PANTHER Gene Information

Gene Symbol(s):

OPRL1

Organism:

Macaca mulatta

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Tree

Gene Name:

Nociceptin receptor

Gene ID:

ENSMMUG00000043739.2

Protein ID:

H9EUZ6

Persistent Id:

PTN002796205

Alternate Ids:

H9EUZ6(Synonym)	ENSMMUP00000044226(Ensembl_PRO)
719224(GeneID)	AFE66205(EMBL-CDS)
ENSMMUT00000102157(Ensembl_TRS)	NP_001307544(refSeq)
ENSMMUG00000043739(Ensembl)	JU322449(EMBL)
H9EUZ6_MACMU(UniProtKB-ID)	1002013752(GI)
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PANTHER Classification

PANTHER Family:	NEUROPEPTIDES RECEPTOR (PTHR24229)
PANTHER Subfamily:	NOCICEPTIN RECEPTOR (PTHR24229:SF11)
PANTHER GO-slim Molecular Function:	G protein-coupled peptide receptor activity neuropeptide binding
PANTHER GO-slim Biological Process:	sensory perception neuropeptide signaling pathway
PANTHER GO-slim Cellular Component:	plasma membrane neuron projection
PANTHER protein class:	G-protein coupled receptor

Pathway Categories:

Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway

Gi protein coupled receptor

Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway

Go-protein coupled receptor

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	G protein-coupled receptor activity, neuropeptide binding, nociceptin receptor activity
GO BP Complete:	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, G protein-coupled opioid receptor signaling pathway, neuropeptide signaling pathway, G protein-coupled receptor signaling pathway, sensory perception of pain, phospholipase C-activating G protein-coupled receptor signaling pathway, calcium-mediated signaling
GO CC Complete:	membrane, cytoplasmic vesicle, neuron projection, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=8155\|UniProtKB=P41146	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000049284.1\|UniProtKB=A0A2I3SM21	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000024482.2\|UniProtKB=G3RX55	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=97440\|UniProtKB=P35377	Mus musculus	LDO
RAT\|RGD=68438\|UniProtKB=P35370	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000049473.1\|UniProtKB=A0A3Q1LTY9	Bos taurus	LDO
PIG\|Gene=OPRL1\|UniProtKB=P79292	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000031228.3\|UniProtKB=A0A287ABF9	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000010767.4\|UniProtKB=A0A9L0T4T9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000001187.5\|UniProtKB=M3VW58	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000017068.4\|UniProtKB=F6XHC9	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000050101.1\|UniProtKB=A0A6I8NAG3	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010023269.1\|UniProtKB=R4GF58	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000043781.1\|UniProtKB=A0A803SYE6	Anolis carolinensis	LDO
XENLA\|Gene=oprl1.L\|UniProtKB=A0A8J0QHS1	Xenopus laevis	O
XENLA\|Gene=oprl1.S\|UniProtKB=A0A8J0QFM3	Xenopus laevis	LDO
XENTR\|Ensembl=ENSXETG00000042619\|UniProtKB=A0A803K7R9	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000026714.1\|UniProtKB=A0A3B3ICN6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-091118-42\|UniProtKB=A0A8M9PE56	Danio rerio	O
DANRE\|Gene=oprl1\|UniProtKB=A0A8M1P286	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000005285.1\|UniProtKB=W5MDC9	lepisosteus oculatus	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_88027\|UniProtKB=C3YC95	Branchiostoma floridae	O
BRAFL\|Gene=LOC118428375\|UniProtKB=A0A9J7M577	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC100894075\|UniProtKB=A0A7M7LVT1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115918792\|UniProtKB=A0A7M7P664	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100890211\|UniProtKB=A0A7M7GKD6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115922676\|UniProtKB=A0A7M7NQ32	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115926735\|UniProtKB=A0A7M7T1W2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100888551\|UniProtKB=A0A7M7NHJ1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100893852\|UniProtKB=A0A7M7GFS5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105439709\|UniProtKB=A0A7M7N436	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC578807\|UniProtKB=A0A7M7LVY3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115918122\|UniProtKB=A0A7M7NM54	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC752674\|UniProtKB=A0A7M7HK66	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115918536\|UniProtKB=A0A7M7NL69	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100893370\|UniProtKB=A0A7M7HDG8	Strongylocentrotus purpuratus	O
DROME\|FlyBase=FBgn0266429\|UniProtKB=Q9U721	Drosophila melanogaster	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_60654\|UniProtKB=E9HB05	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG141773\|UniProtKB=T1EJ41	helobdella robusta	O
CAEEL\|WormBase=WBGene00008065\|UniProtKB=Q09502	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG16052\|UniProtKB=A8XN72	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00089848\|UniProtKB=A0A2A6BFS4	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00006864\|UniProtKB=A0A3B1DQQ4	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00034796\|UniProtKB=A8XJK0	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00103481\|UniProtKB=A0A2A6CEY4	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00010375\|UniProtKB=H9G358	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG09656\|UniProtKB=A8X8J4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00273154\|UniProtKB=A0A2A6C5M8	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00008885\|UniProtKB=Q9XVQ0	Caenorhabditis elegans	O
PRIPA\|EnsemblGenome=WBGene00277584\|UniProtKB=A0A2A6CGK0	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00092761\|UniProtKB=A0A2A6BNC7	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00011372\|UniProtKB=A0A0K3AXD3	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG00382\|UniProtKB=A8WMY5	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00202780\|UniProtKB=A0A2A6BYV3	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00018886\|UniProtKB=Q20841	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00041241\|UniProtKB=A8Y333	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00109898\|UniProtKB=A0A2A6CUK6	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00015559\|UniProtKB=P34311	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG22950\|UniProtKB=A8Y3L2	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00091461\|UniProtKB=A0A2A6CA63	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00204108\|UniProtKB=A0A2A6BQK5	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00021328\|UniProtKB=Q9N452	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00040713\|UniProtKB=A8Y1H4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00094433\|UniProtKB=A0A2A6CEL5	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00018089\|UniProtKB=A0A2C9C3A4	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG19271\|UniProtKB=A8XV84	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00107613\|UniProtKB=A0A2A6C5V7	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00020086\|UniProtKB=Q23033	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00025042\|UniProtKB=A8WRG4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00117000\|UniProtKB=A0A8R1UIE8	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0036260\|UniProtKB=Q9VTU7	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007548\|UniProtKB=Q7QJJ6	Anopheles gambiae	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_346935\|UniProtKB=E9HBX2	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_346930\|UniProtKB=E9HBW5	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW004568\|UniProtKB=B7PJM1	Ixodes scapularis	O
DROME\|FlyBase=FBgn0036790\|UniProtKB=Q9VVQ1	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0036789\|UniProtKB=A0A0S0WMT8	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP010486\|UniProtKB=A0A1S4H448	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP012268\|UniProtKB=A0A1S4H9R6	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC002068\|UniProtKB=D7EIU6	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC034475\|UniProtKB=A0A139WC60	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC033099\|UniProtKB=A0A139WID0	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC034476\|UniProtKB=A0A139WC11	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC033098\|UniProtKB=A0A139WIL7	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC011633\|UniProtKB=D6X0Z7	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC012842\|UniProtKB=D6X173	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_12571\|UniProtKB=E9H6K4	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_12576\|UniProtKB=E9H6K3	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW007666\|UniProtKB=B7PU05	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG181659\|UniProtKB=T1FH76	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG82100\|UniProtKB=T1G4M7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG130073\|UniProtKB=T1EHT0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG122299\|UniProtKB=T1EGU4	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g205366\|UniProtKB=A7S1I8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g224862\|UniProtKB=A7TBI0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g246081\|UniProtKB=A7SLS4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g214252\|UniProtKB=A7SLS3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g209052\|UniProtKB=A7S9Z8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g222485\|UniProtKB=A7T577	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g203549\|UniProtKB=A7RXC3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g214208\|UniProtKB=A7SLN8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g213211\|UniProtKB=A7SJG8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g209053\|UniProtKB=A7S9Z9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g200474\|UniProtKB=A7RQ77	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g209220\|UniProtKB=A7SAD6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g221896\|UniProtKB=A7T3P5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g246083\|UniProtKB=A7SLS6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g225244\|UniProtKB=A7TCH5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g207414\|UniProtKB=A7S662	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG60078\|UniProtKB=B3S787	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG57575\|UniProtKB=B3RZT9	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG56035\|UniProtKB=B3RTT0	Trichoplax adhaerens	O
BATDJ\|Gene_ORFName=BATDEDRAFT_86491\|UniProtKB=F4NXJ2	Batrachochytrium dendrobatidis	O