PANTHER Gene Information

Gene Symbol(s):

SYT12

Organism:

Pan troglodytes

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Gene Name:

Synaptotagmin 12

Gene ID:

ENSPTRG00000003943.6

Protein ID:

A0A2J8QB49

Persistent Id:

PTN000001636

Alternate Ids:

XP_016776822(refSeq)	AC193198(EMBL)
ENSPTRG00000003943(Ensembl)	1034089800(GI)
ENSPTRT00000007362(Ensembl_TRS)	A0A2J8QB49(Synonym)
466682(GeneID)	ENSPTRP00000006789(Ensembl_PRO)
A0A2J8QB49_PANTR(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	SYNAPTOTAGMIN (PTHR10024)
PANTHER Subfamily:	SYNAPTOTAGMIN-12 (PTHR10024:SF252)
PANTHER GO-slim Molecular Function:	SNARE binding calcium ion binding phosphatidylserine binding clathrin binding
PANTHER GO-slim Biological Process:	synaptic vesicle exocytosis synaptic vesicle endocytosis calcium-ion regulated exocytosis
PANTHER GO-slim Cellular Component:	plasma membrane exocytic vesicle
PANTHER protein class:	membrane trafficking regulatory protein

Pathway Categories:

Synaptic vesicle trafficking

Synaptotagmin

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	calcium ion sensor activity, SNARE binding, calcium-dependent phospholipid binding
GO BP Complete:	vesicle-mediated transport, long-term synaptic potentiation, presynaptic modulation of chemical synaptic transmission, regulation of calcium ion-dependent exocytosis
GO CC Complete:	exocytic vesicle, hippocampal mossy fiber to CA3 synapse, synaptic vesicle, membrane, synaptic vesicle membrane, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=18381\|UniProtKB=Q8IV01	Homo sapiens	LDO
GORGO\|Ensembl=ENSGGOG00000014969.3\|UniProtKB=G3RG69	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000011741.4\|UniProtKB=F7GWY8	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2159601\|UniProtKB=Q920N7	Mus musculus	LDO
RAT\|RGD=621876\|UniProtKB=P97610	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000003369.4\|UniProtKB=E1BEH9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000024837.4\|UniProtKB=I3LK76	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000025014.4\|UniProtKB=F6RKV7	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000007404.6\|UniProtKB=A0A337SR16	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845011643.1\|UniProtKB=A0A8I3NII1	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000007791.4\|UniProtKB=F7A959	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000011222.3\|UniProtKB=F7FBU6	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010022839.1\|UniProtKB=A0A8V0ZQC5	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000013607.4\|UniProtKB=A0A803TEG8	Anolis carolinensis	LDO
XENLA\|Gene=LOC108714929\|UniProtKB=A0A1L8GDL4	Xenopus laevis	O
XENLA\|Gene=syt12.L\|UniProtKB=A0A1L8GJA2	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-988426\|UniProtKB=A0A6I8PQA0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000001762.2\|UniProtKB=H2L8L9	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-081022-147\|UniProtKB=B3DJ38	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000001528.1\|UniProtKB=W5M038	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118406743\|UniProtKB=A0A9J7HNL5	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC579740\|UniProtKB=A0A7M7P0T7	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC115925107\|UniProtKB=A0A7M7P0T1	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0261085\|UniProtKB=Q9VYE1	Drosophila melanogaster	LDO
TRICA\|EnsemblGenome=TC032788\|UniProtKB=A0A139WIT9	Tribolium castaneum	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g247877\|UniProtKB=A7SX18	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g85661\|UniProtKB=A7RKX9	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g136167\|UniProtKB=A7SX19	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g115870\|UniProtKB=A7SEZ4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g136571\|UniProtKB=A7SXC9	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g130783\|UniProtKB=A7ST77	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g136185\|UniProtKB=A7SX17	Nematostella vectensis	O
TRIAD\|Gene_ORFName=TRIADDRAFT_61791\|UniProtKB=B3SBZ4	Trichoplax adhaerens	O