PANTHER Gene Information

Gene Symbol(s):

PAM

Organism:

Macaca mulatta

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Gene Name:

Peptidyl-glycine alpha-amidating monooxygenase isoform a preproprotein

Gene ID:

ENSMMUG00000007844.4

Protein ID:

I0FS58

Persistent Id:

PTN000840921

Alternate Ids:

966947948(GI)	ENSMMUP00000071213(Ensembl_PRO)
XP_014995981(refSeq)	ENSMMUG00000007844(Ensembl)
I0FS58_MACMU(UniProtKB-ID)	JV047213(EMBL)
AFI37284(EMBL-CDS)	707733(GeneID)
ENSMMUT00000088391(Ensembl_TRS)	I0FS58(Synonym)
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PANTHER Classification

PANTHER Family:	PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE (PTHR10680)
PANTHER Subfamily:	PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE (PTHR10680:SF14)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	oxygenase

Pathway Categories:

Vasopressin synthesis

Amidating Enzyme

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	L-ascorbic acid binding, peptidylglycine monooxygenase activity, zinc ion binding, copper ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen, metal ion binding, lyase activity, monooxygenase activity, peptidylamidoglycolate lyase activity
GO BP Complete:	response to zinc ion, peptide metabolic process, peptide amidation
GO CC Complete:	transport vesicle membrane, membrane, cytoplasmic vesicle, extracellular region

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=8596\|UniProtKB=P19021	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000017110.7\|UniProtKB=H2R5G8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000009306.3\|UniProtKB=G3R1M8	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=97475\|UniProtKB=P97467	Mus musculus	LDO
RAT\|RGD=3252\|UniProtKB=P14925	Rattus norvegicus	LDO
BOVIN\|Gene=PAM\|UniProtKB=P10731	Bos taurus	LDO
BOVIN\|Ensembl=ENSBTAG00000012387.5\|UniProtKB=F1MZB4	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000014184.5\|UniProtKB=A0A287A5G2	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000021895.4\|UniProtKB=A0A5F5PQU7	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000006174.6\|UniProtKB=A0A337S9K0	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845001601.1\|UniProtKB=A0A8I3MKY9	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000019284.4\|UniProtKB=F6SHA5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000005452.4\|UniProtKB=F7C320	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010008497.1\|UniProtKB=A0A8V0XU79	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000006978.4\|UniProtKB=A0A803TAJ3	Anolis carolinensis	LDO
XENLA\|Gene=pam.S\|UniProtKB=A0A8J0TIY7	Xenopus laevis	O
XENLA\|Gene=pam.L\|UniProtKB=A0A1L8I1N5	Xenopus laevis	LDO
XENLA\|Gene=pam-b\|UniProtKB=P12890	Xenopus laevis	O
XENLA\|Gene=pam-a\|UniProtKB=P08478	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-950935\|UniProtKB=A0A8J0QFI1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000026325.1\|UniProtKB=A0A3B3H429	Oryzias latipes	LDO
DANRE\|Gene=pam\|UniProtKB=A0A8M2B2D2	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000009107.1\|UniProtKB=W5MRU9	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000008854.4\|UniProtKB=F6R3M6	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118407715\|UniProtKB=A0A9J7HTI0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118407264\|UniProtKB=A0A9J7HQH1	Branchiostoma floridae	LDO
BRAFL\|Gene=LOC118410160\|UniProtKB=A0A9J7KP40	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC579753\|UniProtKB=A0A7M7N970	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC580829\|UniProtKB=A0A7M7RE30	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00020556\|UniProtKB=P83388	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG14919\|UniProtKB=A8XKZ9	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00202713\|UniProtKB=A0A8R1YNK6	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0283509\|UniProtKB=O01404	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP007420\|UniProtKB=Q7QJC8	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC007292\|UniProtKB=D2A0D2	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_63619\|UniProtKB=E9HK95	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_330720\|UniProtKB=E9HKF4	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_68861\|UniProtKB=E9I2S2	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_225477\|UniProtKB=E9GQS1	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_307337\|UniProtKB=E9H1V4	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG90150\|UniProtKB=T1G7L7	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g101809\|UniProtKB=A7S2F4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g172604\|UniProtKB=A7SNT2	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG63754\|UniProtKB=B3RS62	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_32755\|UniProtKB=A9V1I8	Monosiga brevicollis	LDO
CHLRE\|EnsemblGenome=CHLRE_03g152850v5\|UniProtKB=A0A0S2C767	Chlamydomonas reinhardtii	LDO