PANTHER Gene Information

Gene Symbol(s):

GRHPR

Organism:

Ornithorhynchus anatinus

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Gene Name:

Glyoxylate and hydroxypyruvate reductase

Gene ID:

ENSOANG00000048056.1

Protein ID:

A0A6I8NY03

Persistent Id:

PTN008314099

Alternate Ids:

ENSOANG00000048056(Ensembl)	A0A6I8NY03_ORNAN(UniProtKB-ID)
ENSOANT00000075814(Ensembl_TRS)	A0A6I8NY03(Synonym)
ENSOANP00000045288(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	2-HYDROXYACID DEHYDROGENASE-RELATED (PTHR10996)
PANTHER Subfamily:	GLYOXYLATE REDUCTASE_HYDROXYPYRUVATE REDUCTASE (PTHR10996:SF137)
PANTHER GO-slim Molecular Function:	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	cytosol
PANTHER protein class:	dehydrogenase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	protein homodimerization activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, oxidoreductase activity, NAD binding, hydroxypyruvate reductase [NAD(P)H] activity, NADPH binding, hydroxypyruvate reductase (NADH) activity, glyoxylate reductase (NADPH) activity
GO BP Complete:	glyoxylate metabolic process
GO CC Complete:	catalytic complex, cytoplasm, cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=4570\|UniProtKB=Q9UBQ7	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000020940.6\|UniProtKB=K7DM95	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000003710.3\|UniProtKB=G3QMB0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000045930.2\|UniProtKB=H9G201	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1923488\|UniProtKB=Q91Z53	Mus musculus	LDO
RAT\|RGD=1308851\|UniProtKB=A0A8J8XIM5	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000019299.6\|UniProtKB=A0A3Q1NGN7	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000005349.5\|UniProtKB=F1ST73	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000008981.4\|UniProtKB=A0A3Q2GSF0	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000013079.5\|UniProtKB=M3WI68	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845013630.1\|UniProtKB=A0A8I3NSV0	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000002862.4\|UniProtKB=A0A5F8GK27	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010001179.1\|UniProtKB=A0A8V0X9T4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000011898.3\|UniProtKB=H9GIA6	Anolis carolinensis	LDO
XENLA\|Gene=grhpr.2.L\|UniProtKB=Q498I1	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5815683\|UniProtKB=Q66KM4	Xenopus tropicalis	O
XENLA\|Gene=grhpr.1.L\|UniProtKB=Q6NTU8	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-953408\|UniProtKB=A0A8J0PML4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000004496.2\|UniProtKB=H2LI27	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040724-230\|UniProtKB=Q504F9	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000012851.1\|UniProtKB=W5N5A9	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000014190.2\|UniProtKB=F7A7A0	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118412687\|UniProtKB=A0A9J7MLG6	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC588349\|UniProtKB=A0A7M7TGZ1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115921758\|UniProtKB=A0A7M7NF09	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105438914\|UniProtKB=A0A7M7NF18	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0051673\|UniProtKB=Q9VII9	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0051674\|UniProtKB=Q8INU6	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0032889\|UniProtKB=Q8SZU0	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP009611\|UniProtKB=A0A1S4H2D7	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP009612\|UniProtKB=Q7PM25	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP009610\|UniProtKB=Q7PLZ4	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC006532\|UniProtKB=D6WXF3	Tribolium castaneum	O
DROME\|FlyBase=FBgn0037370\|UniProtKB=Q8I725	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP013478\|UniProtKB=F5HMM8	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC005371\|UniProtKB=D6WUR6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_207744\|UniProtKB=E9G0S0	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW019963\|UniProtKB=B7PV15	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW005870\|UniProtKB=B7PM49	Ixodes scapularis	LDO
IXOSC\|EnsemblGenome=ISCW022039\|UniProtKB=B7QFP3	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW019193\|UniProtKB=B7PPV0	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG187296\|UniProtKB=T1FP85	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g185114\|UniProtKB=A7S382	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g159915\|UniProtKB=A7RL06	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG18802\|UniProtKB=B3RK75	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG63420\|UniProtKB=B3SAF7	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG19940\|UniProtKB=B3RK84	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_19417\|UniProtKB=A9UR17	Monosiga brevicollis	LDO
PHANO\|EnsemblGenome=SNOG_08878\|UniProtKB=Q0UH86	Phaeosphaeria nodorum	LDO
CRYNJ\|EnsemblGenome=CNC02760\|UniProtKB=Q5KKJ8	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_05037\|UniProtKB=A0A0D1DXC3	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_06191\|UniProtKB=A0A0D1DP31	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_04061\|UniProtKB=A0A0D1DZR4	Ustilago maydis	LDO
DICDI\|dictyBase=DDB_G0292104\|UniProtKB=Q54DP1	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_147384\|UniProtKB=F0Z8D3	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_52429\|UniProtKB=F0Z8B1	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_44248\|UniProtKB=F1A5T1	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_147361\|UniProtKB=F0Z8B2	Dictyostelium purpureum	O
TRIV3\|Gene_ORFName=TVAG_047210\|UniProtKB=A2FHI8	Trichomonas vaginalis	O
PHYRM\|Gene=H3GAI8_PHYRM\|UniProtKB=H3GAI8	Phytophthora ramorum	O
PHYRM\|Gene=H3G4Z8_PHYRM\|UniProtKB=H3G4Z8	Phytophthora ramorum	O
PHYRM\|Gene=H3GAI7_PHYRM\|UniProtKB=H3GAI7	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_06g295450v5\|UniProtKB=A8IPI7	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00152p00085890\|UniProtKB=W1PLF0	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_1G03130\|UniProtKB=A0A0K9PQ30	Zostera marina	O
MUSAM\|EnsemblGenome=Ma05_g21330\|UniProtKB=A0A804J6X6	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_017480mg\|UniProtKB=K3YT85	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3004G001300\|UniProtKB=A0A194YLZ3	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb229250\|UniProtKB=A0A804PE80	Zea mays	O
ORYSJ\|EnsemblGenome=Os02g0101500\|UniProtKB=Q6YU90	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g00330v3\|UniProtKB=A0A0Q3J335	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0538240\|UniProtKB=F2D8L5	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS6A02G000400\|UniProtKB=A0A3B6NGZ5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6B02G004400\|UniProtKB=A0A341WSR4	Triticum aestivum	O
NELNU\|Gene=LOC104603640\|UniProtKB=A0A1U8ASF7	Nelumbo nucifera	O
SPIOL\|Gene=LOC110791537\|UniProtKB=A0A9R0JYM8	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr17g0794251\|UniProtKB=A0A251RND2	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C300120290\|UniProtKB=A0A9R1W2A7	Lactuca sativa	O
CAPAN\|EnsemblGenome=T459_32433\|UniProtKB=A0A2G2Y1W6	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_16888\|UniProtKB=A0A2G2Z9Z9	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_18953\|UniProtKB=A0A2G2Z0K8	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_14966\|UniProtKB=A0A2G2ZJ49	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_32155\|UniProtKB=A0A2G2Y2U0	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400006186\|UniProtKB=M1A6N6	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc01g111630.3\|UniProtKB=A0A3Q7EUQ6	Solanum lycopersicum	O
TOBAC\|Gene=LOC107765918\|UniProtKB=A0A1S3XJF2	Nicotiana tabacum	O
TOBAC\|Gene=LOC107805344\|UniProtKB=A0A1S4B7M2	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi03g00154\|UniProtKB=D7U543	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_I01423\|UniProtKB=A0A059ANX4	Eucalyptus grandis	O
BRANA\|Gene_ORFName=GSBRNA2T00124391001\|UniProtKB=A0A078EZ90	Brassica napus	O
BRACM\|EnsemblGenome=Bra004275\|UniProtKB=M4CJ91	Brassica campestris	O
BRACM\|EnsemblGenome=Bra004055\|UniProtKB=M4CIM1	Brassica campestris	O
ARATH\|TAIR=locus=2200231\|UniProtKB=Q9C9W5	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107921219\|UniProtKB=A0A1U8KVZ3	Gossypium hirsutum	O
GOSHI\|Gene=LOC107947132\|UniProtKB=A0A1U8NDT3	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_006612\|UniProtKB=A0A061E001	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g015895mg\|UniProtKB=A0A067FXZ6	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_004G175800v3\|UniProtKB=A0A2K2AW94	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_04G076300\|UniProtKB=A0A2C9W0M5	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1112510\|UniProtKB=B9T0F2	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_20G107800\|UniProtKB=Q84L66	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_10G281400\|UniProtKB=B0M1A3	Glycine max	O
MEDTR\|EnsemblGenome=MTR_1g112510\|UniProtKB=A0A072VRS6	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr13_09150\|UniProtKB=A0A2I4EWU8	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_7G012940\|UniProtKB=A0A0A0K5Z2	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_8G166000\|UniProtKB=A0A251MYV6	Prunus persica	O
PRUPE\|EnsemblGenome=PRUPE_7G264000\|UniProtKB=M5W8G7	Prunus persica	O
PHYPA\|EnsemblGenome=Pp3c18_12500\|UniProtKB=A9RE03	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c19_20080\|UniProtKB=A9U188	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0015s0044\|UniProtKB=A0A2R6XGJ7	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_001860030\|UniProtKB=A0A1Y1I6K8	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_001580030\|UniProtKB=A0A1Y1I2N3	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000030590\|UniProtKB=A0A1Y1HIT3	Klebsormidium nitens	O
SACS2\|EnsemblGenome=SSO3187\|UniProtKB=Q97U35	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE1175\|UniProtKB=Q8ZXP5	Pyrobaculum aerophilum	O
STRCO\|Gene_OrderedLocusName=SCO0348\|UniProtKB=Q9RJW2	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO7119\|UniProtKB=Q9FC67	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO0663\|UniProtKB=Q9RJA1	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO5510\|UniProtKB=Q9Z569	Streptomyces coelicolor	O
DEIRA\|EnsemblGenome=DR_1701\|UniProtKB=Q9RTQ5	Deinococcus radiodurans	O
CHLAA\|EnsemblGenome=Caur_0825\|UniProtKB=A9WGW6	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO2824\|UniProtKB=Q93J73	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO3478\|UniProtKB=Q9RKF9	Streptomyces coelicolor	O
CLOBH\|Gene_OrderedLocusName=CBO3593\|UniProtKB=A5I7W7	Clostridium botulinum	O
STAA8\|EnsemblGenome=SAOUHSC_01998\|UniProtKB=Q2G281	Staphylococcus aureus	O
STAA8\|EnsemblGenome=SAOUHSC_00866\|UniProtKB=Q2FZW9	Staphylococcus aureus	O
BACSU\|EnsemblGenome=BSU_34680\|UniProtKB=O32264	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_4903\|UniProtKB=Q816F6	Bacillus cereus	O
GLOVI\|Gene=Q7NEV2_GLOVI\|UniProtKB=Q7NEV2	Gloeobacter violaceus	O
SYNY3\|Gene=P73990_SYNY3\|UniProtKB=P73990	Synechocystis	O
LEPIN\|EnsemblGenome=LA_1629\|UniProtKB=Q8F5N8	Leptospira interrogans	O
RHOBA\|EnsemblGenome=RB10004\|UniProtKB=Q7UKR1	Rhodopirellula baltica	O
DICTD\|EnsemblGenome=Dtur_1692\|UniProtKB=B8E390	Dictyoglomus turgidum	O
BRADU\|Gene=Q89EL0_BRADU\|UniProtKB=Q89EL0	Bradyrhizobium diazoefficiens	O
BRADU\|Gene=Q89WC5_BRADU\|UniProtKB=Q89WC5	Bradyrhizobium diazoefficiens	O
XANCP\|EnsemblGenome=XCC2550\|UniProtKB=Q8P7R1	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA3896\|UniProtKB=Q9HXB7	Pseudomonas aeruginosa	O
PSEAE\|EnsemblGenome=PA2263\|UniProtKB=Q9I1L0	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM3646\|UniProtKB=Q8ZLA1	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO2536\|UniProtKB=A0A3N4B3L9	Yersinia pestis	O
YERPE\|Gene_OrderedLocusName=YPO1288\|UniProtKB=A0A3N4B378	Yersinia pestis	O
YERPE\|EnsemblGenome=YP_3988\|UniProtKB=Q0W9V5	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE77742\|UniProtKB=P37666	Escherichia coli	O