PANTHER Gene Information   
Gene Symbol(s): Ren1
Organism: Mus musculus
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Gene Name: Renin-1
Gene ID: MGI:97898
Protein ID: P06281
Persistent Id: PTN000342898
Alternate Ids:
M32352(EMBL) 200690(GI)
AAA40044(EMBL-CDS) ENSMUSG00000070645(Ensembl)
Kidney renin(Synonym) Q543E5(AltAccession)
ENSMUSP00000092135(Ensembl_PRO) CHEMBL2615(ChEMBL)
RENI1_MOUSE(UniProtKB-ID) 19701(GeneID)
Ren1{ECO:0000303|PubMed:6370686,ECO:0000312|EMBL:CAA25391.1}(Symbol) ENSMUST00000094556(Ensembl_TRS)
3.4.23.15 {ECO:0000250|UniProtKB:P00797}(EC) NP_112469(refSeq)
MGI:97898(MGI)
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PANTHER Classification
PANTHER Family: BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED (PTHR47966)
PANTHER Subfamily: RENIN (PTHR47966:SF24)  
PANTHER GO-slim Molecular Function: aspartic-type endopeptidase activity
PANTHER GO-slim Biological Process: regulation of systemic arterial blood pressure
protein processing
peptide metabolic process
hormone metabolic process
PANTHER GO-slim Cellular Component: extracellular space
PANTHER protein class: aspartic protease
Pathway Categories: No pathway information available
GO MF Complete: aspartic-type endopeptidase activity, endopeptidase activity, peptidase activity, signaling receptor binding, insulin-like growth factor receptor binding
GO BP Complete: drinking behavior, regulation of MAPK cascade, male gonad development, response to cAMP, cell maturation, response to xenobiotic stimulus, juxtaglomerular apparatus development, regulation of blood pressure, angiotensin maturation, hormone-mediated signaling pathway, regulation of blood volume by renin-angiotensin, renin-angiotensin regulation of aldosterone production, kidney development, mesonephros development, proteolysis, response to lipopolysaccharide, cellular response to xenobiotic stimulus, response to immobilization stress, amyloid-beta metabolic process, response to cGMP
GO CC Complete: extracellular space, apical part of cell, membrane, extracellular region, intracellular anatomical structure
Reactome Pathways: Peptide hormone metabolism, Metabolism of Angiotensinogen to Angiotensins, Metabolism of proteins