PANTHER Gene Information

Gene Symbol(s):

hisB

Organism:

Methanosarcina acetivorans

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Gene Name:

Imidazoleglycerol-phosphate dehydratase

Gene ID:

MA_0219

Protein ID:

P58878

Persistent Id:

PTN000566232

Alternate Ids:

1472111(GeneID)	AAM03672(Ensembl_TRS)
IGPD {ECO:0000255\|HAMAP-Rule:MF_00076}(Synonym)	AAM03672(Ensembl_PRO)
AE010299(EMBL)	hisB{ECO:0000255\|HAMAP-Rule:MF_00076}(Symbol)
MA_0219(Ensembl)	AAM03672(EMBL-CDS)
4.2.1.19 {ECO:0000255\|HAMAP-Rule:MF_00076}(EC)	19913983(GI)
HIS7_METAC(UniProtKB-ID)	WP_011020277(refSeq)
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PANTHER Classification

PANTHER Family:	IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE HIS7 (PTHR23133)
PANTHER Subfamily:	IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE (PTHR23133:SF2)
PANTHER GO-slim Molecular Function:	hydro-lyase activity
PANTHER GO-slim Biological Process:	amino acid biosynthetic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	dehydratase

Pathway Categories:

Histidine biosynthesis

Imidazol glycerol phosphate dehydratase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	imidazoleglycerol-phosphate dehydratase activity, lyase activity
GO BP Complete:	L-histidine biosynthetic process
GO CC Complete:	cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
MONBE\|EnsemblGenome=MONBRDRAFT_2754\|UniProtKB=A9UP39	Monosiga brevicollis	LDO
YEAST\|SGD=S000005728\|UniProtKB=P06633	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_ADL270C\|UniProtKB=Q75B47	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000187142\|UniProtKB=Q59LL5	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E33957g\|UniProtKB=Q6C3L0	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_06536\|UniProtKB=Q5AYU4	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_6G04700\|UniProtKB=Q4WDG8	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU01300\|UniProtKB=Q9HEG3	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_00435\|UniProtKB=A7E563	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_09369\|UniProtKB=Q0UFU5	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC21H7.07c\|UniProtKB=P40374	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_00592\|UniProtKB=B6JW23	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNH01620\|UniProtKB=P0CO22	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_11859\|UniProtKB=A0A0D1E5D5	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_08188\|UniProtKB=E3KCJ1	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_10598\|UniProtKB=F4P002	Batrachochytrium dendrobatidis	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_33348\|UniProtKB=B8C0Y0	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G8Y9_PHYRM\|UniProtKB=H3G8Y9	Phytophthora ramorum	LDO
NITMS\|EnsemblGenome=Nmar_1555\|UniProtKB=A9A5X3	Nitrosopumilus maritimus	LDO
SACS2\|EnsemblGenome=SSO0596\|UniProtKB=O33773	Sulfolobus solfataricus	LDO
PYRAE\|EnsemblGenome=PAE0990\|UniProtKB=Q8ZY15	Pyrobaculum aerophilum	LDO
METJA\|EnsemblGenome=MJ_0698\|UniProtKB=Q58109	Methanocaldococcus jannaschii	LDO
HALSA\|EnsemblGenome=VNG_2295G\|UniProtKB=Q9HN13	Halobacterium salinarum	LDO
THEKO\|EnsemblGenome=TK0245\|UniProtKB=Q5JFT0	Thermococcus kodakaraensis	LDO
CHLAA\|EnsemblGenome=Caur_1935\|UniProtKB=A9WDZ1	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO2052\|UniProtKB=P16247	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv1601\|UniProtKB=P9WML9	Mycobacterium tuberculosis	LDO
CLOBH\|Gene_OrderedLocusName=CBO1568\|UniProtKB=A5I242	Clostridium botulinum	LDO
STAA8\|EnsemblGenome=SAOUHSC_03011\|UniProtKB=Q2FUU0	Staphylococcus aureus	LDO
LISMO\|EnsemblGenome=CAC98645\|UniProtKB=Q8Y9G2	Listeria monocytogenes	LDO
BACSU\|EnsemblGenome=BSU_34900\|UniProtKB=O34683	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_1407\|UniProtKB=Q81G05	Bacillus cereus	LDO
THEMA\|EnsemblGenome=TM_1039\|UniProtKB=Q9X0C9	Thermotoga maritima	LDO
DEIRA\|EnsemblGenome=DR_0424\|UniProtKB=Q9RX91	Deinococcus radiodurans	LDO
GLOVI\|EnsemblGenome=BAC88710\|UniProtKB=Q7NMJ6	Gloeobacter violaceus	LDO
SYNY3\|EnsemblGenome=BAA10571\|UniProtKB=P48054	Synechocystis	LDO
LEPIN\|EnsemblGenome=LA_0124\|UniProtKB=Q8F9R6	Leptospira interrogans	LDO
BACTN\|EnsemblGenome=BT_0203\|UniProtKB=Q8ABA7	Bacteroides thetaiotaomicron	LDO
RHOBA\|EnsemblGenome=RB7662\|UniProtKB=Q7UNC2	Rhodopirellula baltica	LDO
AQUAE\|EnsemblGenome=aq_039\|UniProtKB=O66455	Aquifex aeolicus	LDO
THEYD\|EnsemblGenome=THEYE_A0970\|UniProtKB=B5YKN8	Thermodesulfovibrio yellowstonii	LDO
DICTD\|EnsemblGenome=Dtur_1123\|UniProtKB=B8E2C5	Dictyoglomus turgidum	LDO
NEIMB\|EnsemblGenome=NMB1583\|UniProtKB=P64371	Neisseria meningitidis serogroup b	LDO
GEOSL\|EnsemblGenome=GSU3098\|UniProtKB=P60885	Geobacter sulfurreducens	LDO
BRADU\|EnsemblGenome=BAC45915\|UniProtKB=Q89WM8	Bradyrhizobium diazoefficiens	LDO
HAEIN\|EnsemblGenome=HI_0471\|UniProtKB=P44327	Haemophilus influenzae	LDO
SHEON\|Gene_OrderedLocusName=SO_2071\|UniProtKB=Q8EFB3	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_1135\|UniProtKB=Q9KSX1	Vibrio cholerae	LDO
XANCP\|EnsemblGenome=XCC1811\|UniProtKB=P58882	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA5143\|UniProtKB=Q9HU41	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM2074\|UniProtKB=P10368	Salmonella typhimurium	LDO
YERPE\|EnsemblGenome=YP_1435\|UniProtKB=Q8ZFX7	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAA15853\|UniProtKB=P06987	Escherichia coli	LDO