PANTHER Gene Information

Gene Symbol(s):

MARK1

Organism:

Ornithorhynchus anatinus

View Gene in Tree

Tree

Gene Name:

non-specific serine_threonine protein kinase

Gene ID:

ENSOANG00000001429.4

Protein ID:

A0A6I8NG83

Persistent Id:

PTN000680134

Alternate Ids:

XM_007672374(refSeq)	ENSOANT00000076782(Ensembl_TRS)
620951965(GI)	ENSOANG00000001429(Ensembl)
ENSOANP00000040238(Ensembl_PRO)	100080890(GeneID)
A0A6I8NG83_ORNAN(UniProtKB-ID)	A0A6I8NG83(Synonym)
Show All

PANTHER Classification

PANTHER Family:	MAP/MICROTUBULE AFFINITY-REGULATING KINASE (PTHR24346)
PANTHER Subfamily:	SERINE_THREONINE-PROTEIN KINASE MARK1 (PTHR24346:SF21)
PANTHER GO-slim Molecular Function:	protein serine/threonine kinase activity
PANTHER GO-slim Biological Process:	intracellular signal transduction
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	non-receptor serine/threonine protein kinase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	magnesium ion binding, ribosomal protein S6 kinase activity, DNA-dependent protein kinase activity, ATP binding, phosphatidylinositol-4,5-bisphosphate binding, histone H2AT120 kinase activity, phosphatidylserine binding, AMP-activated protein kinase activity, histone H3S57 kinase activity, histone H4S1 kinase activity, histone H3S28 kinase activity, histone H3T45 kinase activity, phosphatidic acid binding, histone H2AXS139 kinase activity, protein serine kinase activity, histone H3S10 kinase activity, histone H2BS14 kinase activity, histone H2AS1 kinase activity, protein kinase activity, eukaryotic translation initiation factor 2alpha kinase activity, protein serine/threonine kinase activity, 3-phosphoinositide-dependent protein kinase activity, tau-protein kinase activity, histone H2AS121 kinase activity, histone H3T3 kinase activity, histone H2BS36 kinase activity, Rho-dependent protein serine/threonine kinase activity, histone H3T11 kinase activity, histone H3T6 kinase activity
GO BP Complete:	regulation of dendrite development, negative regulation of gene expression, establishment of mitochondrion localization, chromatin remodeling, negative regulation of epithelial to mesenchymal transition, regulation of postsynapse assembly, positive regulation of gene expression, regulation of neuron projection development, intracellular signal transduction
GO CC Complete:	dendrite, postsynapse, cytoplasm, glutamatergic synapse, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6896\|UniProtKB=Q9P0L2	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000002000.6\|UniProtKB=A0A2I3RKZ0	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000000960.3\|UniProtKB=G3QF81	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000022288.4\|UniProtKB=F6X788	Macaca mulatta	LDO
MOUSE\|MGI=MGI=3693943\|UniProtKB=C0HKC8	Mus musculus	O
RAT\|RGD=150340942\|UniProtKB=A0A8I6ACR1	Rattus norvegicus	O
RAT\|RGD=150342998\|UniProtKB=A0A8I6GJV1	Rattus norvegicus	O
RAT\|RGD=41297741\|UniProtKB=A0A8I6A9X0	Rattus norvegicus	O
RAT\|RGD=6497368\|UniProtKB=A0A8I6ACE8	Rattus norvegicus	O
MOUSE\|MGI=MGI=2664902\|UniProtKB=Q8VHJ5	Mus musculus	LDO
RAT\|RGD=619882\|UniProtKB=O08678	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000010460.6\|UniProtKB=G5E5D4	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000010825.5\|UniProtKB=I3LBZ2	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000024459.4\|UniProtKB=A0A3Q2LKQ3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000024724.4\|UniProtKB=A0A337RWR9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845030076.1\|UniProtKB=A0A8I3S7F6	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000004622.4\|UniProtKB=A0A5F8G9U0	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010016060.1\|UniProtKB=A0A8V0Z157	Gallus gallus	LDO
CHICK\|Ensembl=ENSGALG00010017664.1\|UniProtKB=A0A1D5PF65	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000001802.4\|UniProtKB=A0A803STK5	Anolis carolinensis	LDO
XENLA\|Gene=mark1.L\|UniProtKB=A0A8J0V6D6	Xenopus laevis	O
XENLA\|Gene=mark1.S\|UniProtKB=A0A1L8G148	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-962867\|UniProtKB=A0A6I8QU93	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000001076.2\|UniProtKB=A0A3B3HYQ6	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000007134.2\|UniProtKB=A0A3B3HXI1	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-070626-2\|UniProtKB=A9JR88	Danio rerio	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_13136\|UniProtKB=F4P8J8	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_14212\|UniProtKB=F4PCH0	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_073490\|UniProtKB=C4LXL3	Entamoeba histolytica	O
ENTH1\|Gene_ORFName=EHI_025300\|UniProtKB=A0A8U0WP54	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0280133\|UniProtKB=Q54VU4	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_151676\|UniProtKB=F0ZJH1	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0292304\|UniProtKB=Q54DF2	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_51418\|UniProtKB=F1A3P4	Dictyostelium purpureum	O
GIAIC\|EnsemblGenome=GL50803_9487\|UniProtKB=A8B530	Giardia intestinalis	O
PLAF7\|EnsemblGenome=PF3D7_1441300\|UniProtKB=Q8IL57	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00031618001\|UniProtKB=A0BS70	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00002297001\|UniProtKB=A0DGK1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00020040001\|UniProtKB=A0DTJ2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00018964001\|UniProtKB=A0DP01	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00030300001\|UniProtKB=A0BM97	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00004376001\|UniProtKB=A0BCL5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00018952001\|UniProtKB=A0DNY9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026401001\|UniProtKB=A0EFI7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00024498001\|UniProtKB=A0E900	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00024481001\|UniProtKB=A0E8Y3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00017966001\|UniProtKB=A0DKR9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028068001\|UniProtKB=A0BER8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00022278001\|UniProtKB=A0E1E2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00009964001\|UniProtKB=A0CSC5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00025088001\|UniProtKB=A0EAN7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00029968001\|UniProtKB=A0BLB9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00014139001\|UniProtKB=A0D805	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00019068001\|UniProtKB=A0DPB9	Paramecium tetraurelia	O
PHYRM\|Gene=H3H0P0_PHYRM\|UniProtKB=H3H0P0	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_07g329850v5\|UniProtKB=A0A2K3DJR9	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_09g403850v5\|UniProtKB=A0A2K3DCM7	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g568050v5\|UniProtKB=A0A2K3CZG1	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_16g685389v5\|UniProtKB=A0A2K3CW32	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_02g076000v5\|UniProtKB=A0A2K3E058	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_01g036000v5\|UniProtKB=A0A2K3E716	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_06g251050v5\|UniProtKB=A0A2K3DLY4	Chlamydomonas reinhardtii	O
HELAN\|Gene_ORFName=HanXRQr2_Chr05g0231561\|UniProtKB=A0A9K3J1W2	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C500236580\|UniProtKB=A0A9R1XB86	Lactuca sativa	O
KLENI\|Gene_ORFName=KFL_000330150\|UniProtKB=A0A1Y1HQV7	Klebsormidium nitens	O
LACSA\|Gene_ORFName=LSAT_V11C400212270\|UniProtKB=A0A9R1XHY6	Lactuca sativa	O
KLENI\|Gene_ORFName=KFL_000980330\|UniProtKB=A0A0U9HJG2	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_007820030\|UniProtKB=A0A1Y1IQA2	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_001250250\|UniProtKB=A0A1Y1I3Z9	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000970360\|UniProtKB=A0A0U9HJE6	Klebsormidium nitens	O
MUSAM\|EnsemblGenome=Ma01_g02460\|UniProtKB=A0A804HPI0	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma00_g00400\|UniProtKB=A0A804HLY2	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma10_g08280\|UniProtKB=A0A804KTZ1	Musa acuminata subsp. malaccensis	O
MAIZE\|EnsemblGenome=Zm00001eb013270\|UniProtKB=Q6RXY1	Zea mays	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0320770\|UniProtKB=A0A8I7BB45	Hordeum vulgare subsp. vulgare	O
SETIT\|EnsemblGenome=SETIT_019716mg\|UniProtKB=K3YZK6	Setaria italica	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0060110\|UniProtKB=A0A8I6X3U9	Hordeum vulgare subsp. vulgare	O
MAIZE\|EnsemblGenome=Zm00001eb293240\|UniProtKB=A0A804Q4X7	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb353700\|UniProtKB=A0A804QSJ7	Zea mays	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0286490\|UniProtKB=A0A8I6XFN7	Hordeum vulgare subsp. vulgare	O
SPIOL\|Gene=LOC110800356\|UniProtKB=A0A9R0J5M8	Spinacia oleracea	O
HELAN\|Gene_ORFName=HanXRQr2_Chr07g0308661\|UniProtKB=A0A9K3ING8	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C900467660\|UniProtKB=A0A9R1UGU9	Lactuca sativa	O
PHYPA\|EnsemblGenome=Pp3c3_5570\|UniProtKB=A0A7I4DGQ5	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0038s0082\|UniProtKB=A0A2R6X3U9	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0160s0010\|UniProtKB=A0A2R6W3Y3	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_008220030\|UniProtKB=A0A1Y1INE1	Klebsormidium nitens	O
STRCO\|Gene_OrderedLocusName=SCO4820\|UniProtKB=Q9K3K0	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO4817\|UniProtKB=Q9K3K3	Streptomyces coelicolor	O
DEIRA\|EnsemblGenome=DR_1213\|UniProtKB=Q9RV17	Deinococcus radiodurans	O
RHOBA\|EnsemblGenome=RB12694\|UniProtKB=Q7UI82	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_576\|UniProtKB=O66844	Aquifex aeolicus	O