PANTHER Gene Information

Gene Symbol(s):

IscW_ISCW017984

Organism:

Ixodes scapularis

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Gene Name:

RNase H type-1 domain-containing protein

Gene ID:

ISCW017984

Protein ID:

B7PIC8

Persistent Id:

PTN008502811

Alternate Ids:

XM_002404765(refSeq)	215496710(GI)
EEC06350(EMBL-CDS)	ISCW017984(Ensembl)
B7PIC8(Synonym)	ABJB010325482(EMBL)
ISCW017984-PA(Ensembl_PRO)	ISCW017984-RA(Ensembl_TRS)
B7PIC8_IXOSC(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	RIBONUCLEASE H1 (PTHR10642)
PANTHER Subfamily:	RIBONUCLEASE H1 (PTHR10642:SF26)
PANTHER GO-slim Molecular Function:	RNA endonuclease activity
PANTHER GO-slim Biological Process:	DNA replication RNA catabolic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	endoribonuclease

Pathway Categories:

DNA replication

RNase H

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	nucleic acid binding, RNA-DNA hybrid ribonuclease activity
GO BP Complete:	DNA replication, removal of RNA primer
GO CC Complete:	-

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=18466\|UniProtKB=O60930	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000043403.1\|UniProtKB=A0A2I3S7A3	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000011614.4\|UniProtKB=H2QHD3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000034822.2\|UniProtKB=G3SKF3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000014475.4\|UniProtKB=H9FSB3	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1335073\|UniProtKB=O70338	Mus musculus	LDO
RAT\|RGD=1309012\|UniProtKB=Q5BK46	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000016235.5\|UniProtKB=A0A3Q1M0N2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000025305.4\|UniProtKB=I3LTQ9	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000020695.4\|UniProtKB=A0A5F5PXA2	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000025832.4\|UniProtKB=M3WVC8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845021474.1\|UniProtKB=A0A8I3PFR3	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000028814.2\|UniProtKB=K7E161	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000014491.2\|UniProtKB=F7FKT3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000050401.1\|UniProtKB=A0A6I8NDZ4	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010002291.1\|UniProtKB=A0A8V0XFB3	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000016857.4\|UniProtKB=H9GNP0	Anolis carolinensis	LDO
XENLA\|Gene=mgc146443.L\|UniProtKB=Q58E11	Xenopus laevis	O
XENLA\|Gene=MGC146443.S\|UniProtKB=A0A8J0VDP2	Xenopus laevis	O
XENTR\|Gene=LOC100493932\|UniProtKB=A0A8J0QQN8	Xenopus tropicalis	O
XENLA\|Gene=rnaseh1.L\|UniProtKB=A0A8J0VEB1	Xenopus laevis	O
XENLA\|Gene=rnaseh1.S\|UniProtKB=A0A8J1KUK9	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1011883\|UniProtKB=F7BUX9	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000023471.1\|UniProtKB=A0A3B3HTC1	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000018127.2\|UniProtKB=H2MV74	Oryzias latipes	LDO
DANRE\|Gene=rnaseh1\|UniProtKB=A0A8M1N0V4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000017212.1\|UniProtKB=W5NKX1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000014054.2\|UniProtKB=F6QPH0	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118410125\|UniProtKB=A0A9J7KP15	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC584833\|UniProtKB=A0A7M7NNK8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115918531\|UniProtKB=A0A7M7NK35	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00007303\|UniProtKB=Q9XVE6	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG_20847\|UniProtKB=A8XYS2	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00011664\|UniProtKB=Q7YTF8	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG03113\|UniProtKB=A8WSR7	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00004382\|UniProtKB=Q86MG7	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00031618\|UniProtKB=A8XAI2	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00276063\|UniProtKB=A0A2A6CSB5	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00110519\|UniProtKB=A0A8R1YF36	Pristionchus pacificus	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_273096\|UniProtKB=E9I3D6	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_250765\|UniProtKB=E9GZ88	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG164127\|UniProtKB=T1EUZ1	helobdella robusta	LDO
HELRO\|EnsemblGenome=HelroG156844\|UniProtKB=T1EM18	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g243990\|UniProtKB=A7SAK2	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG28584\|UniProtKB=B3S3Z5	Trichoplax adhaerens	LDO
CANAL\|CGD=CAL0000184579\|UniProtKB=A0A1D8PQ03	Candida albicans	O
CANAL\|CGD=CAL0000191701\|UniProtKB=Q5ABY8	Candida albicans	O
CANAL\|CGD=CAL0000187941\|UniProtKB=A0A1D8PQ43	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_A16082g\|UniProtKB=Q6CGU7	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_A12705g\|UniProtKB=Q6CH42	Yarrowia lipolytica	O
YEAST\|SGD=S000004847\|UniProtKB=Q04740	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_ABL017C\|UniProtKB=Q75DN4	Eremothecium gossypii	LDO
YARLI\|EnsemblGenome=YALI0_A10989g\|UniProtKB=Q6CH96	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_F26543g\|UniProtKB=Q6C0A0	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_A04521g\|UniProtKB=Q6CHV6	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_F25729g\|UniProtKB=Q6C0D2	Yarrowia lipolytica	LDO
YARLI\|EnsemblGenome=YALI0_F25751g\|UniProtKB=Q6C0D1	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_A06523g\|UniProtKB=Q6CHQ1	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_A12683g\|UniProtKB=Q6CH43	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_E10725g\|UniProtKB=Q6C6C0	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_A09878g\|UniProtKB=Q6CHD9	Yarrowia lipolytica	LDO
YARLI\|EnsemblGenome=YALI0_B21494g\|UniProtKB=Q6CDS8	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_A15059g\|UniProtKB=Q6CGX9	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_A16148g\|UniProtKB=Q6CGU6	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_10625\|UniProtKB=C8V7Z8	Emericella nidulans	O
PHANO\|EnsemblGenome=SNOG_16556\|UniProtKB=Q0TVA8	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_03980\|UniProtKB=Q5B650	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_07977\|UniProtKB=Q5AUQ3	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_07094\|UniProtKB=Q5AX86	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_05188\|UniProtKB=C8VF62	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G10020\|UniProtKB=Q4WTA2	Neosartorya fumigata	O
ASPFU\|EnsemblGenome=AFUA_1G07180\|UniProtKB=Q4WJ55	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU08107\|UniProtKB=Q7SCX3	Neurospora crassa	O
NEUCR\|EnsemblGenome=NCU05108\|UniProtKB=Q7RYF8	Neurospora crassa	O
NEUCR\|EnsemblGenome=NCU05750\|UniProtKB=Q7S4S2	Neurospora crassa	LDO
PHANO\|EnsemblGenome=SNOG_15995\|UniProtKB=Q0TWR7	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_13731\|UniProtKB=Q0U3D3	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_05579\|UniProtKB=Q0URN5	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC336.06c\|UniProtKB=Q9UST8	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_06022\|UniProtKB=T0S170	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNJ01860\|UniProtKB=Q5KAF8	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNA03470\|UniProtKB=Q5KPB0	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_10765\|UniProtKB=A0A0D1E307	Ustilago maydis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_28244\|UniProtKB=F4PDE6	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_042240\|UniProtKB=C4M4H8	Entamoeba histolytica	LDO
LEIMA\|EnsemblGenome=LMJF_06_0290\|UniProtKB=Q4QJ50	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.7.4930\|UniProtKB=Q57XA9	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_34134\|UniProtKB=A8B979	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_427300\|UniProtKB=A2FNB2	Trichomonas vaginalis	LDO
PHYRM\|Gene=H3GUN4_PHYRM\|UniProtKB=H3GUN4	Phytophthora ramorum	O
PHYRM\|Gene=H3GUN6_PHYRM\|UniProtKB=H3GUN6	Phytophthora ramorum	O
PHYRM\|Gene=H3H652_PHYRM\|UniProtKB=H3H652	Phytophthora ramorum	O
PHYRM\|Gene=H3GUN7_PHYRM\|UniProtKB=H3GUN7	Phytophthora ramorum	LDO
SELML\|EnsemblGenome=SELMODRAFT_427944\|UniProtKB=D8T173	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_414436\|UniProtKB=D8RSR9	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_409945\|UniProtKB=D8RCZ1	Selaginella moellendorffii	LDO
CHLAA\|EnsemblGenome=Caur_1275\|UniProtKB=A9WK52	Chloroflexus aurantiacus	LDO
CLOBH\|Gene_OrderedLocusName=CBO0402\|UniProtKB=A5HYU6	Clostridium botulinum	LDO
THEMA\|EnsemblGenome=TM_1296\|UniProtKB=Q9X122	Thermotoga maritima	LDO
DEIRA\|EnsemblGenome=DR_0899\|UniProtKB=Q9RVX2	Deinococcus radiodurans	LDO
SYNY3\|EnsemblGenome=BAA10553\|UniProtKB=Q55801	Synechocystis	LDO
RHOBA\|EnsemblGenome=RB10271\|UniProtKB=Q7UF86	Rhodopirellula baltica	LDO
HELPY\|EnsemblGenome=HP_0661\|UniProtKB=P56120	Helicobacter pylori	LDO
NEIMB\|EnsemblGenome=NMB1618\|UniProtKB=Q9JYE5	Neisseria meningitidis serogroup b	LDO
GEOSL\|EnsemblGenome=GSU2071\|UniProtKB=Q74BH0	Geobacter sulfurreducens	LDO
BRADU\|EnsemblGenome=BAC46581\|UniProtKB=Q89UU3	Bradyrhizobium diazoefficiens	LDO
COXBU\|EnsemblGenome=CBU_0316\|UniProtKB=Q83EK3	Coxiella burnetii	LDO
HAEIN\|EnsemblGenome=HI_0138\|UniProtKB=P43807	Haemophilus influenzae	LDO
SHEON\|Gene_OrderedLocusName=SO_2560\|UniProtKB=Q8EE30	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_0498\|UniProtKB=Q9KUL7	Vibrio cholerae	O
VIBCH\|EnsemblGenome=VC_2234\|UniProtKB=Q9KPX8	Vibrio cholerae	LDO
XANCP\|EnsemblGenome=XCC0987\|UniProtKB=Q8PBX8	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA1815\|UniProtKB=Q9I2S9	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM0263\|UniProtKB=P0A2B9	Salmonella typhimurium	LDO
YERPE\|EnsemblGenome=YP_2768\|UniProtKB=Q8ZH30	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAA77885\|UniProtKB=P0A7Y4	Escherichia coli	LDO