PANTHER Gene Information

Gene Symbol(s):

Fignl2

Organism:

Mus musculus

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Gene Name:

Fidgetin-like 2

Gene ID:

MGI:3646919

Protein ID:

J3QK54

Persistent Id:

PTN001497314

Alternate Ids:

ENSMUST00000178140(Ensembl_TRS)	ENSMUSP00000137256(Ensembl_PRO)
ENSMUSG00000095440(Ensembl)	J3QK54(Synonym)
XM_006521283(refSeq)	568993097(GI)
MGI:3646919(MGI)	J3QK54_MOUSE(UniProtKB-ID)
668225(GeneID)
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PANTHER Classification

PANTHER Family:	AAA DOMAIN-CONTAINING (PTHR23074)
PANTHER Subfamily:	FIDGETIN-LIKE PROTEIN 2 (PTHR23074:SF33)
PANTHER GO-slim Molecular Function:	catalytic activity, acting on a protein ATP hydrolysis activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	non-motor microtubule binding protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ATP hydrolysis activity, microtubule severing ATPase activity
GO BP Complete:	negative regulation of axon regeneration, microtubule severing, negative regulation of wound healing, spreading of epidermal cells, negative regulation of cell migration
GO CC Complete:	cell leading edge

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=13287\|UniProtKB=A6NMB9	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000052556.1\|UniProtKB=A0A2J8KDL7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000038213.1\|UniProtKB=A0A2I2ZRM0	Gorilla gorilla gorilla	LDO
RAT\|RGD=1566321\|UniProtKB=A0A8I6AGW3	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000002673.5\|UniProtKB=F1MP95	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000062762.1\|UniProtKB=A0A8W4FLK4	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000028937.1\|UniProtKB=A0A3Q2KZE4	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000044265.1\|UniProtKB=A0A337SAX3	Felis catus	LDO
CHICK\|Ensembl=ENSGALG00010022248.1\|UniProtKB=A0A8V0ZPC0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000016922.3\|UniProtKB=G1KTA2	Anolis carolinensis	LDO
XENLA\|Gene=fignl2.S\|UniProtKB=A0A1L8H9X7	Xenopus laevis	O
XENLA\|Gene=LOC108708614\|UniProtKB=A0A8J0U8L0	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1217632\|UniProtKB=F6QRT1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000006937.2\|UniProtKB=H2LRL4	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-090313-189\|UniProtKB=E9QEA3	Danio rerio	LDO
ORYLA\|Ensembl=ENSORLG00000003424.2\|UniProtKB=H2LE86	Oryzias latipes	O
CIOIN\|Ensembl=ENSCING00000009557.3\|UniProtKB=F6U7Z2	Ciona intestinalis	O
BRAFL\|Gene=LOC118414566\|UniProtKB=A0A9J7MPQ0	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC578480\|UniProtKB=A0A7M7NV34	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00017981\|UniProtKB=O16299	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00040545\|UniProtKB=Q60QD1	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00108556\|UniProtKB=A0A2A6CRN3	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0031519\|UniProtKB=Q9VQN8	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007769\|UniProtKB=A0A1S4GW68	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC016198\|UniProtKB=D6X4S0	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_322816\|UniProtKB=E9GX18	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW020323\|UniProtKB=B7PXC9	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG94331\|UniProtKB=T1G901	helobdella robusta	O
TRIAD\|EnsemblGenome=TriadG31346\|UniProtKB=B3S8W9	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_16309\|UniProtKB=A9UXA8	Monosiga brevicollis	O
YEAST\|SGD=S000005995\|UniProtKB=P40328	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AEL244W\|UniProtKB=Q758K6	Eremothecium gossypii	O
YEAST\|SGD=S000000849\|UniProtKB=P39955	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ADL109W\|UniProtKB=Q75AN1	Eremothecium gossypii	O
CANAL\|CGD=CAL0000185972\|UniProtKB=A0A1D8PU31	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_B20834g\|UniProtKB=Q6CDV8	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_03691\|UniProtKB=C8V7L6	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_6G12560\|UniProtKB=Q4WLR8	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU02420\|UniProtKB=V5IKK6	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_14515\|UniProtKB=Q0U101	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC947.01\|UniProtKB=O43078	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_04566\|UniProtKB=B6K760	Schizosaccharomyces japonicus	O
SCHPO\|PomBase=SPAC328.04\|UniProtKB=Q9P3U2	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_01530\|UniProtKB=B6JY71	Schizosaccharomyces japonicus	O
BATDJ\|Gene_ORFName=BATDEDRAFT_12021\|UniProtKB=F4P538	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_036890\|UniProtKB=C4M9V6	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0268334\|UniProtKB=Q55GC3	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_91262\|UniProtKB=F0ZA08	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_15_0500\|UniProtKB=Q4QFD5	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.3.1440\|UniProtKB=Q57XX7	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb927.5.1870\|UniProtKB=Q57ZQ6	Trypanosoma brucei	O
GIAIC\|EnsemblGenome=GL50803_8389\|UniProtKB=A8B8X5	Giardia intestinalis	O
GIAIC\|EnsemblGenome=GL50803_10361\|UniProtKB=A8BCX5	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_498860\|UniProtKB=A2E874	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_245050\|UniProtKB=A2EMS7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_028490\|UniProtKB=A2E096	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_339190\|UniProtKB=A2FMT2	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_0407900\|UniProtKB=Q9U0K7	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00018989001\|UniProtKB=A0DP41	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00003720001\|UniProtKB=A0E6D8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00032338001\|UniProtKB=A0BU89	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000709001\|UniProtKB=A0CJN0	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00004306001\|UniProtKB=A0BCE5	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_35108\|UniProtKB=B8C5U9	Thalassiosira pseudonana	O
PHYRM\|Gene=H3G503_PHYRM\|UniProtKB=H3G503	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_12g541300v5\|UniProtKB=A0A2K3D6V7	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_01g022000v5\|UniProtKB=A0A2K3E645	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00013p00217890\|UniProtKB=W1PRU0	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_20G00360\|UniProtKB=A0A0K9PKH4	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_221G00370\|UniProtKB=A0A0K9PJB1	Zostera marina	O
MUSAM\|EnsemblGenome=Ma06_g29380\|UniProtKB=A0A804JLS8	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_021384mg\|UniProtKB=K3Z4B6	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3008G092800\|UniProtKB=A0A1B6PCH4	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb133210\|UniProtKB=A0A1D6MTY9	Zea mays	O
BRADI\|EnsemblGenome=BRADI_4g07862v3\|UniProtKB=A0A0Q3H0K4	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0449630\|UniProtKB=A0A287QST2	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS5A02G109500\|UniProtKB=A0A3B6KFK5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5D02G123800\|UniProtKB=A0A3B6MND4	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G110300\|UniProtKB=A0A3B6LIA2	Triticum aestivum	O
NELNU\|Gene=LOC104592907\|UniProtKB=A0A1U7ZQ03	Nelumbo nucifera	O
SPIOL\|Gene=LOC110783515\|UniProtKB=A0A9R0I6I7	Spinacia oleracea	O
HELAN\|Gene_ORFName=HanXRQr2_Chr07g0306731\|UniProtKB=A0A9K3IN61	Helianthus annuus	O
HELAN\|Gene_ORFName=HannXRQ_Chr07g0198241\|UniProtKB=A0A251UCX4	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C200084740\|UniProtKB=A0A9R1WE66	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C200084750\|UniProtKB=A0A9R1XX56	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C200084730\|UniProtKB=A0A9R1WAL6	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a002482mg\|UniProtKB=A0A022RY15	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_21549\|UniProtKB=A0A2G2YWZ4	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_07153\|UniProtKB=A0A2G3ACW9	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400020257\|UniProtKB=M1BT12	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc02g094100.3\|UniProtKB=A0A3Q7FEB4	Solanum lycopersicum	O
TOBAC\|Gene=LOC107832228\|UniProtKB=A0A1S4DQ27	Nicotiana tabacum	O
TOBAC\|Gene=LOC107815741\|UniProtKB=A0A1S4C6K4	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi14g01553\|UniProtKB=F6H3Y5	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_J02336\|UniProtKB=A0A059AGT6	Eucalyptus grandis	O
BRANA\|Gene_ORFName=DARMORV10_C02P53750.1\|UniProtKB=A0A078GTI9	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00056160001\|UniProtKB=A0A078H8Q8	Brassica napus	O
BRACM\|EnsemblGenome=Bra032982\|UniProtKB=M4EVZ9	Brassica campestris	O
ARATH\|TAIR=locus=2092025\|UniProtKB=F4JEX5	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107892163\|UniProtKB=A0A1U8I8T9	Gossypium hirsutum	O
GOSHI\|Gene=LOC107888805\|UniProtKB=A0A1U8HRA9	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_045256\|UniProtKB=A0A061FSJ4	Theobroma cacao	O
THECC\|EnsemblGenome=TCM_017182\|UniProtKB=A0A061ECS8	Theobroma cacao	O
POPTR\|Gene_ORFName=POPTR_001G331300\|UniProtKB=A0A3N7EKJ6	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_001G331200v3\|UniProtKB=A0A2K2C7G3	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_15G160100\|UniProtKB=A0A2C9UG76	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1889840\|UniProtKB=B9TDQ0	Ricinus communis	O
RICCO\|Gene_ORFName=RCOM_1677350\|UniProtKB=B9RBJ1	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_05G077900\|UniProtKB=K7KP02	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_19G071600\|UniProtKB=K7MX18	Glycine max	O
MEDTR\|EnsemblGenome=MTR_6g023865\|UniProtKB=A0A072U8N4	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_6g023845\|UniProtKB=A0A072U7W5	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_6g023855\|UniProtKB=A0A072U717	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_6g023875\|UniProtKB=A0A072U6S6	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr01_06530\|UniProtKB=A0A2I4HVM0	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_2G406700\|UniProtKB=A0A0A0LQU8	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_3G305500\|UniProtKB=M5WWL6	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_236550\|UniProtKB=D8TAF4	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_97809\|UniProtKB=D8RMW2	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_35516\|UniProtKB=D8RMQ4	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c4_18320\|UniProtKB=A0A2K1KP26	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0035s0108\|UniProtKB=A0A2R6X5F9	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_000380210\|UniProtKB=A0A1Y1HTC5	Klebsormidium nitens	O
NITMS\|EnsemblGenome=Nmar_1088\|UniProtKB=A9A4K6	Nitrosopumilus maritimus	O
SACS2\|EnsemblGenome=SSO0909\|UniProtKB=Q97ZJ7	Sulfolobus solfataricus	O
THEKO\|EnsemblGenome=TK1139\|UniProtKB=Q5JE76	Thermococcus kodakaraensis	O