PANTHER Gene Information

Gene Symbol(s):

IscW_ISCW010491

Organism:

Ixodes scapularis

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Tree

Gene Name:

Ubiquitin carboxyl-terminal hydrolase

Gene ID:

ISCW010491

Protein ID:

B7Q817

Persistent Id:

PTN001050017

Alternate Ids:

EEC14989(EMBL-CDS)	ABJB011000227(EMBL)
ISCW010491(Ensembl)	241729585(GI)
B7Q817_IXOSC(UniProtKB-ID)	XM_002404563(refSeq)
ISCW010491-RA(Ensembl_TRS)	ISCW010491-PA(Ensembl_PRO)
B7Q817(Synonym)
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PANTHER Classification

PANTHER Family:	NF-E2 INDUCIBLE PROTEIN (PTHR18063)
PANTHER Subfamily:	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE (PTHR18063:SF6)
PANTHER GO-slim Molecular Function:	carboxypeptidase activity cysteine-type peptidase activity deubiquitinase activity
PANTHER GO-slim Biological Process:	protein K48-linked deubiquitination
PANTHER GO-slim Cellular Component:	cell periphery cytosol
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	cysteine-type deubiquitinase activity, histone deubiquitinase activity, cysteine-type carboxypeptidase activity, cysteine-type peptidase activity, K48-linked deubiquitinase activity, K48-linked polyubiquitin modification-dependent protein binding
GO BP Complete:	chromatin remodeling, proteolysis
GO CC Complete:	-

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=25648\|UniProtKB=Q8N5J2	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000001270.6\|UniProtKB=A0A2J8JJA5	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000001534.3\|UniProtKB=A0A2I2ZBS4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000010067.4\|UniProtKB=A0A5F8ADN5	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1922257\|UniProtKB=Q76LS9	Mus musculus	LDO
RAT\|RGD=1559660\|UniProtKB=Q5BJQ2	Rattus norvegicus	LDO
BOVIN\|Gene=MINDY1\|UniProtKB=Q2KJ22	Bos taurus	LDO
BOVIN\|Ensembl=ENSBTAG00000015329.4\|UniProtKB=F1N422	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000006642.5\|UniProtKB=F1SS98	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000009096.3\|UniProtKB=F6Y5P3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000009660.6\|UniProtKB=M3WBV2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845020685.1\|UniProtKB=A0A8I3P9M7	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000018827.3\|UniProtKB=F7GKG5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000045875.1\|UniProtKB=A0A6I8N8F3	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010028585.1\|UniProtKB=A0A8V1A9M4	Gallus gallus	LDO
XENLA\|Gene=mindy1.S\|UniProtKB=A0A1L8F4Q2	Xenopus laevis	O
XENLA\|Gene=mindy1.L\|UniProtKB=A0A1L8FCP1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5884908\|UniProtKB=A0A6I8PUD6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000001245.2\|UniProtKB=A0A3B3HFJ6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-070717-3\|UniProtKB=A0A8M2B678	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-070717-2\|UniProtKB=A3KQS4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000008413.1\|UniProtKB=W5MPB9	lepisosteus oculatus	LDO
HUMAN\|HGNC=26954\|UniProtKB=Q8NBR6	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000044903.1\|UniProtKB=A0A2I3TI05	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000000256.3\|UniProtKB=G3QDD9	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000018109.4\|UniProtKB=A0A1D5QHZ4	Macaca mulatta	O
MOUSE\|MGI=MGI=2443086\|UniProtKB=Q6PDI6	Mus musculus	O
RAT\|RGD=1311456\|UniProtKB=D3ZWA1	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000012391\|UniProtKB=Q2KI23	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000024131.4\|UniProtKB=I3LA32	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000019456.3\|UniProtKB=A0A9L0RN94	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000025467.4\|UniProtKB=A0A5F5XPG8	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845015725.1\|UniProtKB=A0A8I3NUV4	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000008761.3\|UniProtKB=F6RGW0	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000038536.1\|UniProtKB=A0A6I8PB92	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010022976.1\|UniProtKB=F6VFQ9	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000015045.4\|UniProtKB=H9GLX4	Anolis carolinensis	O
XENLA\|Gene=mindy2.S\|UniProtKB=A0A1L8GT27	Xenopus laevis	O
XENLA\|Gene=mindy2.L\|UniProtKB=A0A1L8H0J6	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-990463\|UniProtKB=A0A8J0QU02	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000008169.2\|UniProtKB=A0A3B3H4X8	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030616-328\|UniProtKB=F1RBY0	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000013626.1\|UniProtKB=W5N840	lepisosteus oculatus	O
BRAFL\|Gene=LOC118412240\|UniProtKB=A0A9J7KUS9	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC586249\|UniProtKB=A0A7M7RG55	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC115918873\|UniProtKB=A0A7M7PC10	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00021926\|UniProtKB=Q9N370	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG13966\|UniProtKB=A8XIX8	Caenorhabditis briggsae	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_330084\|UniProtKB=E9HIH8	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_48508\|UniProtKB=E9GBM7	Daphnia pulex	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_323426\|UniProtKB=E9GYU5	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_335520\|UniProtKB=E9HXY6	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_270490\|UniProtKB=E9I0T4	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG73057\|UniProtKB=T1G193	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g130466\|UniProtKB=A7SSZ3	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG18339\|UniProtKB=B3RJP5	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_34177\|UniProtKB=A9VA14	Monosiga brevicollis	LDO
YEAST\|SGD=S000006112\|UniProtKB=Q08930	Saccharomyces cerevisiae	O
YEAST\|SGD=S000003050\|UniProtKB=P53155	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFL071C\|UniProtKB=Q754Y2	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000175986\|UniProtKB=A0A1D8PIB7	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E13970g\|UniProtKB=Q6C5Y9	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_08067\|UniProtKB=Q5AUG3	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_5G01840\|UniProtKB=Q4WE57	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU03336\|UniProtKB=Q1K531	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_01834\|UniProtKB=A7E954	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_16454\|UniProtKB=Q0TVL0	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC12G12.11c\|UniProtKB=Q09874	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_01481\|UniProtKB=B6JY23	Schizosaccharomyces japonicus	LDO
USTMA\|EnsemblGenome=UMAG_06258\|UniProtKB=A0A0D1BUU2	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_16863\|UniProtKB=E3L3J3	Puccinia graminis	LDO
PUCGT\|EnsemblGenome=PGTG_05755\|UniProtKB=E3K4K7	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_89658\|UniProtKB=F4P6C8	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0269770\|UniProtKB=Q55D67	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_82343\|UniProtKB=F0ZW90	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0281445\|UniProtKB=Q54TY0	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_57374\|UniProtKB=F0ZVP4	Dictyostelium purpureum	LDO
TRYB2\|Gene_ORFName=Tb927.6.4380\|UniProtKB=Q587A4	Trypanosoma brucei	LDO
PLAF7\|Gene_ORFName=PF3D7_1319100\|UniProtKB=A0A5K1K970	Plasmodium falciparum	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_885\|UniProtKB=B8BSQ5	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GZU9_PHYRM\|UniProtKB=H3GZU9	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_06g304850v5\|UniProtKB=A0A2K3DR81	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00001p00199010\|UniProtKB=W1NLG1	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_76G00220\|UniProtKB=A0A0K9NNX7	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma09_g21240\|UniProtKB=A0A804KM16	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_021037mg\|UniProtKB=K3Z3C0	Setaria italica	O
SETIT\|EnsemblGenome=SETIT_032976mg\|UniProtKB=K4A279	Setaria italica	O
MAIZE\|EnsemblGenome=Zm00001eb033330\|UniProtKB=A0A804LSI8	Zea mays	O
SETIT\|EnsemblGenome=SETIT_000408mg\|UniProtKB=K3XEU1	Setaria italica	O
SETIT\|EnsemblGenome=SETIT_007102mg\|UniProtKB=K3XYU4	Setaria italica	O
SETIT\|EnsemblGenome=SETIT_026091mg\|UniProtKB=K3ZHN9	Setaria italica	O
SETIT\|EnsemblGenome=SETIT_011174mg\|UniProtKB=K3YAD2	Setaria italica	O
SETIT\|EnsemblGenome=SETIT_005962mg\|UniProtKB=K3XVK4	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3010G261600\|UniProtKB=C5Z9F6	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb357270\|UniProtKB=K7V327	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb033290\|UniProtKB=A0A804LSI5	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb272510\|UniProtKB=A0A1D6LN44	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb227790\|UniProtKB=A0A1D6GW67	Zea mays	LDO
ORYSJ\|Gene_OrderedLocusName=Os06g0718800\|UniProtKB=A0A0N7KMR2	Oryza sativa	O
ORYSJ\|EnsemblGenome=Os06g0721600\|UniProtKB=A0A0P0X107	Oryza sativa	O
ORYSJ\|EnsemblGenome=Os06g0723400\|UniProtKB=A0A0P0X120	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g10787v3\|UniProtKB=A0A2K2CWG7	Brachypodium distachyon	O
ORYSJ\|Gene_OrderedLocusName=Os08g0527500\|UniProtKB=A0A0P0XI63	Oryza sativa	O
ORYSJ\|EnsemblGenome=Os06g0712400\|UniProtKB=Q5Z800	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_2g53422v3\|UniProtKB=A0A0Q3IX99	Brachypodium distachyon	O
BRADI\|EnsemblGenome=BRADI_1g34980v3\|UniProtKB=I1GWZ1	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.7HG0725220\|UniProtKB=A0A8I6YQM9	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCSU02G072900\|UniProtKB=A0A3B6U558	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7A02G406200\|UniProtKB=A0A3B6RNJ5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7D02G399900\|UniProtKB=A0A3B6TNL7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5D02G032000\|UniProtKB=A0A3B6MIV0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7B02G306200\|UniProtKB=A0A3B6SQH8	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_018000\|UniProtKB=A0A1U8B991	Nelumbo nucifera	O
NELNU\|Gene=LOC104596216\|UniProtKB=A0A1U7ZTY7	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110784349\|UniProtKB=A0A9R0I7Y5	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HannXRQ_Chr11g0336621\|UniProtKB=A0A251TA11	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr13g0602611\|UniProtKB=A0A251VGD7	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr13g0602591\|UniProtKB=A0A251VH31	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr03g0127021\|UniProtKB=A0A9K3JII8	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr07g0281691\|UniProtKB=A0A9K3NES5	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C600303240\|UniProtKB=A0A9R1X5P6	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a021657mg\|UniProtKB=A0A022RFP3	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a003325mg\|UniProtKB=A0A022RJF6	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a022265mg\|UniProtKB=A0A022RB56	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_00401\|UniProtKB=A0A2G3AE50	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400022735\|UniProtKB=M1C2T5	Solanum tuberosum	LDO
TOBAC\|Gene=LOC107780665\|UniProtKB=A0A1S3YX08	Nicotiana tabacum	O
TOBAC\|Gene=LOC107824775\|UniProtKB=A0A1S4D172	Nicotiana tabacum	LDO
VITVI\|Gene_OrderedLocusName=VIT_02s0025g04640\|UniProtKB=F6HUI9	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_D01937\|UniProtKB=A0A059CGW0	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_D01936\|UniProtKB=A0A059CHB0	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_D01938\|UniProtKB=A0A059CI77	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00048698001\|UniProtKB=A0A078FBV6	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00072691001\|UniProtKB=A0A078HUA1	Brassica napus	O
BRACM\|EnsemblGenome=Bra013664\|UniProtKB=M4DB04	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_C09P34580.1\|UniProtKB=A0A078FFW1	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra029419\|UniProtKB=M4EKV2	Brassica campestris	LDO
ARATH\|TAIR=locus=2127223\|UniProtKB=F4JMQ2	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2137050\|UniProtKB=Q8LE63	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107930061\|UniProtKB=A0A1U8LV50	Gossypium hirsutum	O
GOSHI\|Gene=LOC107896488\|UniProtKB=A0A1U8IGA5	Gossypium hirsutum	O
GOSHI\|Gene=LOC107923040\|UniProtKB=A0A1U8L235	Gossypium hirsutum	O
GOSHI\|Gene=LOC107890677\|UniProtKB=A0A1U8I3A2	Gossypium hirsutum	O
GOSHI\|Gene=LOC107904497\|UniProtKB=A0A1U8JCH6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107926977\|UniProtKB=A0A1U8LFN7	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_016149\|UniProtKB=A0A061G3Z3	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g036470mg\|UniProtKB=A0A067F8A8	Citrus sinensis	LDO
POPTR\|Gene_ORFName=POPTR_003G119800\|UniProtKB=A0A3N7FN89	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_001G112300v3\|UniProtKB=A0A2K2BVX1	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_01G069600\|UniProtKB=A0A2C9WIK5	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_02G030300\|UniProtKB=A0A2C9WAF7	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1682960\|UniProtKB=B9RBZ9	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_11G027200\|UniProtKB=I1LGI8	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_04G257400\|UniProtKB=A0A0R0KCT6	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_11G000100\|UniProtKB=A0A0R0HA67	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_03G264900\|UniProtKB=A0A0R0KQB7	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_01G214700\|UniProtKB=I1JA20	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_5g011090\|UniProtKB=G7KES5	Medicago truncatula	LDO
JUGRE\|Gene=LOC108990681\|UniProtKB=A0A6P9ELC7	Juglans regia	O
JUGRE\|EnsemblGenome=Jr09_11820\|UniProtKB=A0A2I4EM70	Juglans regia	LDO
JUGRE\|Gene=LOC108990688\|UniProtKB=A0A2I4ELJ3	Juglans regia	O
JUGRE\|Gene=LOC108990852\|UniProtKB=A0A6P9F5C6	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_5G156160\|UniProtKB=A0A0A0KR01	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_5G088000\|UniProtKB=M5WT77	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_437710\|UniProtKB=D8QP19	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c12_2860\|UniProtKB=A9SWI0	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c17_3230\|UniProtKB=A0A2K1J2L0	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0108s0010\|UniProtKB=A0A2R6WCS7	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_004060050\|UniProtKB=A0A1Y1IGI4	Klebsormidium nitens	LDO