PANTHER Gene Information

Gene Symbol(s):

KHK

Organism:

Equus caballus

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Gene Name:

Ketohexokinase

Gene ID:

ENSECAG00000025017.4

Protein ID:

A0A3Q2IAG0

Persistent Id:

PTN001317402

Alternate Ids:

ENSECAP00000044514(Ensembl_PRO)	100055449(GeneID)
A0A3Q2IAG0(Synonym)	ENSECAT00000039658(Ensembl_TRS)
149727694(GI)	ENSECAG00000025017(Ensembl)
A0A3Q2IAG0_HORSE(UniProtKB-ID)	XM_001502538(refSeq)
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PANTHER Classification

PANTHER Family:	HEXOKINASE FAMILY MEMBER (PTHR43085)
PANTHER Subfamily:	KETOHEXOKINASE (PTHR43085:SF55)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	carbohydrate kinase

Pathway Categories:

Fructose galactose metabolism

Ketohexokinase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ATP binding, identical protein binding, fructose binding, protein homodimerization activity, ketohexokinase activity
GO BP Complete:	response to glucose, response to zinc ion, response to insulin, response to fructose, fructose metabolic process, regulation of glycogen metabolic process, carbohydrate phosphorylation, phosphate-containing compound metabolic process, response to sucrose
GO CC Complete:	cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6315\|UniProtKB=P50053	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000011746.5\|UniProtKB=H2QHL3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000002595.3\|UniProtKB=A0A2I2ZK23	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=1096353\|UniProtKB=P97328	Mus musculus	LDO
RAT\|RGD=2966\|UniProtKB=Q02974	Rattus norvegicus	LDO
FELCA\|Ensembl=ENSFCAG00000009886.5\|UniProtKB=A0A2I2U2F8	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000015726.3\|UniProtKB=A0A5F8GPE3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000000509.3\|UniProtKB=F7CVJ4	Ornithorhynchus anatinus	LDO
ORYLA\|Ensembl=ENSORLG00000013091.2\|UniProtKB=H2MCX1	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000015943.1\|UniProtKB=W5NG72	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004329.3\|UniProtKB=F7BN93	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_219293\|UniProtKB=C3Y1K0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409679\|UniProtKB=A0A9J7KMJ7	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC588197\|UniProtKB=A0A7M7RGI9	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0036161\|UniProtKB=Q8T4I0	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0036160\|UniProtKB=Q9VTI3	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0036941\|UniProtKB=Q9VW82	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0036942\|UniProtKB=Q9VW84	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP002483\|UniProtKB=Q5TTS3	Anopheles gambiae	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_213561\|UniProtKB=E9GTM4	Daphnia pulex	LDO
TRIAD\|EnsemblGenome=TriadG58015\|UniProtKB=B3S2G3	Trichoplax adhaerens	LDO
EMENI\|EnsemblGenome=ANIA_10054\|UniProtKB=C8VTZ4	Emericella nidulans	LDO
NEUCR\|EnsemblGenome=NCU03742\|UniProtKB=V5IMP9	Neurospora crassa	LDO
DICDI\|dictyBase=DDB_G0292440\|UniProtKB=Q54D80	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_39975\|UniProtKB=F0ZXC3	Dictyostelium purpureum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_156747\|UniProtKB=F0ZXC0	Dictyostelium purpureum	LDO
PYRAE\|EnsemblGenome=PAE3318\|UniProtKB=Q8ZTC9	Pyrobaculum aerophilum	LDO
METAC\|EnsemblGenome=MA_3267\|UniProtKB=Q8TKX6	Methanosarcina acetivorans	LDO
THEMA\|EnsemblGenome=TM_0415\|UniProtKB=Q9WYP6	Thermotoga maritima	O
BACTN\|EnsemblGenome=BT_3576\|UniProtKB=Q8A1T2	Bacteroides thetaiotaomicron	O
STRCO\|Gene_OrderedLocusName=SCO6978\|UniProtKB=Q9KZH4	Streptomyces coelicolor	O
LISMO\|EnsemblGenome=CAC98464\|UniProtKB=Q8Y9Y2	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_39740\|UniProtKB=P42414	Bacillus subtilis	O
CHLAA\|EnsemblGenome=Caur_3023\|UniProtKB=A9WGQ6	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO2158\|UniProtKB=Q9X816	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv2202c\|UniProtKB=P9WID5	Mycobacterium tuberculosis	O
CHLAA\|EnsemblGenome=Caur_1424\|UniProtKB=A9WA93	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_2881\|UniProtKB=A9WF96	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO1957\|UniProtKB=Q9Z508	Streptomyces coelicolor	O
CLOBH\|Gene_OrderedLocusName=CBO1168\|UniProtKB=A5I108	Clostridium botulinum	O
CLOBH\|Gene_OrderedLocusName=CBO1769\|UniProtKB=A5I2P1	Clostridium botulinum	O
STAA8\|EnsemblGenome=SAOUHSC_00291\|UniProtKB=Q2G164	Staphylococcus aureus	O
STAA8\|EnsemblGenome=SAOUHSC_02267\|UniProtKB=Q2FWM2	Staphylococcus aureus	O
BACSU\|EnsemblGenome=BSU_06170\|UniProtKB=O34768	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_0773\|UniProtKB=Q81HN1	Bacillus cereus	O
THEMA\|EnsemblGenome=TM_0296\|UniProtKB=Q9WYD2	Thermotoga maritima	O
DEIRA\|EnsemblGenome=DR_0728\|UniProtKB=Q9RWE1	Deinococcus radiodurans	O
GLOVI\|Gene=Q7NNA9_GLOVI\|UniProtKB=Q7NNA9	Gloeobacter violaceus	O
SYNY3\|Gene=cscK\|UniProtKB=P73521	Synechocystis	O
RHOBA\|EnsemblGenome=RB5198\|UniProtKB=Q7UGI5	Rhodopirellula baltica	O
SALTY\|EnsemblGenome=STM3251\|UniProtKB=Q8ZLV6	Salmonella typhimurium	O
DICTD\|EnsemblGenome=Dtur_0388\|UniProtKB=B8DZ66	Dictyoglomus turgidum	O
DICTD\|EnsemblGenome=Dtur_0795\|UniProtKB=B8DZZ3	Dictyoglomus turgidum	O
BRADU\|Gene=kdgK\|UniProtKB=Q89NC0	Bradyrhizobium diazoefficiens	O
COXBU\|EnsemblGenome=CBU_1223\|UniProtKB=Q83CA5	Coxiella burnetii	O
HAEIN\|EnsemblGenome=HI_0049\|UniProtKB=P44482	Haemophilus influenzae	O
SALTY\|EnsemblGenome=STM3612\|UniProtKB=Q8ZLC0	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO3990\|UniProtKB=A0A3N4B6X2	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA15563\|UniProtKB=P77493	Escherichia coli	O
ECOLI\|EnsemblGenome=BAE77768\|UniProtKB=P37647	Escherichia coli	O
SHEON\|Gene_OrderedLocusName=SO_2020\|UniProtKB=Q8EFF3	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_A0801\|UniProtKB=Q9KLE5	Vibrio cholerae	O
VIBCH\|EnsemblGenome=VC_1129\|UniProtKB=Q9KSX7	Vibrio cholerae	O
SALTY\|EnsemblGenome=STM0491\|UniProtKB=Q8ZRA0	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO3095\|UniProtKB=A0A3N4B1Y6	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE76256\|UniProtKB=P0AEW6	Escherichia coli	O
SHEON\|Gene_OrderedLocusName=SO_4458\|UniProtKB=Q8E935	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_A0656\|UniProtKB=Q9KLT5	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC1509\|UniProtKB=Q8PAH4	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA2344\|UniProtKB=Q9I1D4	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM3600\|UniProtKB=Q8ZLD1	Salmonella typhimurium	O
ECOLI\|EnsemblGenome=BAE77917\|UniProtKB=P45543	Escherichia coli	O
SALTY\|EnsemblGenome=STM4066\|UniProtKB=Q8ZKR2	Salmonella typhimurium	O
ECOLI\|EnsemblGenome=BAA15968\|UniProtKB=P76419	Escherichia coli	O