PANTHER Gene Information

Gene Symbol(s):

MARK2

Organism:

Monodelphis domestica

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Gene Name:

Microtubule affinity regulating kinase 2

Gene ID:

ENSMODG00000008796.4

Protein ID:

A0A5F8GGQ1

Persistent Id:

PTN000680241

Alternate Ids:

ENSMODP00000046649(Ensembl_PRO)	A0A5F8GGQ1(Synonym)
ENSMODG00000008796(Ensembl)	A0A5F8GGQ1_MONDO(UniProtKB-ID)
ENSMODT00000075016(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	MAP/MICROTUBULE AFFINITY-REGULATING KINASE (PTHR24346)
PANTHER Subfamily:	SERINE_THREONINE-PROTEIN KINASE MARK2 (PTHR24346:SF56)
PANTHER GO-slim Molecular Function:	protein serine/threonine kinase activity
PANTHER GO-slim Biological Process:	microtubule cytoskeleton organization intracellular signal transduction
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	non-receptor serine/threonine protein kinase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	magnesium ion binding, tau-protein kinase activity, ATP binding, protein serine/threonine kinase activity
GO BP Complete:	regulation of microtubule cytoskeleton organization, regulation of axonogenesis, establishment or maintenance of epithelial cell apical/basal polarity, establishment of cell polarity, positive regulation of neuron projection development, microtubule cytoskeleton organization, intracellular signal transduction
GO CC Complete:	dendrite, lateral plasma membrane, cytoplasm, membrane, microtubule bundle, actin filament, plasma membrane, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3332\|UniProtKB=Q7KZI7	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000043914.1\|UniProtKB=A0A2I3RZW8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000017093.3\|UniProtKB=A0A2I2ZL60	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000014131.4\|UniProtKB=F6TA28	Macaca mulatta	LDO
MOUSE\|MGI=MGI=99638\|UniProtKB=Q05512	Mus musculus	LDO
RAT\|RGD=150340794\|UniProtKB=A0A8J8XEH6	Rattus norvegicus	O
RAT\|RGD=150344259\|UniProtKB=A0A8I6A8U4	Rattus norvegicus	O
RAT\|RGD=41019284\|UniProtKB=A0A8I6A165	Rattus norvegicus	O
RAT\|RGD=1564409\|UniProtKB=A0A0G2K6V9	Rattus norvegicus	O
RAT\|RGD=708483\|UniProtKB=O08679	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000052622.1\|UniProtKB=A0A3Q1LS68	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000007825.6\|UniProtKB=A6QNL2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000013050.5\|UniProtKB=F1RPY5	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000040530.1\|UniProtKB=A0A3Q2I2P7	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000027819.3\|UniProtKB=A0A3Q2H4K5	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000051759.1\|UniProtKB=A0A3Q2HWT0	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000028096.2\|UniProtKB=A0A3Q2H026	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000021754.4\|UniProtKB=A0A9L0RDN8	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000014652.6\|UniProtKB=A0A2I2URJ0	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845030887.1\|UniProtKB=A0A8I3Q827	Canis lupus familiaris	LDO
ORNAN\|Ensembl=ENSOANG00000036135.1\|UniProtKB=A0A6I8NX34	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000003999.3\|UniProtKB=H9G8C3	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000012178.4\|UniProtKB=H9GIS6	Anolis carolinensis	LDO
XENLA\|Gene=mark2.S\|UniProtKB=A0A8J1N118	Xenopus laevis	LDO
XENLA\|Gene=mark2.L\|UniProtKB=A0A1L8GJT7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-876451\|UniProtKB=A0A6I8S976	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000005740.2\|UniProtKB=A0A3B3IL86	Oryzias latipes	LDO
DANRE\|Gene=mark2b\|UniProtKB=A0A8M3BAY8	Danio rerio	LDO
DANRE\|Gene=mark2a\|UniProtKB=A0A8M3B4V1	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000016257.1\|UniProtKB=W5NHE0	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000015568.1\|UniProtKB=W5NEV5	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000001763.1\|UniProtKB=W5M0Y8	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000008201.3\|UniProtKB=F6PJL4	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118411561\|UniProtKB=A0A9J7MJW1	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC100890266\|UniProtKB=A0A7M7SYA1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100889556\|UniProtKB=A0A7M7P9P4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC592325\|UniProtKB=A0A7M7HGN9	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00003916\|UniProtKB=Q9TW45	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG04756\|UniProtKB=A8WYE4	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00277629\|UniProtKB=A0A2A6BEG1	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00102456\|UniProtKB=A0A2A6BZY9	Pristionchus pacificus	LDO
PRIPA\|EnsemblGenome=WBGene00280367\|UniProtKB=A0A2A6C102	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0026064\|UniProtKB=Q9VGP9	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0026063\|UniProtKB=Q9VGQ0	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0260934\|UniProtKB=A1ZBL9	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP010341\|UniProtKB=A0A1S4H3R9	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP029469\|UniProtKB=A0A453YZQ5	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC032576\|UniProtKB=A0A139WKC9	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_313175\|UniProtKB=E9G331	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW014579\|UniProtKB=B7QKV7	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG192553\|UniProtKB=T1FU26	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG62924\|UniProtKB=T1FX78	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG84170\|UniProtKB=T1G5F9	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG71411\|UniProtKB=T1G0L1	helobdella robusta	LDO
HELRO\|EnsemblGenome=HelroG66187\|UniProtKB=T1FYI3	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG86903\|UniProtKB=T1G6J0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG83409\|UniProtKB=T1G552	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g139527\|UniProtKB=A7SZV3	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG27001\|UniProtKB=B3S0C9	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_34468\|UniProtKB=A9VBY4	Monosiga brevicollis	LDO
CANAL\|CGD=CAL0000177153\|UniProtKB=A0A1D8PRN8	Candida albicans	LDO
ASPFU\|EnsemblGenome=AFUA_1G11080\|UniProtKB=Q4WSZ7	Neosartorya fumigata	LDO
SCHJY\|EnsemblGenome=SJAG_02838\|UniProtKB=B6K1B3	Schizosaccharomyces japonicus	LDO
ASPFU\|EnsemblGenome=AFUA_1G11930\|UniProtKB=E9RDZ3	Neosartorya fumigata	O
SCHJY\|EnsemblGenome=SJAG_04469\|UniProtKB=B6K6W9	Schizosaccharomyces japonicus	O
SCHJY\|EnsemblGenome=SJAG_03602\|UniProtKB=B6K4P0	Schizosaccharomyces japonicus	O
BATDJ\|Gene_ORFName=BATDEDRAFT_10042\|UniProtKB=F4NZ62	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_073490\|UniProtKB=C4LXL3	Entamoeba histolytica	LDO
ENTH1\|Gene_ORFName=EHI_025300\|UniProtKB=A0A8U0WP54	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0280133\|UniProtKB=Q54VU4	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_151676\|UniProtKB=F0ZJH1	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0292304\|UniProtKB=Q54DF2	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_51418\|UniProtKB=F1A3P4	Dictyostelium purpureum	LDO
GIAIC\|EnsemblGenome=GL50803_9487\|UniProtKB=A8B530	Giardia intestinalis	LDO
PLAF7\|EnsemblGenome=PF3D7_1441300\|UniProtKB=Q8IL57	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00031618001\|UniProtKB=A0BS70	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00002297001\|UniProtKB=A0DGK1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00020040001\|UniProtKB=A0DTJ2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00018964001\|UniProtKB=A0DP01	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00030300001\|UniProtKB=A0BM97	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00004376001\|UniProtKB=A0BCL5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00018952001\|UniProtKB=A0DNY9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026401001\|UniProtKB=A0EFI7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00024498001\|UniProtKB=A0E900	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00024481001\|UniProtKB=A0E8Y3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00017966001\|UniProtKB=A0DKR9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028068001\|UniProtKB=A0BER8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00022278001\|UniProtKB=A0E1E2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00009964001\|UniProtKB=A0CSC5	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00025088001\|UniProtKB=A0EAN7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00029968001\|UniProtKB=A0BLB9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00014139001\|UniProtKB=A0D805	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00019068001\|UniProtKB=A0DPB9	Paramecium tetraurelia	O
PHYRM\|Gene=H3H0P0_PHYRM\|UniProtKB=H3H0P0	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_07g329850v5\|UniProtKB=A0A2K3DJR9	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_09g403850v5\|UniProtKB=A0A2K3DCM7	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g568050v5\|UniProtKB=A0A2K3CZG1	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_16g685389v5\|UniProtKB=A0A2K3CW32	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_02g076000v5\|UniProtKB=A0A2K3E058	Chlamydomonas reinhardtii	LDO
CHLRE\|EnsemblGenome=CHLRE_01g036000v5\|UniProtKB=A0A2K3E716	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_06g251050v5\|UniProtKB=A0A2K3DLY4	Chlamydomonas reinhardtii	O
HELAN\|Gene_ORFName=HanXRQr2_Chr05g0231561\|UniProtKB=A0A9K3J1W2	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C500236580\|UniProtKB=A0A9R1XB86	Lactuca sativa	O
KLENI\|Gene_ORFName=KFL_000330150\|UniProtKB=A0A1Y1HQV7	Klebsormidium nitens	O
LACSA\|Gene_ORFName=LSAT_V11C400212270\|UniProtKB=A0A9R1XHY6	Lactuca sativa	O
KLENI\|Gene_ORFName=KFL_000980330\|UniProtKB=A0A0U9HJG2	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_007820030\|UniProtKB=A0A1Y1IQA2	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_001250250\|UniProtKB=A0A1Y1I3Z9	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000970360\|UniProtKB=A0A0U9HJE6	Klebsormidium nitens	O
MUSAM\|EnsemblGenome=Ma01_g02460\|UniProtKB=A0A804HPI0	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma00_g00400\|UniProtKB=A0A804HLY2	Musa acuminata subsp. malaccensis	LDO
MUSAM\|EnsemblGenome=Ma10_g08280\|UniProtKB=A0A804KTZ1	Musa acuminata subsp. malaccensis	LDO
MAIZE\|EnsemblGenome=Zm00001eb013270\|UniProtKB=Q6RXY1	Zea mays	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0320770\|UniProtKB=A0A8I7BB45	Hordeum vulgare subsp. vulgare	O
SETIT\|EnsemblGenome=SETIT_019716mg\|UniProtKB=K3YZK6	Setaria italica	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0060110\|UniProtKB=A0A8I6X3U9	Hordeum vulgare subsp. vulgare	O
MAIZE\|EnsemblGenome=Zm00001eb293240\|UniProtKB=A0A804Q4X7	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb353700\|UniProtKB=A0A804QSJ7	Zea mays	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0286490\|UniProtKB=A0A8I6XFN7	Hordeum vulgare subsp. vulgare	LDO
SPIOL\|Gene=LOC110800356\|UniProtKB=A0A9R0J5M8	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HanXRQr2_Chr07g0308661\|UniProtKB=A0A9K3ING8	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C900467660\|UniProtKB=A0A9R1UGU9	Lactuca sativa	LDO
PHYPA\|EnsemblGenome=Pp3c3_5570\|UniProtKB=A0A7I4DGQ5	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0038s0082\|UniProtKB=A0A2R6X3U9	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0160s0010\|UniProtKB=A0A2R6W3Y3	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_008220030\|UniProtKB=A0A1Y1INE1	Klebsormidium nitens	LDO
STRCO\|Gene_OrderedLocusName=SCO4820\|UniProtKB=Q9K3K0	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO4817\|UniProtKB=Q9K3K3	Streptomyces coelicolor	O
DEIRA\|EnsemblGenome=DR_1213\|UniProtKB=Q9RV17	Deinococcus radiodurans	O
RHOBA\|EnsemblGenome=RB12694\|UniProtKB=Q7UI82	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_576\|UniProtKB=O66844	Aquifex aeolicus	O