PANTHER Gene Information

Gene Symbol(s):

Syt2

Organism:

Mus musculus

View Gene in Tree


Tree	Reduced Tree

Gene Name:

Synaptotagmin-2

Gene ID:

MGI:99666

Protein ID:

P46097

Persistent Id:

PTN000001856

Alternate Ids:

Q8R0E1(AltAccession)	1174546(GI)
MGI:99666(MGI)	SYT2_MOUSE(UniProtKB-ID)
AAH27019(EMBL-CDS)	XM_006529322(refSeq)
Synaptotagmin II {ECO:0000312\|MGI:MGI:99666}(Synonym)	20980(GeneID)
AF257304(EMBL)	Syt2{ECO:0000312\|MGI:MGI:99666}(Symbol)
Show All

PANTHER Classification

PANTHER Family:	SYNAPTOTAGMIN (PTHR10024)
PANTHER Subfamily:	SYNAPTOTAGMIN-2 (PTHR10024:SF223)
PANTHER GO-slim Molecular Function:	SNARE binding calcium ion binding phosphatidylserine binding clathrin binding
PANTHER GO-slim Biological Process:	synaptic vesicle exocytosis synaptic vesicle endocytosis calcium-ion regulated exocytosis
PANTHER GO-slim Cellular Component:	axon plasma membrane synaptic vesicle membrane secretory granule
PANTHER protein class:	membrane trafficking regulatory protein

Pathway Categories:

Synaptic vesicle trafficking

Synaptotagmin

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	phosphatidylserine binding, protein binding, syntaxin binding, calcium ion binding, calcium ion sensor activity, SNARE binding, inositol 1,3,4,5 tetrakisphosphate binding, calcium-dependent phospholipid binding
GO BP Complete:	vesicle-mediated transport, positive regulation of dendrite extension, calcium-dependent activation of synaptic vesicle fusion, cell differentiation, regulation of synaptic vesicle exocytosis, regulation of calcium ion-dependent exocytosis
GO CC Complete:	exocytic vesicle, chromaffin granule membrane, neuromuscular junction, synaptic vesicle membrane, dense core granule, plasma membrane, axon

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Vesicle-mediated transport, Cargo recognition for clathrin-mediated endocytosis, Clathrin-mediated endocytosis, Membrane Trafficking

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11510\|UniProtKB=Q8N9I0	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000001854.5\|UniProtKB=A0A2J8QWL9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000004495.3\|UniProtKB=G3QPB7	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000004001.4\|UniProtKB=F6XQZ0	Macaca mulatta	LDO
RAT\|RGD=3804\|UniProtKB=P29101	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000047648.2\|UniProtKB=A0A3Q1LZP6	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000010926.5\|UniProtKB=F1S5A0	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000010960.4\|UniProtKB=A0A9L0SH25	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000000454.5\|UniProtKB=A0A337S2H8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845015072.1\|UniProtKB=A0A8I3P087	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000000684.4\|UniProtKB=F6WM83	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000040777.1\|UniProtKB=A0A6I8NT59	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010026315.1\|UniProtKB=A0A8V1A869	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000003847.4\|UniProtKB=G1KCC0	Anolis carolinensis	LDO
XENLA\|Gene=LOC108709437\|UniProtKB=A0A1L8H6M9	Xenopus laevis	LDO
XENLA\|Gene=LOC108708151\|UniProtKB=A0A1L8HET0	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-981211\|UniProtKB=F7EGU7	Xenopus tropicalis	LDO
XENTR\|Gene=LOC100493529\|UniProtKB=A0A8J0R089	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000013338.2\|UniProtKB=H2MDR8	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-060503-315\|UniProtKB=F1R5C0	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000007159.2\|UniProtKB=A0A3B3H431	Oryzias latipes	LDO
DANRE\|Gene=LOC559637\|UniProtKB=A0A8M9QBF7	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000009878.1\|UniProtKB=W5MUL7	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006816.3\|UniProtKB=F6TZR8	Ciona intestinalis	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_120531\|UniProtKB=C3Z4L9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118417681\|UniProtKB=A0A9J7LAS0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118406658\|UniProtKB=A0A9J7KK38	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC752447\|UniProtKB=A0A7M7NZL4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC755798\|UniProtKB=A0A7M7G0T7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115917880\|UniProtKB=A0A7M7NYG5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115921646\|UniProtKB=A0A7M7NGD2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC373478\|UniProtKB=A0A7M7NYD5	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00004925\|UniProtKB=O16700	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00028699\|UniProtKB=A8X269	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00118488\|UniProtKB=A0A2A6C9X4	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00004922\|UniProtKB=K8FE10	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00035598\|UniProtKB=A8XLH0	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00090226\|UniProtKB=A0A2A6BQW9	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00008438\|UniProtKB=G5EDP5	Caenorhabditis elegans	O
PRIPA\|EnsemblGenome=WBGene00091526\|UniProtKB=A0A2A6CXX6	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00004923\|UniProtKB=Q965S5	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00028703\|UniProtKB=A8X273	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00118741\|UniProtKB=A0A2A6CGF4	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00004921\|UniProtKB=P34693	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00032329\|UniProtKB=A8XCL2	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00097802\|UniProtKB=A0A2A6BZB9	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0261089\|UniProtKB=C0HDP4	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP008650\|UniProtKB=A0A1S4GYU8	Anopheles gambiae	O
DROME\|FlyBase=FBgn0004242\|UniProtKB=P21521	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007942\|UniProtKB=Q7PN22	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC007227\|UniProtKB=D2A0P6	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_442623\|UniProtKB=E9FTC0	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW011463\|UniProtKB=B7Q6I0	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG170390\|UniProtKB=T1F2Z9	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG65797\|UniProtKB=T1FYC7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG163371\|UniProtKB=T1ETY8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG78642\|UniProtKB=T1G3E0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG82086\|UniProtKB=T1G4M6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG85838\|UniProtKB=T1G633	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g247877\|UniProtKB=A7SX18	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g85661\|UniProtKB=A7RKX9	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g136167\|UniProtKB=A7SX19	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g115870\|UniProtKB=A7SEZ4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g136571\|UniProtKB=A7SXC9	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g130783\|UniProtKB=A7ST77	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g136185\|UniProtKB=A7SX17	Nematostella vectensis	O
TRIAD\|Gene_ORFName=TRIADDRAFT_61791\|UniProtKB=B3SBZ4	Trichoplax adhaerens	O