PANTHER Gene Information

Gene Symbol(s):

11434137

Organism:

Medicago truncatula

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Gene Name:

NAD-dependent isocitrate dehydrogenase

Gene ID:

MTR_1g064070

Protein ID:

G7IAA3

Persistent Id:

PTN004312478

Alternate Ids:

XM_003590421(refSeq)	355479517(GI)
G7IAA3_MEDTR(UniProtKB-ID)	PSQE01000001(EMBL)
G7IAA3(Synonym)	11434137(GeneID)
MTR_1g064070(Ensembl)	AES60720(EMBL-CDS)
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PANTHER Classification

PANTHER Family:	DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE (PTHR11835)
PANTHER Subfamily:	ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL (PTHR11835:SF34)
PANTHER GO-slim Molecular Function:	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
PANTHER GO-slim Biological Process:	secondary alcohol metabolic process tricarboxylic acid cycle carboxylic acid metabolic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	dehydrogenase

Pathway Categories:

Leucine biosynthesis

3-Isopropylmalate dehydrogenase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	magnesium ion binding, isocitrate dehydrogenase (NAD+) activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, oxidoreductase activity, metal ion binding, NAD binding
GO BP Complete:	isocitrate metabolic process, tricarboxylic acid cycle, carboxylic acid metabolic process
GO CC Complete:	mitochondrion

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
IXOSC\|EnsemblGenome=ISCW016729\|UniProtKB=B7P8B1	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g226098\|UniProtKB=A8DWU0	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_31232\|UniProtKB=A9USI1	Monosiga brevicollis	O
HUMAN\|HGNC=5384\|UniProtKB=P50213	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000007336.6\|UniProtKB=H2Q9W0	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000002227.3\|UniProtKB=A0A2I2ZTP2	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000011838.4\|UniProtKB=I2CW30	Macaca mulatta	O
MOUSE\|MGI=MGI=1915084\|UniProtKB=Q9D6R2	Mus musculus	O
RAT\|RGD=70889\|UniProtKB=Q99NA5	Rattus norvegicus	O
BOVIN\|Gene=IDH3A\|UniProtKB=P41563	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000006227.4\|UniProtKB=Q148J8	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000032498.3\|UniProtKB=A0A480S312	Sus scrofa	O
PIG\|Gene=IDH3A\|UniProtKB=P56471	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000015278.4\|UniProtKB=A0A9L0SWI4	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000010515.5\|UniProtKB=M3WDF0	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845006975.1\|UniProtKB=A0A8I3NG17	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000011642.3\|UniProtKB=F6TJ83	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000014728.4\|UniProtKB=F7EQJ8	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010024322.1\|UniProtKB=A0A8V1A4J0	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000006101.4\|UniProtKB=H9GB07	Anolis carolinensis	O
XENLA\|Gene=idh3a.L\|UniProtKB=A0A8J0URS2	Xenopus laevis	O
XENLA\|Gene=idh3a.S\|UniProtKB=A0A8J0UMM0	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-943186\|UniProtKB=Q6P314	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000027001.1\|UniProtKB=A0A3B3H4B4	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040426-1007\|UniProtKB=Q6NV33	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000014826.1\|UniProtKB=W5NCA0	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000007286.3\|UniProtKB=F6SUS9	Ciona intestinalis	O
BRAFL\|Gene=LOC118410079\|UniProtKB=A0A9J7KP58	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC587700\|UniProtKB=A0A7M7TGX8	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00009664\|UniProtKB=Q93714	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00033447\|UniProtKB=A8XFX3	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00278357\|UniProtKB=A0A2A6CCQ7	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0035005\|UniProtKB=Q9W172	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0052026\|UniProtKB=Q8T0R3	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0027291\|UniProtKB=Q9VWH4	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP002728\|UniProtKB=F5HKN6	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC004962\|UniProtKB=D6WCZ6	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_222251\|UniProtKB=E9G2H1	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW004116\|UniProtKB=B7PHM9	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG185474\|UniProtKB=T1FMV2	helobdella robusta	O
TRIAD\|EnsemblGenome=TriadG54615\|UniProtKB=B3RSJ1	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_19354\|UniProtKB=A9UQS3	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_6048\|UniProtKB=A9URF0	Monosiga brevicollis	O
YEAST\|SGD=S000001356\|UniProtKB=P40495	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ADL214C\|UniProtKB=Q75AY4	Eremothecium gossypii	O
CANAL\|CGD=CAL0000198832\|UniProtKB=Q5A9D9	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_D10593g\|UniProtKB=Q6C9K0	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_05206\|UniProtKB=G5EB15	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_6G07390\|UniProtKB=Q4WN70	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU02954\|UniProtKB=Q7SH15	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_02537\|UniProtKB=A7EB51	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_01047\|UniProtKB=Q0V4L7	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC31G5.04\|UniProtKB=O14104	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_00502\|UniProtKB=B6JVT5	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CND03850\|UniProtKB=Q5KI84	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_04873\|UniProtKB=A0A0D1CIK8	Ustilago maydis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_85530\|UniProtKB=F4NTN8	Batrachochytrium dendrobatidis	O
YEAST\|SGD=S000005662\|UniProtKB=P28241	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AFR137C\|UniProtKB=Q754D3	Eremothecium gossypii	O
CANAL\|CGD=CAL0000183793\|UniProtKB=A0A1D8PGS5	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_D06303g\|UniProtKB=Q6CA33	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_01003\|UniProtKB=C8VU63	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G12800\|UniProtKB=E9QYY1	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU07697\|UniProtKB=Q7S9K8	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_09958\|UniProtKB=A7EX97	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_06082\|UniProtKB=Q0UQ82	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC902.05c\|UniProtKB=Q9USP8	Schizosaccharomyces pombe	O
CRYNJ\|EnsemblGenome=CNA04610\|UniProtKB=Q5KP10	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_01328\|UniProtKB=A0A0D1E633	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_01926\|UniProtKB=E3JTK8	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_33391\|UniProtKB=F4P5V7	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0271344\|UniProtKB=Q55BI2	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_80730\|UniProtKB=F0ZRC6	Dictyostelium purpureum	O
PARTE\|EnsemblGenome=GSPATT00023050001\|UniProtKB=A0E3L0	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00025896001\|UniProtKB=A0EE35	Paramecium tetraurelia	O
CHLRE\|EnsemblGenome=CHLRE_02g143250v5\|UniProtKB=A0A2K3E3Z0	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00001p00200380\|UniProtKB=W1NLC5	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_307G00010\|UniProtKB=A0A0K9PC97	Zostera marina	O
MUSAM\|EnsemblGenome=Ma10_g11000\|UniProtKB=A0A804KUW6	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma06_g14450\|UniProtKB=A0A804JG73	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_001950mg\|UniProtKB=K3XJ77	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3003G129900\|UniProtKB=C5XH85	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb332780\|UniProtKB=B6TJM1	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb128830\|UniProtKB=B4FAD4	Zea mays	O
ORYSJ\|EnsemblGenome=Os01g0276100\|UniProtKB=Q9SDG5	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g43300v3\|UniProtKB=I1I9M7	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0209680\|UniProtKB=G9AYJ6	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS2B02G592100\|UniProtKB=W5BEC0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2A02G591600\|UniProtKB=A0A3B6B9T4	Triticum aestivum	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0586240\|UniProtKB=A0A287U3J5	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS6B02G235000\|UniProtKB=A0A3B6PLE4	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G198200\|UniProtKB=A0A3B6NR24	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G183400\|UniProtKB=A0A3B6QE47	Triticum aestivum	O
NELNU\|Gene=LOC104601278\|UniProtKB=A0A1U8AKP2	Nelumbo nucifera	O
NELNU\|Gene=LOC104599244\|UniProtKB=A0A1U8ACV7	Nelumbo nucifera	O
SPIOL\|Gene=LOC110796048\|UniProtKB=A0A9R0IW93	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr01g0040221\|UniProtKB=A0A251VT73	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr11g0514991\|UniProtKB=A0A251TEL2	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C100021770\|UniProtKB=A0A9R1WCP8	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a025927mg\|UniProtKB=A0A022R4D0	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a008944mg\|UniProtKB=A0A022R3E5	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a008537mg\|UniProtKB=A0A022RDV5	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_06457\|UniProtKB=A0A2G3AAU7	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_06338\|UniProtKB=A0A2G3AAI2	Capsicum annuum	O
SOLTU\|Gene=LEU3_SOLTU\|UniProtKB=P29696	Solanum tuberosum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400026246\|UniProtKB=M1CHE3	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc08g077920.3\|UniProtKB=A0A3Q7HUE5	Solanum lycopersicum	O
TOBAC\|Gene=LOC107813330\|UniProtKB=A0A1S4BYT9	Nicotiana tabacum	O
TOBAC\|Gene=LOC107814521\|UniProtKB=A0A1S4C2Z5	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi08g01021\|UniProtKB=D7TQM9	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_A01135\|UniProtKB=A0A059DEF9	Eucalyptus grandis	O
BRANA\|Gene_ORFName=GSBRNA2T00080711001\|UniProtKB=A0A078I3T9	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C05P58310.1\|UniProtKB=A0A078HW36	Brassica napus	O
BRACM\|EnsemblGenome=Bra029791\|UniProtKB=M4ELX1	Brassica campestris	O
ARATH\|TAIR=locus=2074939\|UniProtKB=Q8LG77	Arabidopsis thaliana	O
BRANA\|Gene_ORFName=GSBRNA2T00080014001\|UniProtKB=A0A078I5B6	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00037726001\|UniProtKB=A0A078JB58	Brassica napus	O
BRACM\|EnsemblGenome=Bra028843\|UniProtKB=M4EJ77	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_C09P73490.1\|UniProtKB=A0A078FAF4	Brassica napus	O
BRACM\|EnsemblGenome=Bra009537\|UniProtKB=A0A397XQZ6	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_A03P01100.1\|UniProtKB=A0A078FD30	Brassica napus	O
BRACM\|EnsemblGenome=Bra005736\|UniProtKB=M4CNE8	Brassica campestris	O
ARATH\|TAIR=locus=2142604\|UniProtKB=Q945K7	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107891139\|UniProtKB=A0A1U8I6E6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107943579\|UniProtKB=A0A1U8N4S6	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_022180\|UniProtKB=A0A061ETX7	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g017413mg\|UniProtKB=A0A067E9Z4	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_006G126700v3\|UniProtKB=A0A2K2A1A6	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_016G091200v3\|UniProtKB=B9IFP1	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_09G063800\|UniProtKB=A0A2C9V8F3	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_08G008500\|UniProtKB=A0A2C9VDL7	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1355470\|UniProtKB=B9S0K1	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_13G144900\|UniProtKB=I1LZ93	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_10G058100\|UniProtKB=I1L903	Glycine max	O
JUGRE\|EnsemblGenome=Jr04_04470\|UniProtKB=A0A2I4H5Q2	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_6G446300\|UniProtKB=A0A0A0KF41	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_6G235200\|UniProtKB=M5VYP8	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_160113\|UniProtKB=D8T1A5	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_233612\|UniProtKB=D8SC18	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c9_16040\|UniProtKB=A0A2K1K3E4	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c15_3920\|UniProtKB=A9SIP7	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c9_4370\|UniProtKB=A9TBJ2	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0002s0215\|UniProtKB=A0A2R6XUH9	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_000230270\|UniProtKB=A0A1Y1HT94	Klebsormidium nitens	O
NITMS\|EnsemblGenome=Nmar_1379\|UniProtKB=A9A2N6	Nitrosopumilus maritimus	O
METAC\|EnsemblGenome=MA_4265\|UniProtKB=Q8TI91	Methanosarcina acetivorans	O
NITMS\|EnsemblGenome=Nmar_1069\|UniProtKB=A9A4I7	Nitrosopumilus maritimus	O
KORCO\|EnsemblGenome=Kcr_0970\|UniProtKB=B1L5I7	Korarchaeum cryptofilum	O
KORCO\|EnsemblGenome=Kcr_0190\|UniProtKB=B1L3C1	Korarchaeum cryptofilum	O
SACS2\|EnsemblGenome=SSO0723\|UniProtKB=Q9UXB2	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE1995\|UniProtKB=Q8ZW34	Pyrobaculum aerophilum	O
METAC\|EnsemblGenome=MA_3748\|UniProtKB=Q8TJN2	Methanosarcina acetivorans	O
METJA\|EnsemblGenome=MJ_1596\|UniProtKB=Q58991	Methanocaldococcus jannaschii	O
METJA\|EnsemblGenome=MJ_0720\|UniProtKB=Q58130	Methanocaldococcus jannaschii	O
THEKO\|EnsemblGenome=TK0280\|UniProtKB=Q5JFV8	Thermococcus kodakaraensis	O
CHLAA\|EnsemblGenome=Caur_0331\|UniProtKB=A9WD13	Chloroflexus aurantiacus	O
CLOBH\|Gene_OrderedLocusName=CBO0419\|UniProtKB=A5HYW3	Clostridium botulinum	O
DEIRA\|EnsemblGenome=DR_1674\|UniProtKB=Q9RTT2	Deinococcus radiodurans	O
GLOVI\|Gene=icd\|UniProtKB=Q7NC91	Gloeobacter violaceus	O
THEYD\|EnsemblGenome=THEYE_A1278\|UniProtKB=B5YFP4	Thermodesulfovibrio yellowstonii	O
BRADU\|Gene=Q89RJ1_BRADU\|UniProtKB=Q89RJ1	Bradyrhizobium diazoefficiens	O
BRADU\|Gene=Q89RM2_BRADU\|UniProtKB=Q89RM2	Bradyrhizobium diazoefficiens	O
BRADU\|Gene=leuB\|UniProtKB=Q89GM4	Bradyrhizobium diazoefficiens	O
SHEON\|Gene_OrderedLocusName=SO_1538\|UniProtKB=Q8EGQ7	Shewanella oneidensis	O
XANCP\|EnsemblGenome=XCC0967\|UniProtKB=Q8PBY9	Xanthomonas campestris	O