PANTHER Gene Information

Gene Symbol(s):

MCM7

Organism:

Neurospora crassa

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Gene Name:

DNA replication licensing factor MCM7

Gene ID:

NCU08119

Protein ID:

Q7SD07

Persistent Id:

PTN000180082

Alternate Ids:

Q7SD07(Synonym)	Q7SD07_NEUCR(UniProtKB-ID)
3880027(GeneID)	28925623(GI)
EAA34642(EMBL-CDS)	NCU08119(Ensembl)
XP_963878(refSeq)	CM002236(EMBL)
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PANTHER Classification

PANTHER Family:	DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER (PTHR11630)
PANTHER Subfamily:	DNA REPLICATION LICENSING FACTOR MCM7 (PTHR11630:SF26)
PANTHER GO-slim Molecular Function:	single-stranded DNA binding single-stranded DNA helicase activity
PANTHER GO-slim Biological Process:	DNA unwinding involved in DNA replication DNA replication initiation double-strand break repair via break-induced replication DNA strand elongation involved in DNA replication
PANTHER GO-slim Cellular Component:	MCM complex nucleus
PANTHER protein class:	DNA metabolism protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ATP hydrolysis activity, double-stranded DNA helicase activity, helicase activity, four-way junction helicase activity, MCM complex binding, chromatin binding, forked DNA-dependent helicase activity, 3'-5' DNA helicase activity, cohesin loader activity, single-stranded DNA binding, DNA binding, DNA replication origin binding, ATP binding, DNA helicase activity, DNA clamp loader activity, ATP-dependent H2AZ histone chaperone activity, single-stranded RNA binding, ATP-dependent H3-H4 histone complex chaperone activity, single-stranded 3'-5' DNA helicase activity, 3'-5' DNA/RNA helicase activity, single-stranded DNA helicase activity, chromatin extrusion motor activity, hydrolase activity
GO BP Complete:	DNA replication initiation, nuclear DNA replication, subtelomeric heterochromatin formation, double-strand break repair via break-induced replication, DNA replication, DNA strand elongation involved in DNA replication, DNA duplex unwinding, pre-replicative complex assembly involved in nuclear cell cycle DNA replication, chromatin looping, silent mating-type cassette heterochromatin formation, DNA unwinding involved in DNA replication, premeiotic DNA replication
GO CC Complete:	chromosome, telomeric region, nucleus, nuclear pre-replicative complex, CMG complex, cytoplasm, DNA replication preinitiation complex, nuclear replication fork, replication fork protection complex, chromatin, MCM complex, MCM core complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6950\|UniProtKB=P33993	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000019472.6\|UniProtKB=H2QV16	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000002733.3\|UniProtKB=G3QJU2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000013442.4\|UniProtKB=H9FUI5	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1298398\|UniProtKB=Q61881	Mus musculus	LDO
RAT\|RGD=1303018\|UniProtKB=Q6AYN8	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000030965\|UniProtKB=Q3ZBH9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000032180.2\|UniProtKB=A0A286ZJM4	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000015149.4\|UniProtKB=F7C432	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000003562.5\|UniProtKB=M3W0J7	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845002696.1\|UniProtKB=A0A8I3MQG2	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000004229.4\|UniProtKB=F6UBM6	Monodelphis domestica	LDO
XENLA\|Gene=mcm7-a\|UniProtKB=Q91876	Xenopus laevis	O
XENLA\|Gene=mcm7-b\|UniProtKB=Q7ZXB1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5946446\|UniProtKB=Q6NX31	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000000527.2\|UniProtKB=H2L4G5	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-020419-27\|UniProtKB=Q7ZVL6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000013075.1\|UniProtKB=W5N653	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004388.3\|UniProtKB=F7AUJ3	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118427281\|UniProtKB=A0A9J7N7U8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC574771\|UniProtKB=A0A7M7HGE4	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00003159\|UniProtKB=O16297	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00040547\|UniProtKB=A8Y108	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00114518\|UniProtKB=A0A2A6CFK6	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0020633\|UniProtKB=Q9XYU0	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP005800\|UniProtKB=Q7Q6K1	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC013713\|UniProtKB=D6WK36	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_301022\|UniProtKB=E9HG94	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW023152\|UniProtKB=B7QHT6	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG96289\|UniProtKB=T1G9B2	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g237165\|UniProtKB=A7SEF9	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG19118\|UniProtKB=B3RM12	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_14950\|UniProtKB=A9UTF2	Monosiga brevicollis	LDO
YEAST\|SGD=S000000406\|UniProtKB=P38132	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_ADR041W\|UniProtKB=Q75A77	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000195352\|UniProtKB=A0A1D8PIE7	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_B18722g\|UniProtKB=Q6CE42	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_05992\|UniProtKB=Q5B0D8	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_2G10140\|UniProtKB=Q4X1F6	Neosartorya fumigata	LDO
SCLS1\|Gene_ORFName=SS1G_12751\|UniProtKB=A7F576	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_03552\|UniProtKB=Q0UXG2	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC25D12.03c\|UniProtKB=O75001	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_00884\|UniProtKB=B6JWV9	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNF01550\|UniProtKB=Q5KFJ3	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_06402\|UniProtKB=A0A0D1DNS0	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_08637\|UniProtKB=E3KGM6	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_87035\|UniProtKB=F4NY51	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_158110\|UniProtKB=C4M2D0	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0282933\|UniProtKB=Q54RU0	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_152234\|UniProtKB=F0ZKU0	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_32_2960\|UniProtKB=Q9U1E0	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.01.7810\|UniProtKB=Q381H2	Trypanosoma brucei	LDO
GIAIC\|Gene_ORFName=GL50803_0010765\|UniProtKB=A0A644F5K8	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_130190\|UniProtKB=A2DIB5	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_0705400\|UniProtKB=Q8IC16	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00038086001\|UniProtKB=A0CFS8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00014901001\|UniProtKB=A0DAC7	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_262526\|UniProtKB=B8C2X2	Thalassiosira pseudonana	LDO
PHYRM\|Gene=MCM7\|UniProtKB=H3G6K6	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_10g455850v5\|UniProtKB=A0A2K3DBH2	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00057p00030490\|UniProtKB=U5D5N4	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_41G00060\|UniProtKB=A0A0K9P2H6	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma02_g04040\|UniProtKB=A0A804HZ20	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_021342mg\|UniProtKB=K3Z474	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3008G129200\|UniProtKB=A0A1B6PDC2	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb028400\|UniProtKB=C0HFI8	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb137000\|UniProtKB=A0A1D6MXA3	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os12g0560700\|UniProtKB=Q2QNM1	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g04730v3\|UniProtKB=I1IHI9	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0443530\|UniProtKB=A0A8I7B8E8	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5B02G094600\|UniProtKB=A0A3B6LHM9	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS5A02G088400\|UniProtKB=A0A1D6A2H3	Triticum aestivum	LDO
NELNU\|Gene=LOC104605084\|UniProtKB=A0A1U8AJY8	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110777088\|UniProtKB=A0A9R0HV46	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr06g0243481\|UniProtKB=A0A251UFN3	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C700381660\|UniProtKB=A0A9R1UXM9	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a022425mg\|UniProtKB=A0A022Q035	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a002078mg\|UniProtKB=A0A022S1V0	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_02753\|UniProtKB=A0A1U8FE76	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400009040\|UniProtKB=M1AI64	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc01g079507.1\|UniProtKB=A0A3Q7EHI4	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107774668\|UniProtKB=A0A1S3YC25	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107795499\|UniProtKB=A0A1S4AAH6	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi07g00411\|UniProtKB=D7U2I1	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_H01043\|UniProtKB=A0A059AX79	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00018389001\|UniProtKB=A0A078G6F1	Brassica napus	O
BRACM\|EnsemblGenome=Bra036296\|UniProtKB=M4F5E0	Brassica campestris	O
BRACM\|EnsemblGenome=Bra000897\|UniProtKB=M4C9L8	Brassica campestris	LDO
ARATH\|TAIR=locus=2132223\|UniProtKB=P43299	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107912324\|UniProtKB=A0A1U8K0A3	Gossypium hirsutum	O
GOSHI\|Gene=LOC107924650\|UniProtKB=A0A1U8LBB4	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_004805\|UniProtKB=A0A061DR41	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g005024mg\|UniProtKB=A0A067H4R2	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_014G121000v3\|UniProtKB=B9I9J1	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_01G227600\|UniProtKB=A0A2C9WPS2	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_05G003100\|UniProtKB=A0A2C9VS28	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1347200\|UniProtKB=B9RNE8	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_19G216100\|UniProtKB=I1NBC2	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_03G219200\|UniProtKB=I1JQR6	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_7g109480\|UniProtKB=G7KST3	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr11_15910\|UniProtKB=A0A2I4GQI8	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_7G407650\|UniProtKB=A0A0A0K9I6	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_8G272000\|UniProtKB=M5VVG7	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_168902\|UniProtKB=D8R810	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_163959\|UniProtKB=D8QQX4	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c11_23510\|UniProtKB=A0A2K1JVY1	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0075s0022\|UniProtKB=A0A2R6WM15	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_004810090\|UniProtKB=A0A1Y1IJW2	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_0242\|UniProtKB=A9A310	Nitrosopumilus maritimus	O
KORCO\|EnsemblGenome=Kcr_1352\|UniProtKB=B1L6L9	Korarchaeum cryptofilum	O
SACS2\|EnsemblGenome=SSO0774\|UniProtKB=Q9UXG1	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE0901\|UniProtKB=Q8ZY88	Pyrobaculum aerophilum	O
METAC\|EnsemblGenome=MA_3829\|UniProtKB=Q8TJF6	Methanosarcina acetivorans	O
METAC\|EnsemblGenome=MA_0681\|UniProtKB=Q8TSW4	Methanosarcina acetivorans	O
METJA\|EnsemblGenome=MJ_ECL13\|UniProtKB=Q60275	Methanocaldococcus jannaschii	O
METJA\|EnsemblGenome=MJ_1489\|UniProtKB=Q58884	Methanocaldococcus jannaschii	O
METJA\|EnsemblGenome=MJ_0363\|UniProtKB=Q57809	Methanocaldococcus jannaschii	O
METJA\|EnsemblGenome=MJ_0961\|UniProtKB=Q58371	Methanocaldococcus jannaschii	O
HALSA\|EnsemblGenome=VNG_2181G\|UniProtKB=Q9HNA5	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK1361\|UniProtKB=Q5JGW1	Thermococcus kodakaraensis	O
THEKO\|EnsemblGenome=TK0096\|UniProtKB=Q5JEJ0	Thermococcus kodakaraensis	O
THEKO\|EnsemblGenome=TK1620\|UniProtKB=Q5JIT1	Thermococcus kodakaraensis	O