PANTHER Gene Information

Gene Symbol(s):

CACNA2D4

Organism:

Homo sapiens

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Gene Name:

Voltage-dependent calcium channel subunit alpha-2_delta-4

Gene ID:

HGNC:20202

Protein ID:

Q7Z3S7

Enhancers:

View enhancers for HUMAN|HGNC=20202|UniProtKB=Q7Z3S7

Genetic Variant Annotation:

Annoq

Persistent Id:

PTN002468550

Alternate Ids:

AAN06672(EMBL-CDS)	CHEMBL2363032(ChEMBL)
Q8IZS9(AltAccession)	AC005343(EMBL)
CACNA2D4(Symbol)	Voltage-gated calcium channel subunit alpha-2/delta-4(Synonym)
ENSG00000151062(Ensembl)	CA2D4_HUMAN(UniProtKB-ID)
93589(GeneID)	22770594(GI)
610478(MIM)	HGNC:20202(HGNC)
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PANTHER Classification

PANTHER Family:	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED (PTHR10166)
PANTHER Subfamily:	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-4 (PTHR10166:SF59)
PANTHER GO-slim Molecular Function:	voltage-gated calcium channel activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	voltage-gated calcium channel complex
PANTHER protein class:	voltage-gated ion channel

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	metal ion binding, voltage-gated calcium channel activity
GO BP Complete:	detection of light stimulus involved in visual perception, calcium ion transmembrane transport
GO CC Complete:	voltage-gated calcium channel complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000004521.7\|UniProtKB=A0A2I3S6D0	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010619.3\|UniProtKB=G3R511	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000017265.4\|UniProtKB=F7GWV8	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2442632\|UniProtKB=Q5RJF7	Mus musculus	LDO
RAT\|RGD=1562038\|UniProtKB=D3ZM84	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000021994.6\|UniProtKB=A0A3Q1M6F5	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000026537.4\|UniProtKB=I3LD16	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000022862.4\|UniProtKB=A0A9L0R1K7	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000031264.4\|UniProtKB=A0A2I2UBV9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845029753.1\|UniProtKB=A0A8I3Q9I2	Canis lupus familiaris	LDO
ORNAN\|Ensembl=ENSOANG00000008855.3\|UniProtKB=F7FJ02	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010013942.1\|UniProtKB=A0A8V0YMA3	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000010899.4\|UniProtKB=G1KKS4	Anolis carolinensis	LDO
XENLA\|Gene=LOC108704584\|UniProtKB=A0A8J1MKD1	Xenopus laevis	LDO
XENTR\|Gene=cacna2d4\|UniProtKB=A0A8J1J9C0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000000721.2\|UniProtKB=H2L530	Oryzias latipes	LDO
ORYLA\|Ensembl=ENSORLG00000013968.2\|UniProtKB=H2MFZ3	Oryzias latipes	O
DANRE\|Gene=cacna2d4b\|UniProtKB=A0A8M3AZP4	Danio rerio	O
DANRE\|Gene=cacna2d4a\|UniProtKB=A0A8M9QBV8	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000016631.1\|UniProtKB=W5NIU3	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000022683.1\|UniProtKB=H2XL54	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000013789.2\|UniProtKB=F6REB5	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118423137\|UniProtKB=A0A9J7N263	Branchiostoma floridae	O
BRAFL\|Gene=LOC118415148\|UniProtKB=A0A9J7MQA4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC100890679\|UniProtKB=A0A7M7GKH8	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00007041\|UniProtKB=G5EG74	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG02926\|UniProtKB=A8WT73	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00278310\|UniProtKB=A0A2A6BZ90	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00006772\|UniProtKB=P34374	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG16666\|UniProtKB=A8XP97	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00096769\|UniProtKB=A0A2A6CBK0	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0028863\|UniProtKB=X2J9Z3	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP009598\|UniProtKB=A0A903XHE3	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC001887\|UniProtKB=A0A139WP66	Tribolium castaneum	LDO
DROME\|FlyBase=FBgn0261999\|UniProtKB=Q8IP22	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP009579\|UniProtKB=A0A1S4H1J5	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC004591\|UniProtKB=D6W834	Tribolium castaneum	O
DROME\|FlyBase=FBgn0261041\|UniProtKB=A0A0B4K866	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP005490\|UniProtKB=A0A1S4GQ08	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC008265\|UniProtKB=D2A0T3	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC034736\|UniProtKB=A0A139WGS5	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_324542\|UniProtKB=E9H214	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_317041\|UniProtKB=E9GER3	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG174990\|UniProtKB=T1F8P7	helobdella robusta	LDO
TRIAD\|EnsemblGenome=TriadG56910\|UniProtKB=B3RWW7	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG56917\|UniProtKB=B3RWX4	Trichoplax adhaerens	LDO
EMENI\|EnsemblGenome=ANIA_05167\|UniProtKB=Q5B2R3	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_6G06990\|UniProtKB=Q4WNB0	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU07565\|UniProtKB=Q7S1Y8	Neurospora crassa	LDO
SELML\|EnsemblGenome=SELMODRAFT_423100\|UniProtKB=D8SKK3	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_402207\|UniProtKB=D8QPX5	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_423098\|UniProtKB=D8SKK1	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_402199\|UniProtKB=D8QPW7	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_423092\|UniProtKB=D8SKJ4	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_402200\|UniProtKB=D8QPW8	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_402202\|UniProtKB=D8QPX0	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c1_25930\|UniProtKB=A0A2K1L9Q7	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c10_3200\|UniProtKB=A0A2K1JXH6	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c2_5170\|UniProtKB=A0A2K1L0A2	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c7_20720\|UniProtKB=A0A2K1KCD4	Physcomitrella patens	LDO
PHYPA\|EnsemblGenome=Pp3c7_19620\|UniProtKB=A0A2K1KC88	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c20_5240\|UniProtKB=A0A2K1IU47	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c22_5320\|UniProtKB=A0A2K1IMC0	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c17_14540\|UniProtKB=A0A7I4B6P4	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0123s0041\|UniProtKB=A0A2R6W9N0	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0009s0226\|UniProtKB=A0A2R6XM14	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0110s0042\|UniProtKB=A0A2R6WCH7	Marchantia polymorpha	LDO
MARPO\|EnsemblGenome=MARPO_0123s0042\|UniProtKB=A0A2R6W9N1	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0009s0220\|UniProtKB=A0A2R6XM18	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0200s0010\|UniProtKB=A0A2R6W0N0	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_006550030\|UniProtKB=A0A1Y1IIM7	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_006550020\|UniProtKB=A0A1Y1IKA2	Klebsormidium nitens	LDO
STRCO\|Gene_OrderedLocusName=SCO2721\|UniProtKB=Q9L1J5	Streptomyces coelicolor	LDO
CLOBH\|Gene_OrderedLocusName=CBO3213\|UniProtKB=A5I6U2	Clostridium botulinum	O
CLOBH\|Gene_OrderedLocusName=CBO0552\|UniProtKB=A5HZ97	Clostridium botulinum	LDO
BACTN\|EnsemblGenome=BT_4465\|UniProtKB=Q89ZB2	Bacteroides thetaiotaomicron	LDO
RHOBA\|EnsemblGenome=RB7099\|UniProtKB=Q7UP85	Rhodopirellula baltica	LDO
SHEON\|Gene_OrderedLocusName=SO_3552\|UniProtKB=Q8EBG6	Shewanella oneidensis	LDO
XANCP\|EnsemblGenome=XCC2915\|UniProtKB=Q8P6Q2	Xanthomonas campestris	LDO
SALTY\|EnsemblGenome=STM2315\|UniProtKB=Q8ZNE5	Salmonella typhimurium	LDO
ECOLI\|EnsemblGenome=BAE76678\|UniProtKB=P76481	Escherichia coli	LDO