PANTHER Gene Information

Gene Symbol(s):

SGSM3

Organism:

Equus caballus

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Gene Name:

RUN and TBC1 domain-containing protein 3

Gene ID:

ENSECAG00000022296.4

Protein ID:

F7AXJ3

Persistent Id:

PTN001490675

Alternate Ids:

ENSECAP00000019985(Ensembl_PRO)	F7AXJ3(Synonym)
ENSECAT00000024077(Ensembl_TRS)	ENSECAG00000022296(Ensembl)
F7AXJ3_HORSE(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN (PTHR22957)
PANTHER Subfamily:	SMALL G PROTEIN SIGNALING MODULATOR 3 (PTHR22957:SF681)
PANTHER GO-slim Molecular Function:	GTPase activator activity
PANTHER GO-slim Biological Process:	activation of GTPase activity
PANTHER GO-slim Cellular Component:
PANTHER protein class:	GTPase-activating protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	GTPase activator activity, small GTPase binding
GO BP Complete:	regulation of Rab protein signal transduction, positive regulation of protein catabolic process, plasma membrane to endosome transport, Rap protein signal transduction
GO CC Complete:	gap junction, cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=25228\|UniProtKB=Q96HU1	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000014408.7\|UniProtKB=H2QLR4	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015169.3\|UniProtKB=G3RGQ0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000008135.4\|UniProtKB=G7N3X5	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1916329\|UniProtKB=Q8VCZ6	Mus musculus	LDO
RAT\|RGD=735113\|UniProtKB=Q6P6R7	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000009624\|UniProtKB=Q2KI13	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000000076.4\|UniProtKB=I3LKE4	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000004800.6\|UniProtKB=A0A337SX94	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845020097.1\|UniProtKB=A0A8I3S497	Canis lupus familiaris	LDO
ORNAN\|Ensembl=ENSOANG00000008380.4\|UniProtKB=F6XN56	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000005430.4\|UniProtKB=G1KE59	Anolis carolinensis	LDO
ORYLA\|Ensembl=ENSORLG00000010788.2\|UniProtKB=A0A3B3HBF6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-2635\|UniProtKB=Q7T2D0	Danio rerio	LDO
CAEEL\|WormBase=WBGene00018281\|UniProtKB=Q94222	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG22756\|UniProtKB=A8Y337	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00099809\|UniProtKB=A0A2A6D298	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0038304\|UniProtKB=Q9VFB6	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP002120\|UniProtKB=Q7PYV2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC005163\|UniProtKB=D6W7G3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_305647\|UniProtKB=E9FX35	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW016261\|UniProtKB=B7P0S7	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG113708\|UniProtKB=T1EFV5	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g191391\|UniProtKB=A7SMP1	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG20607\|UniProtKB=B3RPU2	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_28750\|UniProtKB=A9V930	Monosiga brevicollis	LDO
YARLI\|EnsemblGenome=YALI0_A18700g\|UniProtKB=Q6CGJ8	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_00573\|UniProtKB=Q5BFV7	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_6G11220\|UniProtKB=Q4WM46	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU03330\|UniProtKB=Q1K4P9	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_09482\|UniProtKB=A7EVX3	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_06860\|UniProtKB=Q0UN04	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC4G8.04\|UniProtKB=Q09830	Schizosaccharomyces pombe	LDO
CRYNJ\|EnsemblGenome=CND01110\|UniProtKB=Q5KJ04	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_01469\|UniProtKB=A0A0D1E2A6	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_16866\|UniProtKB=E3L3J6	Puccinia graminis	LDO
PUCGT\|EnsemblGenome=PGTG_21203\|UniProtKB=H6QQJ6	Puccinia graminis	LDO
DICDI\|dictyBase=DDB_G0275421\|UniProtKB=Q553U1	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_147294\|UniProtKB=F0Z849	Dictyostelium purpureum	LDO
DICDI\|dictyBase=DDB_G0276119\|UniProtKB=Q75JG4	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_158827\|UniProtKB=F1A2L1	Dictyostelium purpureum	O
PLAF7\|EnsemblGenome=PF3D7_0506700\|UniProtKB=Q8I435	Plasmodium falciparum	LDO
PHYRM\|Gene=H3HDG5_PHYRM\|UniProtKB=H3HDG5	Phytophthora ramorum	LDO