PANTHER Gene Information

Gene Symbol(s):

GJA1

Organism:

Ornithorhynchus anatinus

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Gene Name:

Gap junction protein

Gene ID:

ENSOANG00000003395.2

Protein ID:

F6TH76

Persistent Id:

PTN000240410

Alternate Ids:

ENSOANG00000003395(Ensembl)	ENSOANT00000005389(Ensembl_TRS)
F6TH76_ORNAN(UniProtKB-ID)	ENSOANP00000005388(Ensembl_PRO)
F6TH76(Synonym)
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PANTHER Classification

PANTHER Family:	CONNEXIN (PTHR11984)
PANTHER Subfamily:	GAP JUNCTION ALPHA-1 PROTEIN (PTHR11984:SF33)
PANTHER GO-slim Molecular Function:	wide pore channel activity
PANTHER GO-slim Biological Process:	heart development cell-cell signaling
PANTHER GO-slim Cellular Component:	plasma membrane protein complex cell-cell junction
PANTHER protein class:	gap junction

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	tubulin binding, transmembrane transporter activity, gap junction channel activity involved in cell communication by electrical coupling, gap junction hemi-channel activity, monoatomic ion transmembrane transporter activity, gap junction channel activity, beta-catenin binding
GO BP Complete:	positive regulation of morphogenesis of an epithelium, positive regulation of mesodermal cell differentiation, signal transduction, negative regulation of trophoblast cell migration, monoatomic ion transmembrane transport, cell-cell signaling, protein localization, establishment of mitotic spindle orientation, heart development, positive regulation of vascular associated smooth muscle cell proliferation, positive regulation of gene expression, positive regulation of stem cell proliferation, cell communication by electrical coupling, negative regulation of gonadotropin secretion
GO CC Complete:	gap junction, cell-cell contact zone, tight junction, connexin complex, cytoplasm, intracellular membrane-bounded organelle, mitochondrion, intercalated disc, cell junction, plasma membrane, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=4274\|UniProtKB=P17302	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000051898.1\|UniProtKB=A0A2I3RQ65	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010526.3\|UniProtKB=G3R4Q6	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000005225.4\|UniProtKB=F7C314	Macaca mulatta	LDO
MOUSE\|MGI=MGI=95717\|UniProtKB=Q6S5G4	Mus musculus	O
RAT\|RGD=2693\|UniProtKB=P28233	Rattus norvegicus	O
MOUSE\|MGI=MGI=95713\|UniProtKB=P23242	Mus musculus	LDO
RAT\|RGD=2690\|UniProtKB=P08050	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000001835\|UniProtKB=P18246	Bos taurus	LDO
PIG\|Gene=GJA1\|UniProtKB=Q29101	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000004241.5\|UniProtKB=F1SF43	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000005525.4\|UniProtKB=F6SK35	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000026145.4\|UniProtKB=M3WS82	Felis catus	O
FELCA\|Ensembl=ENSFCAG00000014657.5\|UniProtKB=M3X8Y2	Felis catus	LDO
CANLF\|Gene=GJA1\|UniProtKB=Q6S9C0	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845025606.1\|UniProtKB=A0A8I3PLU2	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845009132.1\|UniProtKB=A0A654IEC4	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000017758.3\|UniProtKB=F7E4P6	Monodelphis domestica	LDO
CHICK\|Gene=GJA1\|UniProtKB=P14154	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010012939.1\|UniProtKB=F1N9K3	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000007625.2\|UniProtKB=G1KZB2	Anolis carolinensis	LDO
XENLA\|Gene=gja1.S\|UniProtKB=A0A1L8G2N0	Xenopus laevis	O
XENLA\|Gene=gja1\|UniProtKB=P16863	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-876602\|UniProtKB=F6RLQ1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000015485.3\|UniProtKB=H2ML15	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050616-10\|UniProtKB=E7FBZ4	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-991105-4\|UniProtKB=O57474	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000017880.1\|UniProtKB=W5NMX4	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000007798.3\|UniProtKB=F6WH66	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000015377.2\|UniProtKB=F6WH30	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000018515.1\|UniProtKB=F7AX69	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000009598.3\|UniProtKB=F7AWX4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000019383.1\|UniProtKB=F6S9Q0	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000025022.1\|UniProtKB=H2XJX2	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000022678.1\|UniProtKB=H2Y3H1	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000018952.1\|UniProtKB=H2XKC5	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000020493.1\|UniProtKB=H2Y0D6	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000002449.3\|UniProtKB=F6QCF4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000023359.1\|UniProtKB=H2XQL4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000013649.2\|UniProtKB=F6UBJ9	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000022111.1\|UniProtKB=H2XK19	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000013396.2\|UniProtKB=F6PZH8	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000018050.1\|UniProtKB=H2Y245	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000008747.3\|UniProtKB=F6T0Z3	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000014820.2\|UniProtKB=F6S9P0	Ciona intestinalis	O