PANTHER Gene Information

Gene Symbol(s):

Organism:

Ixodes scapularis

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Gene Name:

Uncharacterized protein

Gene ID:

ISCW006186

Protein ID:

A0A1S4KYI2

Persistent Id:

PTN000952834

Alternate Ids:

ISCW006186-RA(Ensembl_TRS)	A0A1S4KYI2(Synonym)
ISCW006186-PA(Ensembl_PRO)	A0A1S4KYI2_IXOSC(UniProtKB-ID)
ABJB010634665(EMBL)	ISCW006186(Ensembl)
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PANTHER Classification

PANTHER Family:	SIGNAL PEPTIDE PEPTIDASE (PTHR12174)
PANTHER Subfamily:	MINOR HISTOCOMPATIBILITY ANTIGEN H13 (PTHR12174:SF23)
PANTHER GO-slim Molecular Function:	aspartic-type endopeptidase activity
PANTHER GO-slim Biological Process:	signal peptide processing membrane protein proteolysis
PANTHER GO-slim Cellular Component:	side of membrane endoplasmic reticulum membrane
PANTHER protein class:	aspartic protease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	aspartic endopeptidase activity, intramembrane cleaving
GO BP Complete:	membrane protein proteolysis, signal peptide processing
GO CC Complete:	endoplasmic reticulum membrane, lumenal side of endoplasmic reticulum membrane, cytoplasmic side of endoplasmic reticulum membrane, membrane, endoplasmic reticulum

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=16435\|UniProtKB=Q8TCT9	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000050703.1\|UniProtKB=K7BBG3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000000991.3\|UniProtKB=G3S6U2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000005119.4\|UniProtKB=F7BY21	Macaca mulatta	LDO
MOUSE\|MGI=MGI=95886\|UniProtKB=Q9D8V0	Mus musculus	LDO
RAT\|RGD=1308946\|UniProtKB=A0A8I6A6G8	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000008840.6\|UniProtKB=A0A3Q1M7Q7	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000007228.5\|UniProtKB=A0A287AIQ7	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000019217.4\|UniProtKB=A0A3Q2KKI1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000014661.6\|UniProtKB=M3WL38	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845018447.1\|UniProtKB=A0A8I3P797	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000019497.4\|UniProtKB=A0A5F8HH85	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000045828.1\|UniProtKB=A0A6I8NP97	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010014047.1\|UniProtKB=A0A8V0YPC3	Gallus gallus	LDO
XENLA\|Gene=hm13.S\|UniProtKB=A0A1L8EKD2	Xenopus laevis	O
XENLA\|Gene=hm13.L\|UniProtKB=Q7T0W7	Xenopus laevis	LDO
XENTR\|Gene=hm13\|UniProtKB=A0A8J1IW36	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000018474.2\|UniProtKB=H2MW91	Oryzias latipes	LDO
DANRE\|Gene=hm13\|UniProtKB=A0A8M2B8N4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000004095.1\|UniProtKB=W5M941	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000009763.3\|UniProtKB=Q68A31	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118410122\|UniProtKB=A0A9J7MH77	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC589801\|UniProtKB=A0A7M7NNN7	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00016378\|UniProtKB=A0A0K3AUD2	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00037239\|UniProtKB=A8XRJ7	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00011481\|UniProtKB=P49049	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00028359\|UniProtKB=A8X139	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00106323\|UniProtKB=A0A2A6BWN5	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0031260\|UniProtKB=Q9VPQ7	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP008838\|UniProtKB=A0A1S4GZD8	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC009780\|UniProtKB=D6WPM6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_303875\|UniProtKB=E9GIM7	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG187510\|UniProtKB=T1FPA3	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g228311\|UniProtKB=A7RM71	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG58104\|UniProtKB=B3S2P9	Trichoplax adhaerens	LDO
YEAST\|SGD=S000001583\|UniProtKB=P34248	Saccharomyces cerevisiae	LDO
YARLI\|EnsemblGenome=YALI0_C04818g\|UniProtKB=Q6CD08	Yarrowia lipolytica	LDO
ASPFU\|EnsemblGenome=AFUA_6G02150\|UniProtKB=Q4WCR4	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU00568\|UniProtKB=Q7SF82	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_14173\|UniProtKB=A7F992	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_15633\|UniProtKB=Q0TXZ7	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC25B8.17\|UniProtKB=Q9UTA3	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_04583\|UniProtKB=B6K778	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNH00690\|UniProtKB=Q5KCE0	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_02729\|UniProtKB=A0A0D1E4M7	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_02590\|UniProtKB=E3JVS4	Puccinia graminis	LDO
ENTH1\|EnsemblGenome=CL6EHI_031250\|UniProtKB=C4M4K7	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0292836\|UniProtKB=Q54CN9	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_150570\|UniProtKB=F0ZGN7	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_29_0910\|UniProtKB=E9ADU8	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.3.4910\|UniProtKB=Q582P4	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_8429\|UniProtKB=A8B652	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_074490\|UniProtKB=A2E3W6	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_1457000\|UniProtKB=Q8IKQ9	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00024101001\|UniProtKB=A0E7V6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00029287001\|UniProtKB=A0BI84	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00017577001\|UniProtKB=A0DJL6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00001981001\|UniProtKB=A0D7C2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000125001\|UniProtKB=Q6BFK7	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00003474001\|UniProtKB=A0E5P5	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_15950\|UniProtKB=B8CDZ9	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3HE39_PHYRM\|UniProtKB=H3HE39	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_14g617300v5\|UniProtKB=A0A2K3CXQ3	Chlamydomonas reinhardtii	O
SELML\|EnsemblGenome=SELMODRAFT_161262\|UniProtKB=D8T5N7	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c3_4970\|UniProtKB=A0A2K1KTA6	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c4_28860\|UniProtKB=A0A2K1KQE2	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0108s0004\|UniProtKB=A0A2R6WCS1	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0110s0052\|UniProtKB=A0A2R6WCI4	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_001280040\|UniProtKB=A0A1Y1HW60	Klebsormidium nitens	O
CHLRE\|EnsemblGenome=CHLRE_07g332550v5\|UniProtKB=A8IGT6	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00019p00244000\|UniProtKB=W1PHE6	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_37G00670\|UniProtKB=A0A0K9P7I9	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma01_g17950\|UniProtKB=A0A804HVF2	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma05_g08430\|UniProtKB=A0A804J2A0	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_017696mg\|UniProtKB=K3YTV0	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G103900\|UniProtKB=A0A1B6QIA0	Sorghum bicolor	O
SORBI\|EnsemblGenome=SORBI_3003G207500\|UniProtKB=A0A1W0VYD0	Sorghum bicolor	O
SORBI\|EnsemblGenome=SORBI_3004G013100\|UniProtKB=C5XSC1	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb230050\|UniProtKB=A0A1D6GYP1	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb209380\|UniProtKB=B4FP26	Zea mays	LDO
ORYSJ\|Gene_OrderedLocusName=LOC_Os05g36070\|UniProtKB=B9FJ61	Oryza sativa	O
ORYSJ\|EnsemblGenome=Os02g0117400\|UniProtKB=Q6ZGL9	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g01610v3\|UniProtKB=I1HWE2	Brachypodium distachyon	O
BRADI\|EnsemblGenome=BRADI_1g78070v3\|UniProtKB=I1HAR1	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0546530\|UniProtKB=M0Y541	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS6B02G064600\|UniProtKB=A0A3B6PFU8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCSU02G107100\|UniProtKB=A0A3B6U655	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6B02G064500\|UniProtKB=A0A3B6PHL3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G048100\|UniProtKB=A0A3B6NJQ9	Triticum aestivum	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0320840\|UniProtKB=A0A8I6XU83	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS3B02G545500\|UniProtKB=W5CYY7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3D02G492200\|UniProtKB=A0A3B6H3C3	Triticum aestivum	LDO
NELNU\|Gene=LOC104611314\|UniProtKB=A0A1U8BHZ6	Nelumbo nucifera	LDO
NELNU\|Gene=LOC104606046\|UniProtKB=A0A1U8Q846	Nelumbo nucifera	O
SPIOL\|Gene=LOC110783305\|UniProtKB=A0A9R0I6C5	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr16g0748281\|UniProtKB=A0A251SNB7	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C900476020\|UniProtKB=A0A9R1WWW8	Lactuca sativa	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr08g0327821\|UniProtKB=A0A251U3C4	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C800399480\|UniProtKB=A0A9R1WZA4	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a009513mg\|UniProtKB=A0A022S2R7	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a009419mg\|UniProtKB=A0A022R6U1	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_01808\|UniProtKB=A0A1U8HBE2	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400022714\|UniProtKB=M1C2R5	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc01g008820.3\|UniProtKB=A0A3Q7ESI2	Solanum lycopersicum	O
TOBAC\|Gene=LOC107807256\|UniProtKB=A0A1S4BDW8	Nicotiana tabacum	O
TOBAC\|Gene=LOC107767668\|UniProtKB=A0A1S3XRB8	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_27978\|UniProtKB=A0A1U8ENT5	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400009454\|UniProtKB=M1AK48	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc11g064790.2\|UniProtKB=A0A3Q7JNB1	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107791309\|UniProtKB=A0A1S3ZWR1	Nicotiana tabacum	O
TOBAC\|Gene=LOC107780850\|UniProtKB=A0A1S3YXL7	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi06g01242\|UniProtKB=D7T153	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_J00700\|UniProtKB=A0A059ABS8	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_A02P33230.1\|UniProtKB=A0A078F8B0	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C02P51130.1\|UniProtKB=A0A078JAB0	Brassica napus	O
BRACM\|EnsemblGenome=Bra026567\|UniProtKB=A0A3P6AIV5	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_A09P24090.1\|UniProtKB=A0A078J783	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C09P30980.1\|UniProtKB=A0A078FWA1	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A06P43280.1\|UniProtKB=A0A078I6Y8	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra024788\|UniProtKB=A0A397ZD65	Brassica campestris	LDO
ARATH\|TAIR=locus=2056936\|UniProtKB=O81062	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107954323\|UniProtKB=A0A1U8P542	Gossypium hirsutum	O
GOSHI\|Gene=LOC107939471\|UniProtKB=A0A1U8MNA1	Gossypium hirsutum	O
GOSHI\|Gene=LOC107953180\|UniProtKB=A0A1U8NY73	Gossypium hirsutum	O
GOSHI\|Gene=LOC107944956\|UniProtKB=A0A1U8N5M6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107959288\|UniProtKB=A0A1U8PKR3	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_040944\|UniProtKB=A0A061GUR2	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g019365mg\|UniProtKB=A0A067EIE2	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_009G071600v3\|UniProtKB=B9HNF4	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_001G276700v3\|UniProtKB=B9GG92	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_01G179800\|UniProtKB=A0A2C9WLM2	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_02G140400\|UniProtKB=A0A2C9WG26	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0833830\|UniProtKB=B9SM25	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_04G080200\|UniProtKB=I1JUR9	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_14G142100\|UniProtKB=C6T9X4	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_06G081900\|UniProtKB=I1K992	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g008280\|UniProtKB=G7I4B6	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_3g109932\|UniProtKB=A0A072V2B2	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr08_03230\|UniProtKB=A0A2I4FPX2	Juglans regia	O
JUGRE\|EnsemblGenome=Jr11_27280\|UniProtKB=A0A2I4GNU0	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G889120\|UniProtKB=A0A0A0LGU3	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G452500\|UniProtKB=M5XCL4	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_153968\|UniProtKB=D8S0R8	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c3_24000\|UniProtKB=A0A2K1KVR2	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0057s0081\|UniProtKB=A0A2R6WUF2	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001640100\|UniProtKB=A0A0U9HT31	Klebsormidium nitens	LDO
METAC\|EnsemblGenome=MA_4000\|UniProtKB=Q8TIY9	Methanosarcina acetivorans	O