PANTHER Gene Information

Gene Symbol(s):

ABCC8

Organism:

Equus caballus

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Tree

Gene Name:

ATP binding cassette subfamily C member 8

Gene ID:

ENSECAG00000020074.4

Protein ID:

A0A5F5PIY0

Persistent Id:

PTN001542811

Alternate Ids:

ENSECAT00000073467(Ensembl_TRS)	A0A5F5PIY0_HORSE(UniProtKB-ID)
ENSECAG00000020074(Ensembl)	ENSECAP00000048463(Ensembl_PRO)
A0A5F5PIY0(Synonym)
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PANTHER Classification

PANTHER Family:	ATP-BINDING CASSETTE SUB-FAMILY C (PTHR24223)
PANTHER Subfamily:	ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8 (PTHR24223:SF187)
PANTHER GO-slim Molecular Function:	ATPase-coupled transmembrane transporter activity
PANTHER GO-slim Biological Process:	transmembrane transport
PANTHER GO-slim Cellular Component:	membrane
PANTHER protein class:	ATP-binding cassette (ABC) transporter

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ATP hydrolysis activity, ATP binding, sulfonylurea receptor activity, ATPase-coupled transmembrane transporter activity, ATPase-coupled monoatomic cation transmembrane transporter activity, ABC-type transporter activity, potassium channel activity, transmembrane transporter binding
GO BP Complete:	potassium ion transport, transmembrane transport, potassium ion transmembrane transport, monoatomic cation transmembrane transport
GO CC Complete:	inward rectifying potassium channel, membrane, protein-containing complex, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=59\|UniProtKB=Q09428	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000003403.7\|UniProtKB=H2R5J8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015972.3\|UniProtKB=G3RIT5	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000023581.4\|UniProtKB=F7HFY4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1352629\|UniProtKB=B2RUS7	Mus musculus	LDO
RAT\|RGD=3786\|UniProtKB=Q09429	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000000983.6\|UniProtKB=E1BKR6	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000013378.5\|UniProtKB=F1S9A6	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000004967.6\|UniProtKB=M3W376	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845014269.1\|UniProtKB=A0A8I3S0T4	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000006995.4\|UniProtKB=F6XVA7	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000007680.3\|UniProtKB=F6W7R8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010023276.1\|UniProtKB=A0A8V0ZVQ0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000000048.4\|UniProtKB=G1K878	Anolis carolinensis	LDO
XENLA\|Gene=LOC108713435\|UniProtKB=A0A8J1MUY3	Xenopus laevis	O
XENLA\|Gene=LOC108714951\|UniProtKB=A0A8J1KL62	Xenopus laevis	LDO
XENTR\|Ensembl=ENSXETG00000046120\|UniProtKB=A0A803JFZ7	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000016552.2\|UniProtKB=H2MPQ8	Oryzias latipes	LDO
DANRE\|Gene=abcc8b\|UniProtKB=A0A8M9P1K6	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-050517-22\|UniProtKB=F1QMZ9	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000002032.1\|UniProtKB=W5M1X2	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118405282\|UniProtKB=A0A9J7HJ97	Branchiostoma floridae	O
BRAFL\|Gene=LOC118425856\|UniProtKB=A0A9J7LYS1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118404895\|UniProtKB=A0A9J7HKR1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118428522\|UniProtKB=A0A9J7N989	Branchiostoma floridae	O
BRAFL\|Gene=LOC118429055\|UniProtKB=A0A9J7M6V0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118405793\|UniProtKB=A0A9J7HP49	Branchiostoma floridae	O
BRAFL\|Gene=LOC118406005\|UniProtKB=A0A9J7KJF0	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC581870\|UniProtKB=A0A7M7PUW3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100889760\|UniProtKB=A0A7M7T5V6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC585445\|UniProtKB=A0A7M7MYE4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105437528\|UniProtKB=A0A7M7PUP7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC586814\|UniProtKB=A0A7M7PVY3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100891765\|UniProtKB=A0A7M7NQ16	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105445458\|UniProtKB=A0A7M7N1R8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC588997\|UniProtKB=A0A7M7SSM0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100892057\|UniProtKB=A0A7M7MYV6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105439697\|UniProtKB=A0A7M7PT41	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC577854\|UniProtKB=A0A7M7MYM8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC581821\|UniProtKB=A0A7M7T5Q9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115918270\|UniProtKB=A0A7M7SSD4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=GeneID_594397\|UniProtKB=I0DHI8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC752863\|UniProtKB=A0A7M7PSZ4	Strongylocentrotus purpuratus	O
DROME\|FlyBase=FBgn0028675\|UniProtKB=Q9VL32	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP009799\|UniProtKB=A0A1S4H240	Anopheles gambiae	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_442500\|UniProtKB=E9HIJ9	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG67618\|UniProtKB=T1FZ30	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g10039\|UniProtKB=A7SMJ8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g190171\|UniProtKB=A7SII0	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG31533\|UniProtKB=B3S9C1	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG60846\|UniProtKB=B3S9B5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG60852\|UniProtKB=B3S9C0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG50946\|UniProtKB=B3S9B6	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG30988\|UniProtKB=B3S839	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG50060\|UniProtKB=B3RSQ0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG51152\|UniProtKB=B3SCI9	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_18722\|UniProtKB=A9UX43	Monosiga brevicollis	O
EMENI\|EnsemblGenome=ANIA_00015\|UniProtKB=C8VRH1	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_5G00340\|UniProtKB=Q4WDQ9	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU02051\|UniProtKB=Q7SF27	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_11032\|UniProtKB=A7F0B5	Sclerotinia sclerotiorum	O
SCLS1\|EnsemblGenome=SS1G_05336\|UniProtKB=A7EJ43	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_00757\|UniProtKB=Q0V5F7	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_08150\|UniProtKB=Q5AU80	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_07839\|UniProtKB=C8VDW5	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_5G12720\|UniProtKB=Q4WVN3	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU03776\|UniProtKB=F5HEB1	Neurospora crassa	O
EMENI\|EnsemblGenome=ANIA_07879\|UniProtKB=Q5AV01	Emericella nidulans	O
PHANO\|EnsemblGenome=SNOG_14100\|UniProtKB=Q0U1T8	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_09087\|UniProtKB=Q0UGM7	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_01240\|UniProtKB=Q5BDZ0	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G10390\|UniProtKB=Q4WT65	Neosartorya fumigata	O
SCLS1\|EnsemblGenome=SS1G_03324\|UniProtKB=A7EDD4	Sclerotinia sclerotiorum	O
SCLS1\|EnsemblGenome=SS1G_13112\|UniProtKB=A7F683	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_01112\|UniProtKB=Q0V4F2	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_14836\|UniProtKB=Q0TZX9	Phaeosphaeria nodorum	O
USTMA\|EnsemblGenome=UMAG_01758\|UniProtKB=A0A0D1CBL8	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_15074\|UniProtKB=A0A0D1CW46	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_05794\|UniProtKB=A0A0D1BZ25	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_15032\|UniProtKB=A0A0D1CSJ1	Ustilago maydis	O
YEAST\|SGD=S000003938\|UniProtKB=P14772	Saccharomyces cerevisiae	O
YEAST\|SGD=S000002542\|UniProtKB=P39109	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AGR047W\|UniProtKB=Q750B0	Eremothecium gossypii	O
CANAL\|CGD=CAL0000183742\|UniProtKB=A0A1D8PTN6	Candida albicans	O
CANAL\|CGD=CAL0000178329\|UniProtKB=Q5A762	Candida albicans	O
CANAL\|CGD=CAL0000179549\|UniProtKB=A0A1D8PR42	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_E08969g\|UniProtKB=Q6C6J9	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_F31845g\|UniProtKB=Q6BZQ2	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_A19580g\|UniProtKB=Q6CGG4	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_C18051g\|UniProtKB=Q6CBK3	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_F12089g\|UniProtKB=Q6C1Z6	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_E25069g\|UniProtKB=Q6C4N2	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_03472\|UniProtKB=Q5B7K8	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_07729\|UniProtKB=Q5AVF1	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_5G07970\|UniProtKB=Q4WUC5	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU09012\|UniProtKB=Q7S0S1	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_07453\|UniProtKB=A7EQ53	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_09278\|UniProtKB=Q0UG36	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC359.05\|UniProtKB=Q9P5N0	Schizosaccharomyces pombe	O
SCHPO\|PomBase=SPAC3F10.11c\|UniProtKB=Q10185	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_01344\|UniProtKB=B6K0F0	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNC05860\|UniProtKB=Q5KJN9	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_10365\|UniProtKB=A0A0D1DYC7	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_02568\|UniProtKB=A0A0D1E417	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_14463\|UniProtKB=E3KVN9	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_14456\|UniProtKB=E3KVN2	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_9753\|UniProtKB=F4NVY7	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_14605\|UniProtKB=F4PDI2	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_88614\|UniProtKB=F4P3J1	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_18172\|UniProtKB=F4NRK4	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_92730\|UniProtKB=F4PEH2	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_20822\|UniProtKB=F4PBV3	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_18633\|UniProtKB=F4NTL2	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_16805\|UniProtKB=F4P4C1	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_124840\|UniProtKB=C4M978	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0284867\|UniProtKB=Q54P13	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_47315\|UniProtKB=F0ZIX3	Dictyostelium purpureum	O
PARTE\|EnsemblGenome=GSPATT00001809001\|UniProtKB=A0D6V1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028165001\|UniProtKB=A0BF13	Paramecium tetraurelia	O
PHYRM\|Gene=H3HEF0_PHYRM\|UniProtKB=H3HEF0	Phytophthora ramorum	O
PHYRM\|Gene=H3HCF6_PHYRM\|UniProtKB=H3HCF6	Phytophthora ramorum	O
PHYRM\|Gene=H3HD40_PHYRM\|UniProtKB=H3HD40	Phytophthora ramorum	O
PHYRM\|Gene=H3HE07_PHYRM\|UniProtKB=H3HE07	Phytophthora ramorum	O
PHYRM\|Gene=H3GAE6_PHYRM\|UniProtKB=H3GAE6	Phytophthora ramorum	O
PHYRM\|Gene=H3HD38_PHYRM\|UniProtKB=H3HD38	Phytophthora ramorum	O
PHYRM\|Gene=H3H408_PHYRM\|UniProtKB=H3H408	Phytophthora ramorum	O
PHYRM\|Gene=H3GKM1_PHYRM\|UniProtKB=H3GKM1	Phytophthora ramorum	O
PHYRM\|Gene=H3GJD8_PHYRM\|UniProtKB=H3GJD8	Phytophthora ramorum	O
PHYRM\|Gene=H3H2W5_PHYRM\|UniProtKB=H3H2W5	Phytophthora ramorum	O
PHYRM\|Gene=H3H5U8_PHYRM\|UniProtKB=H3H5U8	Phytophthora ramorum	O
PHYRM\|Gene=H3HE89_PHYRM\|UniProtKB=H3HE89	Phytophthora ramorum	O
PHYRM\|Gene=H3GAR7_PHYRM\|UniProtKB=H3GAR7	Phytophthora ramorum	O
PHYRM\|Gene=H3G9K9_PHYRM\|UniProtKB=H3G9K9	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_08g369720v5\|UniProtKB=A0A2K3DH39	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_07g325761v5\|UniProtKB=A0A2K3DJI3	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_08g369850v5\|UniProtKB=A0A2K3DH80	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_03g174050v5\|UniProtKB=A0A2K3DX98	Chlamydomonas reinhardtii	O
KLENI\|Gene_ORFName=KFL_003420130\|UniProtKB=A0A1Y1I8H3	Klebsormidium nitens	O
CHLRE\|EnsemblGenome=CHLRE_02g097800v5\|UniProtKB=A0A2K3E226	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_17g734612v5\|UniProtKB=Q50JT7	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g564900v5\|UniProtKB=A0A2K3CZ64	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_02g103250v5\|UniProtKB=A0A2K3E2F8	Chlamydomonas reinhardtii	O
MARPO\|EnsemblGenome=MARPO_0133s0051\|UniProtKB=A0A2R6W7S7	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_004930030\|UniProtKB=A0A1Y1IDX7	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000850340\|UniProtKB=A0A1Y1I0J0	Klebsormidium nitens	O