PANTHER Gene Information

Gene Symbol(s):

NKX3-2

Organism:

Macaca mulatta

View Gene in Tree

Tree

Gene Name:

NK3 homeobox 2

Gene ID:

ENSMMUG00000062096.1

Protein ID:

A0A5F7ZYG7

Persistent Id:

PTN008401125

Alternate Ids:

ENSMMUT00000104275(Ensembl_TRS)	A0A5F7ZYG7_MACMU(UniProtKB-ID)
713627(GeneID)	A0A5F7ZYG7(Synonym)
ENSMMUP00000070674(Ensembl_PRO)	ENSMMUG00000062096(Ensembl)
302564363(GI)	NP_001181040(refSeq)
Show All

PANTHER Classification

PANTHER Family:	HOMEOBOX PROTEIN NKX (PTHR24340)
PANTHER Subfamily:	HOMEOBOX PROTEIN NKX-3.2 (PTHR24340:SF34)
PANTHER GO-slim Molecular Function:	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process:	cell differentiation regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	homeodomain transcription factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	DNA binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription repressor activity, RNA polymerase II-specific, sequence-specific double-stranded DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	regulation of DNA-templated transcription, middle ear morphogenesis, spleen development, animal organ development, animal organ formation, embryonic skeletal system development, intestinal epithelial cell development, skeletal system morphogenesis, determination of left/right symmetry, regulation of transcription by RNA polymerase II, negative regulation of transcription by RNA polymerase II, skeletal system development, negative regulation of apoptotic process, cell differentiation, digestive system development, negative regulation of chondrocyte differentiation, pancreas development
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=951\|UniProtKB=P78367	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000048496.1\|UniProtKB=K7A5T9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000008589.3\|UniProtKB=G3QZS9	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=108015\|UniProtKB=P97503	Mus musculus	LDO
RAT\|RGD=1584617\|UniProtKB=A0A0G2JZE5	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000010896.4\|UniProtKB=E1B710	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000034181.3\|UniProtKB=A0A286ZVB8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000027948.3\|UniProtKB=A0A3Q2I609	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000033775.3\|UniProtKB=A0A2I2USB6	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845002262.1\|UniProtKB=A0A8I3MKP2	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000043621.1\|UniProtKB=A0A5F8GYS1	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010010183.1\|UniProtKB=A0A8V0Y4A6	Gallus gallus	LDO
XENLA\|Gene=nkx3-3.L\|UniProtKB=A0A1L8FJH8	Xenopus laevis	O
XENLA\|Gene=zax\|UniProtKB=O93590	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-479908\|UniProtKB=A0A6I8SEA3	Xenopus tropicalis	O
XENLA\|Gene=nkx3-2\|UniProtKB=P70061	Xenopus laevis	O
XENLA\|Gene=nkx3-2.L\|UniProtKB=A0A1L8HTD2	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-876834\|UniProtKB=A0A6I8R8A6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000007716.2\|UniProtKB=H2LU88	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000029707.1\|UniProtKB=A0A3B3H2Y8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050306-27\|UniProtKB=F1R3M6	Danio rerio	O
DANRE\|Gene=nkx3-1\|UniProtKB=A0A8N7TAH9	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-030127-1\|UniProtKB=Q803Z6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000009031.1\|UniProtKB=W5MRJ5	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000009892.1\|UniProtKB=W5MUM8	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000007395.3\|UniProtKB=F6UL80	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_290584\|UniProtKB=C3XZP6	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC579532\|UniProtKB=A0A7M7RG65	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0000576\|UniProtKB=P18488	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0004862\|UniProtKB=P22809	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP003671\|UniProtKB=Q7QAJ4	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC012743\|UniProtKB=D6WZY4	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_25304\|UniProtKB=E9G181	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW014989\|UniProtKB=A0A1S4LJI6	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g208034\|UniProtKB=A7S7L1	Nematostella vectensis	LDO