PANTHER Gene Information

Gene Symbol(s):

OTC

Organism:

Ornithorhynchus anatinus

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Gene Name:

Ornithine transcarbamylase, mitochondrial

Gene ID:

ENSOANG00000007118.3

Protein ID:

A0A6I8PCR4

Persistent Id:

PTN000150448

Alternate Ids:

100082811(GeneID)	A0A6I8PCR4(Synonym)
ENSOANG00000007118(Ensembl)	XP_007665449(refSeq)
620961188(GI)	ENSOANP00000052353(Ensembl_PRO)
A0A6I8PCR4_ORNAN(UniProtKB-ID)	ENSOANT00000056782(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL (PTHR45753)
PANTHER Subfamily:	ORNITHINE TRANSCARBAMYLASE, MITOCHONDRIAL (PTHR45753:SF3)
PANTHER GO-slim Molecular Function:	transferase activity, transferring one-carbon groups
PANTHER GO-slim Biological Process:	L-amino acid biosynthetic process arginine metabolic process proteinogenic amino acid biosynthetic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	transferase

Pathway Categories:

Arginine biosynthesis

Ornithine carbamoyl transferase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	amino acid binding, transferase activity, ornithine carbamoyltransferase activity, carboxyl- or carbamoyltransferase activity
GO BP Complete:	L-arginine biosynthetic process, ornithine catabolic process, citrulline biosynthetic process, urea cycle, ornithine metabolic process, arginine biosynthetic process via ornithine, amino acid metabolic process, ammonium homeostasis
GO CC Complete:	mitochondrion

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=8512\|UniProtKB=P00480	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000051070.1\|UniProtKB=A0A2I3TF75	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000021799.3\|UniProtKB=H2QYG7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000011703.3\|UniProtKB=G3R7S1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000013493.4\|UniProtKB=F6ZKS9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97448\|UniProtKB=P11725	Mus musculus	LDO
RAT\|RGD=3236\|UniProtKB=P00481	Rattus norvegicus	LDO
BOVIN\|Gene=OTC\|UniProtKB=Q9N1U7	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000001488.4\|UniProtKB=F1MNG5	Bos taurus	LDO
PIG\|Gene=OTC\|UniProtKB=O19072	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000012236.6\|UniProtKB=A0A480E1W6	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000022838.4\|UniProtKB=F6UW24	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000010876.6\|UniProtKB=M3WE39	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845025700.1\|UniProtKB=A0A8I3S5H5	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000021104.3\|UniProtKB=F6UHY3	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010002770.1\|UniProtKB=A0A8V0XEC2	Gallus gallus	LDO
CHICK\|Ensembl=ENSGALG00015003941\|UniProtKB=Q9YHY9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000014619.3\|UniProtKB=G1KQ60	Anolis carolinensis	LDO
XENLA\|Gene=otc.S\|UniProtKB=A0A8J1MB06	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-982300\|UniProtKB=Q6DJ41	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000009056.2\|UniProtKB=H2LYY6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-070912-422\|UniProtKB=E9QHD9	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000007928.1\|UniProtKB=W5MML8	lepisosteus oculatus	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_287613\|UniProtKB=C3Z6N9	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC588878\|UniProtKB=A0A7M7HFR5	Strongylocentrotus purpuratus	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g182282\|UniProtKB=A7RV06	Nematostella vectensis	LDO
YEAST\|SGD=S000003624\|UniProtKB=P05150	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFR098W\|UniProtKB=Q754H4	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000176534\|UniProtKB=Q5ABU0	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_D14894g\|UniProtKB=Q6C924	Yarrowia lipolytica	LDO
EMENI\|Gene_ORFName=AN4409\|UniProtKB=P11803	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_4G07190\|UniProtKB=Q4WNW5	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU01667\|UniProtKB=Q1K5I2	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_10630\|UniProtKB=A7EZ64	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_05206\|UniProtKB=Q0USQ8	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC4G9.10\|UniProtKB=P31317	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_00635\|UniProtKB=B6JW65	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNC04300\|UniProtKB=Q5KK45	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_03537\|UniProtKB=A0A0D1DW09	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_12127\|UniProtKB=E3KPE6	Puccinia graminis	LDO
GIAIC\|EnsemblGenome=GL50803_10311\|UniProtKB=E2RTT6	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_041310\|UniProtKB=A2G3U5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_038530\|UniProtKB=A2DY09	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_368740\|UniProtKB=A2EUY0	Trichomonas vaginalis	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_997\|UniProtKB=B8BT16	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3HCG4_PHYRM\|UniProtKB=H3HCG4	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_12g489700v5\|UniProtKB=A8ILJ9	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00011p00222000\|UniProtKB=W1NGS5	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_56G00760\|UniProtKB=A0A0K9NY32	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma06_g10580\|UniProtKB=A0A804JEU1	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_017196mg\|UniProtKB=K3YSF2	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G268100\|UniProtKB=C5Y0C0	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb188330\|UniProtKB=C4IZ94	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb001310\|UniProtKB=A0A804PNG1	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb255250\|UniProtKB=A0A804PPP6	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb126200\|UniProtKB=A0A804N0U8	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb216710\|UniProtKB=A0A804P8V2	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb403320\|UniProtKB=A0A804UKL8	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb252020\|UniProtKB=A0A1D6HHJ4	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os02g0704800\|UniProtKB=Q6YVI0	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g52727v3\|UniProtKB=I1ID02	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0607460\|UniProtKB=F2EEY9	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6B02G299700\|UniProtKB=A0A3B6PQN7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G252300\|UniProtKB=A0A3B6QH04	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G272200\|UniProtKB=A0A3B6NR27	Triticum aestivum	LDO
NELNU\|Gene=LOC104595651\|UniProtKB=A0A1U7ZZT9	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110789105\|UniProtKB=A0A9R0IHZ9	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HanXRQr2_Chr07g0285601\|UniProtKB=A0A9K3NF37	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C600304330\|UniProtKB=A0A9R1X6B4	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a008393mg\|UniProtKB=A0A022R3E7	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_13290\|UniProtKB=A0A1U8GBM0	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400003741\|UniProtKB=M0ZWK1	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc04g080610.3\|UniProtKB=K4BVE0	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107819553\|UniProtKB=A0A1S4CJ12	Nicotiana tabacum	O
TOBAC\|Gene=LOC107822172\|UniProtKB=A0A1S4CST9	Nicotiana tabacum	LDO
CAPAN\|EnsemblGenome=T459_16731\|UniProtKB=A0A2G2Z9N5	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_30989\|UniProtKB=A0A2G2YA09	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400015463\|UniProtKB=M1B932	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc12g089210.2\|UniProtKB=A0A3Q7JD34	Solanum lycopersicum	O
TOBAC\|Gene=LOC107799727\|UniProtKB=A0A1S4APF3	Nicotiana tabacum	O
TOBAC\|Gene=LOC107786954\|UniProtKB=A0A1S3ZHV9	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi18g00986\|UniProtKB=E0CQF4	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_F01880\|UniProtKB=A0A059BQQ2	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00063737001\|UniProtKB=A0A078HH90	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra003758\|UniProtKB=A0A397YSN9	Brassica campestris	LDO
ARATH\|TAIR=locus=2018467\|UniProtKB=O50039	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107905438\|UniProtKB=A0A1U8JBA0	Gossypium hirsutum	O
GOSHI\|Gene=LOC107943527\|UniProtKB=A0A1U8N4J3	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_034077\|UniProtKB=A0A061FJZ0	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g024871mg\|UniProtKB=A0A067HA10	Citrus sinensis	LDO
POPTR\|Gene_ORFName=POPTR_005G229400\|UniProtKB=A0A3N7F6U3	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_05G157200\|UniProtKB=A0A2C9VY17	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1595060\|UniProtKB=B9R7X3	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_04G030500\|UniProtKB=K7KHU1	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_06G030600\|UniProtKB=A0A368UI50	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g022420\|UniProtKB=A0A072VEY9	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_3g112050\|UniProtKB=A0A072V483	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr11_21080\|UniProtKB=A0A2I4ENX0	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G859690\|UniProtKB=A0A0A0LGM8	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G376500\|UniProtKB=M5XE79	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_158392\|UniProtKB=D8SUH0	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_184194\|UniProtKB=D8SZY7	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c9_2740\|UniProtKB=A0A7I4EKS7	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c9_2745\|UniProtKB=A0A2K1K1Q1	Physcomitrella patens	LDO
PHYPA\|EnsemblGenome=Pp3c15_7070\|UniProtKB=A0A7I4B1K1	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0003s0042\|UniProtKB=A0A2R6XSQ1	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001100160\|UniProtKB=A0A1Y1HXA5	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_0397\|UniProtKB=A9A594	Nitrosopumilus maritimus	LDO
KORCO\|EnsemblGenome=Kcr_1331\|UniProtKB=B1L6J8	Korarchaeum cryptofilum	O
KORCO\|EnsemblGenome=Kcr_1251\|UniProtKB=B1L6B8	Korarchaeum cryptofilum	O
KORCO\|EnsemblGenome=Kcr_0501\|UniProtKB=B1L475	Korarchaeum cryptofilum	LDO
SACS2\|EnsemblGenome=SSO0871\|UniProtKB=Q97ZM1	Sulfolobus solfataricus	LDO
PYRAE\|EnsemblGenome=PAE1985\|UniProtKB=Q8ZW40	Pyrobaculum aerophilum	LDO
METAC\|EnsemblGenome=MA_3310\|UniProtKB=Q8TKT5	Methanosarcina acetivorans	LDO
METJA\|EnsemblGenome=MJ_0881\|UniProtKB=Q58291	Methanocaldococcus jannaschii	LDO
HALSA\|EnsemblGenome=VNG_6315G\|UniProtKB=Q48296	Halobacterium salinarum	LDO
THEKO\|EnsemblGenome=TK0871\|UniProtKB=Q5JI16	Thermococcus kodakaraensis	LDO
STRCO\|Gene_OrderedLocusName=SCO5976\|UniProtKB=Q93JF1	Streptomyces coelicolor	O
CLOBH\|Gene_OrderedLocusName=CBO2593\|UniProtKB=A5I524	Clostridium botulinum	O
STRR6\|EnsemblGenome=spr1957\|UniProtKB=P65608	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_02968\|UniProtKB=Q2FUX8	Staphylococcus aureus	O
BACCR\|EnsemblGenome=BC_0407\|UniProtKB=Q81II0	Bacillus cereus	O
STAA8\|EnsemblGenome=SAOUHSC_01128\|UniProtKB=Q2FZB0	Staphylococcus aureus	O
THEMA\|EnsemblGenome=TM_1097\|UniProtKB=P96108	Thermotoga maritima	O
NEIMB\|EnsemblGenome=NMB1573\|UniProtKB=P0DH57	Neisseria meningitidis serogroup b	O
HAEIN\|EnsemblGenome=HI_0596\|UniProtKB=P44770	Haemophilus influenzae	O
VIBCH\|EnsemblGenome=VC_2508\|UniProtKB=Q9KP68	Vibrio cholerae	O
PSEAE\|EnsemblGenome=PA5172\|UniProtKB=P08308	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM4469\|UniProtKB=Q08016	Salmonella typhimurium	O
YERPE\|EnsemblGenome=YP_0638\|UniProtKB=Q8ZBG8	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE76057\|UniProtKB=P06960	Escherichia coli	O
ECOLI\|EnsemblGenome=BAE78251\|UniProtKB=P04391	Escherichia coli	O
SALTY\|EnsemblGenome=STM4465\|UniProtKB=Q8ZK35	Salmonella typhimurium	O
MYCTU\|Gene_OrderedLocusName=Rv1656\|UniProtKB=P9WIT9	Mycobacterium tuberculosis	LDO
CLOBH\|Gene_OrderedLocusName=CBO2885\|UniProtKB=A5I5W9	Clostridium botulinum	LDO
LISMO\|EnsemblGenome=CAC98251\|UniProtKB=Q8YAS7	Listeria monocytogenes	O
LISMO\|EnsemblGenome=CAC99665\|UniProtKB=Q8Y6U5	Listeria monocytogenes	LDO
BACSU\|EnsemblGenome=BSU_11250\|UniProtKB=P18186	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_4126\|UniProtKB=Q818W3	Bacillus cereus	LDO
DEIRA\|EnsemblGenome=DR_0080\|UniProtKB=Q9RY70	Deinococcus radiodurans	LDO
GLOVI\|EnsemblGenome=BAC91042\|UniProtKB=Q7NGR7	Gloeobacter violaceus	LDO
SYNY3\|EnsemblGenome=BAA10847\|UniProtKB=Q55497	Synechocystis	LDO
LEPIN\|EnsemblGenome=LA_2840\|UniProtKB=Q8F2D1	Leptospira interrogans	LDO
BACTN\|EnsemblGenome=BT_3717\|UniProtKB=Q8A1E9	Bacteroides thetaiotaomicron	LDO
RHOBA\|EnsemblGenome=RB5986\|UniProtKB=Q7UQZ6	Rhodopirellula baltica	LDO
AQUAE\|EnsemblGenome=aq_1711\|UniProtKB=O67607	Aquifex aeolicus	LDO
THEYD\|EnsemblGenome=THEYE_A0670\|UniProtKB=B5YJU7	Thermodesulfovibrio yellowstonii	LDO
GEOSL\|EnsemblGenome=GSU0152\|UniProtKB=Q74GU2	Geobacter sulfurreducens	LDO
BRADU\|EnsemblGenome=BAC46364\|UniProtKB=Q89VE8	Bradyrhizobium diazoefficiens	LDO
SHEON\|Gene_OrderedLocusName=SO_0277\|UniProtKB=Q8EK29	Shewanella oneidensis	LDO
XANCP\|EnsemblGenome=XCC2249\|UniProtKB=Q8P8J2	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA3537\|UniProtKB=P11724	Pseudomonas aeruginosa	LDO
ECOLI\|EnsemblGenome=BAE76936\|UniProtKB=Q46803	Escherichia coli	LDO