PANTHER Gene Information

Gene Symbol(s):

IscW_ISCW017525

Organism:

Ixodes scapularis

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Tree

Gene Name:

Calcium-dependent cysteine protease, putative

Gene ID:

ISCW017525

Protein ID:

B7PB22

Persistent Id:

PTN000809596

Alternate Ids:

XM_002407589(refSeq)	215494153(GI)
EEC03794(EMBL-CDS)	ISCW017525(Ensembl)
B7PB22(Synonym)	DS674345(EMBL)
ISCW017525-PA(Ensembl_PRO)	ISCW017525-RA(Ensembl_TRS)
B7PB22_IXOSC(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	CALPAIN (PTHR10183)
PANTHER Subfamily:	CALPAIN-15 (PTHR10183:SF382)
PANTHER GO-slim Molecular Function:	cysteine-type endopeptidase activity
PANTHER GO-slim Biological Process:	proteolysis
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	cysteine protease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	metal ion binding, cysteine-type peptidase activity, calcium-dependent cysteine-type endopeptidase activity
GO BP Complete:	proteolysis
GO CC Complete:	cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11182\|UniProtKB=O75808	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000045173.1\|UniProtKB=A0A2I3S5I6	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000007870.3\|UniProtKB=G3RMF5	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000000615.4\|UniProtKB=F6Y261	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1355075\|UniProtKB=Q9JLG8	Mus musculus	LDO
RAT\|RGD=1306514\|UniProtKB=A0A0G2KAS0	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000016592.6\|UniProtKB=E1B6Y0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000007993.5\|UniProtKB=F1RGT7	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000011148.3\|UniProtKB=A0A9L0RDC6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000024851.4\|UniProtKB=A0A5F5XC12	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845028201.1\|UniProtKB=A0A8I3PVS1	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000016682.4\|UniProtKB=A0A5F8GQ72	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000042617.1\|UniProtKB=A0A6I8P004	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010018046.1\|UniProtKB=A0A8V0Z4B9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000003352.4\|UniProtKB=H9G7D7	Anolis carolinensis	LDO
XENLA\|Gene=capn15.S\|UniProtKB=A0A8J0TTV9	Xenopus laevis	O
XENLA\|Gene=capn15.L\|UniProtKB=A0A8J1LR99	Xenopus laevis	LDO
XENTR\|Gene=capn15\|UniProtKB=A0A8J1IRW8	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000000290.2\|UniProtKB=A0A3B3I454	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000007128.2\|UniProtKB=A0A3B3HRH6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-140106-70\|UniProtKB=A0A8M2BLF5	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000009003.1\|UniProtKB=W5MRF9	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004834.3\|UniProtKB=F6TZD9	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118418984\|UniProtKB=A0A9J7LDY2	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC579407\|UniProtKB=A0A7M7SWK8	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00021041\|UniProtKB=O44903	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00009695\|UniProtKB=O02260	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00011705\|UniProtKB=G5EEZ6	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG04776\|UniProtKB=A8WYG0	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG00485\|UniProtKB=A8WMS0	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00038627\|UniProtKB=A8XVI8	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00280481\|UniProtKB=A0A2A6C011	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0003464\|UniProtKB=P27398	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP000829\|UniProtKB=A0A1S4GAR2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC031093\|UniProtKB=A0A139WJ06	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_303248\|UniProtKB=E9FU36	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG192664\|UniProtKB=T1FU62	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g169580\|UniProtKB=A7SE78	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG25226\|UniProtKB=B3RX80	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_26418\|UniProtKB=A9V2B3	Monosiga brevicollis	LDO
EMENI\|EnsemblGenome=ANIA_10513\|UniProtKB=C8V4M8	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_6G07970\|UniProtKB=Q4WN14	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU00251\|UniProtKB=Q7RZW0	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_08871\|UniProtKB=A7EU64	Sclerotinia sclerotiorum	O
NEUCR\|EnsemblGenome=NCU03355\|UniProtKB=Q1K520	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_07272\|UniProtKB=A7EPM3	Sclerotinia sclerotiorum	O
NEUCR\|EnsemblGenome=NCU01151\|UniProtKB=Q7S7N5	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_00862\|UniProtKB=A7E6D7	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_12303\|UniProtKB=Q0U7G1	Phaeosphaeria nodorum	O
BATDJ\|Gene_ORFName=BATDEDRAFT_85291\|UniProtKB=F4NTM9	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_045290\|UniProtKB=C4LTE2	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0269200\|UniProtKB=Q8MUF9	Dictyostelium discoideum	O
LEIMA\|EnsemblGenome=LMJF_27_0490\|UniProtKB=E9AD26	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_27_0500\|UniProtKB=E9AD27	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_27_0510\|UniProtKB=E9AD28	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.47.0036\|UniProtKB=Q387E0	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb11.57.0008\|UniProtKB=Q387E1	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb11.v4.0001\|UniProtKB=Q387D8	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb11.47.0035\|UniProtKB=Q387D9	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_18_1060\|UniProtKB=Q4QDT6	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.6.3310\|UniProtKB=Q584X4	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_21_0120\|UniProtKB=Q4QCK4	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.70.5950\|UniProtKB=Q38C53	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_31_0460\|UniProtKB=Q4Q6L7	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_36_0780\|UniProtKB=Q4Q1Z8	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_30_2040\|UniProtKB=Q4Q790	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_25_1480\|UniProtKB=Q4Q9U3	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.389.0470\|UniProtKB=Q388U3	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb11.01.1140\|UniProtKB=Q383Z2	Trypanosoma brucei	O
TRIV3\|Gene_ORFName=TVAG_164300\|UniProtKB=A2E1X1	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_161170\|UniProtKB=A2E4X2	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_023460\|UniProtKB=A2FEL7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_299900\|UniProtKB=A2FAE4	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_183710\|UniProtKB=A2D9A8	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_140890\|UniProtKB=A2FER3	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_256510\|UniProtKB=A2FHB3	Trichomonas vaginalis	O
PARTE\|EnsemblGenome=GSPATT00007090001\|UniProtKB=A0CDL2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00037153001\|UniProtKB=A0CC52	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00029194001\|UniProtKB=A0BHZ1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00005173001\|UniProtKB=A0BPF7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00015324001\|UniProtKB=A0DBL1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00029179001\|UniProtKB=A0BHX6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00030291001\|UniProtKB=A0BM88	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00008699001\|UniProtKB=A0CN91	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00037860001\|UniProtKB=A0CF54	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00017996001\|UniProtKB=A0DKW2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00033867001\|UniProtKB=A0C0S4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00029121001\|UniProtKB=A0BHR8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00022340001\|UniProtKB=A0E1K3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00037859001\|UniProtKB=A0CF53	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00007371001\|UniProtKB=A0CGL4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016301001\|UniProtKB=A0DEK8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00030963001\|UniProtKB=A0BQB7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000882001\|UniProtKB=A0CK52	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00030741001\|UniProtKB=A0BNI6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016575001\|UniProtKB=A0DFE5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00020108001\|UniProtKB=A0DTQ9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026279001\|UniProtKB=A0EF65	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00022226001\|UniProtKB=A0E190	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00032570001\|UniProtKB=A0BW01	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00029862001\|UniProtKB=A0BL14	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00030977001\|UniProtKB=A0BQD1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00018249001\|UniProtKB=A0DLL4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00029264001\|UniProtKB=A0BI61	Paramecium tetraurelia	O
PHYRM\|Gene=H3GEW3_PHYRM\|UniProtKB=H3GEW3	Phytophthora ramorum	O
PHYRM\|Gene=H3GS02_PHYRM\|UniProtKB=H3GS02	Phytophthora ramorum	O
PHYRM\|Gene=H3HC70_PHYRM\|UniProtKB=H3HC70	Phytophthora ramorum	O
PHYRM\|Gene=H3GMV4_PHYRM\|UniProtKB=H3GMV4	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_05g241202v5\|UniProtKB=A0A2K3DT87	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_10g448850v5\|UniProtKB=A0A2K3DB06	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_17g728300v5\|UniProtKB=A0A2K3CQR8	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_02g112300v5\|UniProtKB=A0A2K3E334	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00047p00125370\|UniProtKB=U5DBI3	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_96G00380\|UniProtKB=A0A0K9NHX8	Zostera marina	O
MUSAM\|EnsemblGenome=Ma06_g10860\|UniProtKB=A0A804JEX5	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_033839mg\|UniProtKB=K4A4N5	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3001G400500\|UniProtKB=C5WML7	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb014030\|UniProtKB=A0A1D6JZV9	Zea mays	O
MAIZE\|Gene=DEK1\|UniProtKB=Q8RVL1	Zea mays	O
ORYSJ\|Gene_OrderedLocusName=LOC_Os02g47970\|UniProtKB=Q6ZFZ4	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g53020v3\|UniProtKB=I1ID37	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0608170\|UniProtKB=B6C9J6	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS6B02G302900\|UniProtKB=A0A3B6PNN0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G255800\|UniProtKB=A0A3B6QGU2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G275500\|UniProtKB=A0A3B6NTU0	Triticum aestivum	O
NELNU\|Gene_ORFName=HUJ06_000316\|UniProtKB=A0A1U8A845	Nelumbo nucifera	O
SPIOL\|Gene=LOC110790437\|UniProtKB=A0A9R0IKG8	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr02g0083571\|UniProtKB=A0A251VK25	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr13g0590641\|UniProtKB=A0A251STG8	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C600319170\|UniProtKB=A0A9R1X696	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a023650mg\|UniProtKB=A0A022QEI4	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a000044mg\|UniProtKB=A0A022RK49	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_34677\|UniProtKB=A0A2G2XVD7	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_35194\|UniProtKB=A0A2G2XTY6	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_34711\|UniProtKB=A0A2G2XV90	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_34498\|UniProtKB=A0A2G2XVV7	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_35048\|UniProtKB=A0A2G2XUG0	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400004280\|UniProtKB=M0ZYS9	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc12g100353.1\|UniProtKB=A0A3Q7JFZ8	Solanum lycopersicum	O
TOBAC\|Gene=LOC107784464\|UniProtKB=A0A1S3Z9M7	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi06g00045\|UniProtKB=D7SLL2	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_J01766\|UniProtKB=A0A059AEU0	Eucalyptus grandis	O
BRANA\|Gene_ORFName=GSBRNA2T00095790001\|UniProtKB=A0A078IGL8	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00053667001\|UniProtKB=A0A078H6M4	Brassica napus	O
BRACM\|EnsemblGenome=Bra037995\|UniProtKB=M4FA81	Brassica campestris	O
ARATH\|TAIR=locus=2035676\|UniProtKB=Q8RVL2	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107963811\|UniProtKB=A0A1U8PZJ3	Gossypium hirsutum	O
GOSHI\|Gene=LOC107927100\|UniProtKB=A0A1U8LG75	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_038725\|UniProtKB=A0A061GQB8	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g000112mg\|UniProtKB=A0A067EH92	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_003G221100v3\|UniProtKB=A0A2K2BAU9	Populus trichocarpa	O
POPTR\|Gene_ORFName=POPTR_001G003900\|UniProtKB=A0A3N7FVJ3	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_03G087600\|UniProtKB=A0A2C9W5T3	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0343760\|UniProtKB=B9SBQ0	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_05G167200\|UniProtKB=I1K484	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_08G125500\|UniProtKB=I1KSP1	Glycine max	O
MEDTR\|EnsemblGenome=MTR_8g088520\|UniProtKB=G7L8S3	Medicago truncatula	O
JUGRE\|Gene=LOC109002175\|UniProtKB=A0A6P9EFF6	Juglans regia	O
JUGRE\|EnsemblGenome=Jr14_22020\|UniProtKB=A0A2I4FZU5	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_1G599520\|UniProtKB=A0A0A0LX51	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_6G003300\|UniProtKB=M5W795	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_236021\|UniProtKB=D8T469	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_235391\|UniProtKB=D8SWW6	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c17_17550\|UniProtKB=A0A2K1J4D2	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0026s0110\|UniProtKB=A0A2R6XAY6	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0026s0090\|UniProtKB=A0A2R6XAU3	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_000500480\|UniProtKB=A0A1Y1HNS0	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_003860020\|UniProtKB=A0A1Y1IGP1	Klebsormidium nitens	O