PANTHER Gene Information

Gene Symbol(s):

TRIM48

Organism:

Homo sapiens

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Gene Name:

E3 ubiquitin-protein ligase TRIM48

Gene ID:

HGNC:19021

Protein ID:

Q8IWZ4

Enhancers:

View enhancers for HUMAN|HGNC=19021|UniProtKB=Q8IWZ4

Genetic Variant Annotation:

Annoq

Persistent Id:

PTN002541822

Alternate Ids:

AAO14946(EMBL-CDS)	119594076(GI)
TRI48_HUMAN(UniProtKB-ID)	BC001862(EMBL)
TRIM48{ECO:0000312\|HGNC:HGNC:19021}(Symbol)	ENST00000417545(Ensembl_TRS)
ENSP00000402414(Ensembl_PRO)	TRI48(Synonym)
79097(GeneID)	HGNC:19021(HGNC)
NM_024114(refSeq)	Q9BUW4(AltAccession)
ENSG00000150244(Ensembl)	2.3.2.27 {ECO:0000269\|PubMed:29186683}(EC)
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PANTHER Classification

PANTHER Family:	E3 UBIQUITIN-PROTEIN LIGASE TRIM (PTHR24103)
PANTHER Subfamily:	E3 UBIQUITIN-PROTEIN LIGASE TRIM48 (PTHR24103:SF632)
PANTHER GO-slim Molecular Function:	ubiquitin protein ligase activity
PANTHER GO-slim Biological Process:	protein ubiquitination innate immune response regulation of gene expression
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	ubiquitin-protein ligase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	zinc ion binding, ubiquitin protein ligase activity, protein binding
GO BP Complete:	innate immune response, regulation of gene expression
GO CC Complete:	cytoplasm, cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Cytokine Signaling in Immune system, Immune System, Interferon gamma signaling, Interferon Signaling

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000048980.1\|UniProtKB=A0A2I3RSA6	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000052546.1\|UniProtKB=H2Q4J2	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000041395.1\|UniProtKB=G3QYJ6	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000051175.1\|UniProtKB=F7G6U8	Macaca mulatta	LDO
BOVIN\|Ensembl=ENSBTAG00000054977.1\|UniProtKB=A0A3Q1MI30	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000046061.1\|UniProtKB=A0A5G2R0J5	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000049020.1\|UniProtKB=A0A5G2QHU7	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000019401.4\|UniProtKB=F7E2N4	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000049822.1\|UniProtKB=A0A5F5XVC6	Felis catus	O
FELCA\|Ensembl=ENSFCAG00000043585.2\|UniProtKB=A0A5F5XCL1	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845024803.1\|UniProtKB=A0A8I3S8W6	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845025158.1\|UniProtKB=A0A8I3PKB5	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000039692.1\|UniProtKB=A0A5F8GSI3	Monodelphis domestica	O
CHICK\|Ensembl=ENSGALG00010029560.1\|UniProtKB=A0A8V1AP69	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000025926.3\|UniProtKB=G1KUV1	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000014928.4\|UniProtKB=H9GLQ3	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000017237.3\|UniProtKB=H9GP47	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000011368.4\|UniProtKB=G1KL65	Anolis carolinensis	O
ORYLA\|Ensembl=ENSORLG00000007167.2\|UniProtKB=H2LSC7	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-060825-228\|UniProtKB=F1Q977	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000009030.1\|UniProtKB=W5MRJ6	lepisosteus oculatus	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_107250\|UniProtKB=C3ZKR2	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_118421\|UniProtKB=C3ZGA6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118417355\|UniProtKB=A0A9J7MTS3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118423726\|UniProtKB=A0A9J7LSV8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118417354\|UniProtKB=A0A9J7MU30	Branchiostoma floridae	O
BRAFL\|Gene=LOC118429289\|UniProtKB=A0A9J7M7K9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118426733\|UniProtKB=A0A9J7M0M9	Branchiostoma floridae	O
CAEEL\|WormBase=WBGene00021640\|UniProtKB=Q9N3T6	Caenorhabditis elegans	O
HELRO\|EnsemblGenome=HelroG193539\|UniProtKB=T1FV38	helobdella robusta	O
DICPU\|EnsemblGenome=DICPUDRAFT_96644\|UniProtKB=F0ZA65	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_36_1550\|UniProtKB=Q4Q1S1	Leishmania major	O
PARTE\|EnsemblGenome=GSPATT00006650001\|UniProtKB=A0C977	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00019138001\|UniProtKB=A0DPI9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00002189001\|UniProtKB=A0DG93	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00005047001\|UniProtKB=A0BP31	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00004438001\|UniProtKB=A0BCS7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00027177001\|UniProtKB=A0EHR0	Paramecium tetraurelia	O