PANTHER Gene Information

Gene Symbol(s):

IscW_ISCW001465

Organism:

Ixodes scapularis

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Gene Name:

Thioredoxin H2 protein, putative

Gene ID:

ISCW001465

Protein ID:

B7P2A3

Persistent Id:

PTN000824591

Alternate Ids:

ABJB010166214(EMBL)	240974878(GI)
ISCW001465-RA(Ensembl_TRS)	B7P2A3(Synonym)
EEC00725(EMBL-CDS)	ISCW001465-PA(Ensembl_PRO)
XP_002401915(refSeq)	ISCW001465(Ensembl)
B7P2A3_IXOSC(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	THIOREDOXIN-LIKE PROTEIN 1 (PTHR46115)
PANTHER Subfamily:	AT08565P (PTHR46115:SF1)
PANTHER GO-slim Molecular Function:	protein-disulfide reductase activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	cytosol
PANTHER protein class:	oxidoreductase

Pathway Categories:

Hypoxia response via HIF activation

thioredoxin

Oxidative stress response

thioredoxin

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	protein disulfide isomerase activity, protein-disulfide reductase activity, isomerase activity
GO BP Complete:	-
GO CC Complete:	cytoplasm, cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
PIG\|Ensembl=ENSSSCG00000005454.5\|UniProtKB=A0A8D1P752	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000013324.4\|UniProtKB=A0A9R8N1B8	Equus caballus	LDO
CANLF\|Ensembl=ENSCAFG00845013227.1\|UniProtKB=A0A8I3NLC3	Canis lupus familiaris	LDO
ANOCA\|Ensembl=ENSACAG00000039569.1\|UniProtKB=A0A803SXX7	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000013018.3\|UniProtKB=H9GJI5	Anolis carolinensis	LDO
XENLA\|Gene=LOC108695339\|UniProtKB=A0A8J1KPZ0	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000044227\|UniProtKB=A0A803KA02	Xenopus tropicalis	O
XENLA\|Gene=LOC108706331\|UniProtKB=A0A8J0UA65	Xenopus laevis	O
XENLA\|Gene=txn.L\|UniProtKB=Q5U566	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000036357\|UniProtKB=A0A6I8PYF7	Xenopus tropicalis	O
XENTR\|Xenbase=XB-GENE-5961764\|UniProtKB=B2RZ04	Xenopus tropicalis	O
XENTR\|Xenbase=XB-GENE-5895392\|UniProtKB=Q5XGB5	Xenopus tropicalis	O
XENLA\|Gene=XB5909790.S\|UniProtKB=Q6GQ64	Xenopus laevis	LDO
XENLA\|Gene=LOC100037235\|UniProtKB=A2VDE6	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5909791\|UniProtKB=F6ZMN7	Xenopus tropicalis	LDO
STRPU\|EnsemblGenome=LOC752709\|UniProtKB=A0A7M7PM38	Strongylocentrotus purpuratus	LDO
HUMAN\|HGNC=12436\|UniProtKB=O43396	Homo sapiens	O
GORGO\|Ensembl=ENSGGOG00000009301.3\|UniProtKB=G3S1H4	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000012915.4\|UniProtKB=I0FIJ3	Macaca mulatta	O
MOUSE\|MGI=MGI=1860078\|UniProtKB=Q8CDN6	Mus musculus	O
RAT\|RGD=621717\|UniProtKB=Q920J4	Rattus norvegicus	O
PIG\|Ensembl=ENSSSCG00000004537.5\|UniProtKB=F1S1X9	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000021822.3\|UniProtKB=F6WYZ3	Equus caballus	O
CANLF\|Ensembl=ENSCAFG00845002269.1\|UniProtKB=A0A8I3RQK7	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845002269.1\|UniProtKB=A0A8I3RQK7	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000020454.4\|UniProtKB=A0A5F8GZ63	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000001710.3\|UniProtKB=A0A6I8NQ53	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010013248.1\|UniProtKB=A0A8V0YJC5	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010010288.1\|UniProtKB=A0A8V0Y035	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000009121.4\|UniProtKB=A0A803TJ10	Anolis carolinensis	O
XENLA\|Gene=txnl1.L\|UniProtKB=Q5HZ70	Xenopus laevis	O
XENLA\|Gene=txnl1.S\|UniProtKB=Q6DDW1	Xenopus laevis	O
ORYLA\|Ensembl=ENSORLG00000015007.2\|UniProtKB=A0A3B3HCP6	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040426-701\|UniProtKB=F6NTA0	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000003581.1\|UniProtKB=W5M788	lepisosteus oculatus	O
BRAFL\|Gene=LOC118412740\|UniProtKB=A0A9J7MLJ1	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC581305\|UniProtKB=A0A7M7REX8	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00021826\|UniProtKB=G5EES9	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00035346\|UniProtKB=A8XL51	Caenorhabditis briggsae	LDO
CAEEL\|WormBase=WBGene00021933\|UniProtKB=Q9N357	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00030216\|UniProtKB=A8X6I8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00104492\|UniProtKB=A0A2A6C4X7	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0035631\|UniProtKB=Q9VRP3	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP009584\|UniProtKB=Q9NGZ1	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP005462\|UniProtKB=Q7PNL3	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC009487\|UniProtKB=D6WRJ3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_303052\|UniProtKB=E9FTZ5	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG166232\|UniProtKB=T1EXX4	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG185138\|UniProtKB=T1FMG0	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g129806\|UniProtKB=A7SSF5	Nematostella vectensis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g165919\|UniProtKB=A7S3A4	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG30625\|UniProtKB=B3S7S6	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_18559\|UniProtKB=A9UWC4	Monosiga brevicollis	LDO
CANAL\|CGD=CAL0000188904\|UniProtKB=Q5A915	Candida albicans	O
CANAL\|CGD=CAL0000180451\|UniProtKB=A0A1D8PU69	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E31647g\|UniProtKB=Q6C3W5	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_01639\|UniProtKB=Q5BCU1	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_4G09090\|UniProtKB=Q4WPF6	Neosartorya fumigata	LDO
SCLS1\|Gene_ORFName=SS1G_12852\|UniProtKB=A7F5H4	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_03783\|UniProtKB=Q0UWT1	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC577.08c\|UniProtKB=Q9USR1	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_04539\|UniProtKB=B6K736	Schizosaccharomyces japonicus	O
SCHJY\|EnsemblGenome=SJAG_00614\|UniProtKB=B6JW45	Schizosaccharomyces japonicus	O
SCHJY\|EnsemblGenome=SJAG_04953\|UniProtKB=B6K874	Schizosaccharomyces japonicus	LDO
USTMA\|EnsemblGenome=UMAG_04579\|UniProtKB=A0A0D1DUR7	Ustilago maydis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_10291\|UniProtKB=F4NXR3	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0287227\|UniProtKB=Q54KN7	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_88591\|UniProtKB=F0ZQB7	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_49331\|UniProtKB=F0ZTB2	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0276057\|UniProtKB=Q75JM6	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_76816\|UniProtKB=F0ZEQ5	Dictyostelium purpureum	LDO
TRIV3\|Gene_ORFName=TVAG_339630\|UniProtKB=A2G881	Trichomonas vaginalis	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_270230\|UniProtKB=B8BVB7	Thalassiosira pseudonana	LDO
SELML\|EnsemblGenome=SELMODRAFT_77812\|UniProtKB=D8QRC3	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_94818\|UniProtKB=D8RJH9	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c9_20570\|UniProtKB=A0A2K1K3Z8	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c15_21760\|UniProtKB=A0A2K1JE06	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0118s0007\|UniProtKB=A0A2R6WAJ1	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000460060\|UniProtKB=A0A1Y1HN79	Klebsormidium nitens	LDO
MUSAM\|EnsemblGenome=Ma11_g13840\|UniProtKB=A0A804L7L0	Musa acuminata subsp. malaccensis	O
SPIOL\|Gene=LOC110796635\|UniProtKB=A0A9R0IXL3	Spinacia oleracea	O
SPIOL\|Gene=TRXF_SPIOL\|UniProtKB=P09856	Spinacia oleracea	O
HELAN\|Gene_ORFName=HanXRQr2_Chr16g0747031\|UniProtKB=A0A9K3DSL6	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr14g0626911\|UniProtKB=A0A9K3H699	Helianthus annuus	O
KLENI\|Gene_ORFName=KFL_003690040\|UniProtKB=A0A1Y1IAS9	Klebsormidium nitens	O
MARPO\|EnsemblGenome=MARPO_0022s0042\|UniProtKB=A0A2R6XCU3	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_000030040\|UniProtKB=A0A1Y1HIN4	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_005730030\|UniProtKB=A0A0U9HLB8	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_001920150\|UniProtKB=A0A1Y1I0S7	Klebsormidium nitens	O