PANTHER Gene Information

Gene Symbol(s):

FBXL20

Organism:

Homo sapiens

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Gene Name:

F-box_LRR-repeat protein 20

Gene ID:

HGNC:24679

Protein ID:

Q96IG2

Enhancers:

View enhancers for HUMAN|HGNC=24679|UniProtKB=Q96IG2

Genetic Variant Annotation:

Annoq

Persistent Id:

PTN002541199

Alternate Ids:

158257120(GI)	F-box/LRR-repeat protein 2-like(Synonym)
FXL20_HUMAN(UniProtKB-ID)	A8K729(AltAccession)
HGNC:24679(HGNC)	609086(MIM)
FBXL20(Symbol)	84961(GeneID)
ABB03906(EMBL-CDS)	DQ223959(EMBL)
ENSG00000108306(Ensembl)
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PANTHER Classification

PANTHER Family:	PARTNER OF PAIRED, ISOFORM B-RELATED (PTHR13318)
PANTHER Subfamily:	F-BOX_LRR-REPEAT PROTEIN 20 (PTHR13318:SF47)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
PANTHER GO-slim Cellular Component:	SCF ubiquitin ligase complex
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	protein binding
GO BP Complete:	regulation of protein catabolic process at presynapse, modulating synaptic transmission, regulation of synaptic vesicle exocytosis, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, behavioral fear response
GO CC Complete:	Schaffer collateral - CA1 synapse, presynapse, cytosol, SCF ubiquitin ligase complex, glutamatergic synapse

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Metabolism of proteins, Immune System, Adaptive Immune System, Neddylation, Antigen processing: Ubiquitination & Proteasome degradation, Post-translational protein modification, Class I MHC mediated antigen processing & presentation

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000009090.6\|UniProtKB=H2QCU2	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000009694.3\|UniProtKB=A0A2I2ZFC9	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=1919444\|UniProtKB=Q9CZV8	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000008371\|UniProtKB=Q58DG6	Bos taurus	LDO
HORSE\|Ensembl=ENSECAG00000016061.4\|UniProtKB=A0A9L0TR23	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000014617.6\|UniProtKB=A0A337S8T2	Felis catus	LDO
ANOCA\|Ensembl=ENSACAG00000017505.4\|UniProtKB=R4GAT7	Anolis carolinensis	LDO
ORYLA\|Ensembl=ENSORLG00000003477.2\|UniProtKB=H2LEF5	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-081031-27\|UniProtKB=B8K0E7	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000012778.1\|UniProtKB=W5N518	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004763.3\|UniProtKB=A0A1W2WIN8	Ciona intestinalis	O
BRAFL\|Gene=LOC118403897\|UniProtKB=A0A9J7HFD5	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC754350\|UniProtKB=A0A7M7G0Z8	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00015350\|UniProtKB=P34284	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00036539\|UniProtKB=A8XP90	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00284722\|UniProtKB=A0A2A6CDR7	Pristionchus pacificus	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_305732\|UniProtKB=E9FXY3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_305779\|UniProtKB=E9GSE1	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW000110\|UniProtKB=B7P7F0	Ixodes scapularis	O
DROME\|FlyBase=FBgn0033639\|UniProtKB=A8DYA6	Drosophila melanogaster	O
TRICA\|EnsemblGenome=TC013252\|UniProtKB=A0A139WHE4	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_315868\|UniProtKB=E9GB33	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW014887\|UniProtKB=B7QHI2	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g221452\|UniProtKB=A7T2M0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g240237\|UniProtKB=A7RRS0	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_11527\|UniProtKB=A9V9E7	Monosiga brevicollis	O
EREGS\|EnsemblGenome=AGOS_ACL088C\|UniProtKB=Q75CK7	Eremothecium gossypii	O
EMENI\|EnsemblGenome=ANIA_04237\|UniProtKB=Q5B5E3	Emericella nidulans	O
SCLS1\|Gene_ORFName=SS1G_06505\|UniProtKB=A7EMF7	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_04252\|UniProtKB=Q0UVG2	Phaeosphaeria nodorum	O
CRYNJ\|EnsemblGenome=CNL04270\|UniProtKB=Q5K8W4	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_01999\|UniProtKB=A0A0D1E426	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_00588\|UniProtKB=A0A0D1ED76	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_04345\|UniProtKB=E3K220	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_87898\|UniProtKB=F4P0M4	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_21504\|UniProtKB=F4NTH4	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_099230\|UniProtKB=C4M6B6	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_139980\|UniProtKB=C4M956	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0285177\|UniProtKB=Q54NL3	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_32869\|UniProtKB=F0ZJX1	Dictyostelium purpureum	O