniProtKB=F0ZA65	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_36_1550\|UniProtKB=Q4Q1S1	Leishmania major	O
PARTE\|EnsemblGenome=GSPATT00006650001\|UniProtKB=A0C977	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00019138001\|UniProtKB=A0DPI9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00002189001\|UniProtKB=A0DG93	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00005047001\|UniProtKB=A0BP31	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00004438001\|UniProtKB=A0BCS7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00027177001\|UniProtKB=A0EHR0	Paramecium tetraurelia	O