PANTHER Gene Information   
Gene Symbol(s): Nr3c2
Organism: Mus musculus
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Gene Name: Mineralocorticoid receptor
Gene ID: MGI:99459
Protein ID: Q8VII8
Persistent Id: PTN000639534
Alternate Ids:
17384009(GI) CAC86375(EMBL-CDS)
MCR_MOUSE(UniProtKB-ID) Q8VII9(AltAccession)
MR(Synonym) MGI:99459(MGI)
AJ311856(EMBL) Nr3c2(Symbol)
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PANTHER Classification
PANTHER Family: KNIRPS-RELATED PROTEIN-RELATED (PTHR48092)
PANTHER Subfamily: MINERALOCORTICOID RECEPTOR (PTHR48092:SF19)  
PANTHER GO-slim Molecular Function: RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
signaling receptor activity
PANTHER GO-slim Biological Process: regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component: chromatin
nucleus
PANTHER protein class: C4 zinc finger nuclear receptor
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: zinc ion binding, histone acetyltransferase binding, identical protein binding, estrogen response element binding, double-stranded DNA binding, sequence-specific DNA binding, steroid binding, transcription coactivator binding, protein-containing complex binding, DNA-binding transcription factor activity, protein binding, nuclear receptor activity, nuclear steroid receptor activity, TBP-class protein binding, sequence-specific double-stranded DNA binding
GO BP Complete: cellular response to aldosterone, regulation of postsynaptic membrane potential, regulation of potassium:proton exchanging ATPase activity, potassium ion homeostasis, signal transduction, angiotensin-activated signaling pathway, positive regulation of non-canonical NF-kappaB signal transduction, regulation of DNA-templated transcription, intracellular sodium ion homeostasis, presynaptic modulation of chemical synaptic transmission, positive regulation of transcription by RNA polymerase II, regulation of cell population proliferation, regulation of transcription by RNA polymerase II, response to corticosterone, regulation of blood volume by renal aldosterone, locomotory behavior, nuclear receptor-mediated steroid hormone signaling pathway, nuclear receptor-mediated corticosteroid signaling pathway, renal sodium excretion
GO CC Complete: endoplasmic reticulum membrane, GABA-ergic synapse, nucleus, presynapse, cytoplasm, postsynaptic density, intracellular component, presynaptic active zone cytoplasmic component, receptor complex, glutamatergic synapse, chromatin, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Cellular responses to stimuli, SUMOylation of intracellular receptors, SUMO E3 ligases SUMOylate target proteins, HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand, Generic Transcription Pathway, Nuclear Receptor transcription pathway, Metabolism of proteins, Gene expression (Transcription), Cellular responses to stress, Post-translational protein modification, SUMOylation, RNA Polymerase II Transcription

Orthologs