PANTHER Gene Information

Gene Symbol(s):

TMPRSS12

Organism:

Pan troglodytes

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Tree

Gene Name:

Transmembrane serine protease 12

Gene ID:

ENSPTRG00000004942.5

Protein ID:

H2Q5X2

Persistent Id:

PTN000666912

Alternate Ids:

XM_522598(refSeq)	114644751(GI)
ENSPTRP00000008440(Ensembl_PRO)	467200(GeneID)
ENSPTRT00000009131(Ensembl_TRS)	H2Q5X2_PANTR(UniProtKB-ID)
H2Q5X2(Synonym)	AACZ04012910(EMBL)
ENSPTRG00000004942(Ensembl)
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PANTHER Classification

PANTHER Family:	TRANSMEMBRANE PROTEASE SERINE (PTHR24253)
PANTHER Subfamily:	TRANSMEMBRANE PROTEASE SERINE 12 (PTHR24253:SF146)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	serine protease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	serine-type endopeptidase activity, serine-type peptidase activity
GO BP Complete:	acrosome assembly, binding of sperm to zona pellucida, positive regulation of sperm capacitation, spermatogenesis, proteolysis, protein processing
GO CC Complete:	acrosomal vesicle, membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=28779\|UniProtKB=Q86WS5	Homo sapiens	LDO
GORGO\|Ensembl=ENSGGOG00000004170.3\|UniProtKB=G3QNH6	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000018484.4\|UniProtKB=F6X231	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1922252\|UniProtKB=Q3V0Q7	Mus musculus	LDO
RAT\|RGD=2323781\|UniProtKB=F1M348	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000050872.1\|UniProtKB=A0A3Q1M0B8	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00005011170.1\|UniProtKB=A0A4X1WDM1	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000009548.4\|UniProtKB=F6YJM9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000018533.5\|UniProtKB=A0A337SWU7	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000005093.4\|UniProtKB=F6ZEH9	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000004933.4\|UniProtKB=F7AUF7	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000002558.4\|UniProtKB=F7FL69	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010022287.1\|UniProtKB=A0A8V0ZPI0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000041333.1\|UniProtKB=A0A803SMH5	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000035160.1\|UniProtKB=A0A803TZF9	Anolis carolinensis	LDO
ANOCA\|Ensembl=ENSACAG00000042903.1\|UniProtKB=A0A803TFK3	Anolis carolinensis	O
XENLA\|Gene=prss8l.3.L\|UniProtKB=A0A8J1LTJ6	Xenopus laevis	O
XENLA\|Gene=LOC108703882\|UniProtKB=A0A8J1LSK6	Xenopus laevis	O
XENLA\|Gene=LOC108703285\|UniProtKB=A0A8J0U4R5	Xenopus laevis	O
XENLA\|Gene=prss8l.3.S\|UniProtKB=A0A8J1LZF2	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000032868\|UniProtKB=A0A6I8PMQ8	Xenopus tropicalis	O
XENLA\|Gene=LOC108703872\|UniProtKB=A0A8J0TVL3	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000048337\|UniProtKB=A0A803JU46	Xenopus tropicalis	O
XENLA\|Gene=LOC121398115\|UniProtKB=A0A8J1LSW7	Xenopus laevis	O
XENLA\|Gene=prss8l.1.L\|UniProtKB=A0A8J0U3A2	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000006281\|UniProtKB=F7DXT6	Xenopus tropicalis	O
XENLA\|Gene=prss8l.4.S\|UniProtKB=A0A8J1LXZ3	Xenopus laevis	O
XENLA\|Gene_Synonym=prss8l.5.S\|UniProtKB=A0A1L8ERH1	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000032140\|UniProtKB=A0A6I8SUY8	Xenopus tropicalis	O
XENTR\|Gene=LOC116407645\|UniProtKB=A0A8J1IUF4	Xenopus tropicalis	O
XENTR\|Gene=prss8l100494289\|UniProtKB=A0A8J1IUV6	Xenopus tropicalis	O
XENTR\|Xenbase=XB-GENE-22167980\|UniProtKB=F7DXA1	Xenopus tropicalis	O
XENLA\|Gene=LOC108703966\|UniProtKB=A0A8J0U497	Xenopus laevis	O
XENTR\|Gene=LOC105948396\|UniProtKB=A0A8J1IUG5	Xenopus tropicalis	O
XENLA\|Gene=LOC108703964\|UniProtKB=A0A8J0TVR5	Xenopus laevis	O
XENLA\|Gene=MGC116527\|UniProtKB=A0A8J1LQZ9	Xenopus laevis	O
XENLA\|Gene=LOC108703965\|UniProtKB=A0A8J0U304	Xenopus laevis	O
XENTR\|Gene=LOC100494613\|UniProtKB=A0A8J0QTF5	Xenopus tropicalis	O
XENTR\|Ensembl=ENSXETG00000025971\|UniProtKB=F7DXM3	Xenopus tropicalis	O
XENTR\|Gene=prss27\|UniProtKB=A0A8J1IWT8	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000006351.2\|UniProtKB=H2LPJ6	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000001135.1\|UniProtKB=W5LYS8	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000000039.1\|UniProtKB=W5LV88	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000001165.1\|UniProtKB=W5LYV8	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000001116.1\|UniProtKB=W5LYQ2	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000000055.1\|UniProtKB=W5LVA8	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000000041.1\|UniProtKB=W5LV91	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000000213.1\|UniProtKB=W5LVT5	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000000364.1\|UniProtKB=W5LWA6	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000000780.1\|UniProtKB=W5LXL0	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000000033.1\|UniProtKB=W5LV80	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000000053.1\|UniProtKB=W5LVA4	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000000167.1\|UniProtKB=W5LVM9	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000003573.1\|UniProtKB=W5M790	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000001075.1\|UniProtKB=W5LYK3	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000000377.1\|UniProtKB=W5LWA3	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000000732.1\|UniProtKB=W5LXF7	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000000044.1\|UniProtKB=W5LV95	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000000030.1\|UniProtKB=W5LV78	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000000753.1\|UniProtKB=W5LXI2	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000000054.1\|UniProtKB=W5LVA7	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000000036.1\|UniProtKB=W5LV83	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000006549.2\|UniProtKB=H2LQ87	Oryzias latipes	O
DANRE\|Gene=si=dkey-32n7.7\|UniProtKB=A0A8M9Q8R0	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000000256.2\|UniProtKB=A0A3B3HRI3	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000026241.1\|UniProtKB=A0A3B3I9T3	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000024823.1\|UniProtKB=A0A3B3H9U6	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000022022.1\|UniProtKB=A0A3B3HJY1	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000000282.2\|UniProtKB=H2L3L9	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000030280.1\|UniProtKB=A0A3B3HYH9	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000025385.1\|UniProtKB=A0A3B3IB90	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000001206.2\|UniProtKB=A0A3B3I579	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000000242.2\|UniProtKB=A0A3B3HCG3	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000021926.1\|UniProtKB=A0A3B3HDH5	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000000252.2\|UniProtKB=A0A3B3IEF1	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000024648.1\|UniProtKB=A0A3B3I9W2	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000023553.1\|UniProtKB=A0A3B3HB40	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000001175.2\|UniProtKB=H2L6J3	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000001209.2\|UniProtKB=H2L6N7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000006587.2\|UniProtKB=H2LQC6	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000008481.2\|UniProtKB=H2LX01	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000028700.1\|UniProtKB=A0A3B3IGH9	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000025103.1\|UniProtKB=A0A3B3I9T8	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000025659.1\|UniProtKB=A0A3B3IPI9	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000018580.2\|UniProtKB=H2MWI2	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000001213.2\|UniProtKB=H2L6P3	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000030405.1\|UniProtKB=A0A3B3H3B3	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-070720-11\|UniProtKB=F1Q9Z9	Danio rerio	O
DANRE\|Gene=prss60.3\|UniProtKB=A0A8M1RHA5	Danio rerio	O
DANRE\|Gene=LOC100535114\|UniProtKB=A0A8M3APS8	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-050320-109\|UniProtKB=A8E5D9	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-070424-25\|UniProtKB=A4FVH9	Danio rerio	O
DANRE\|Gene=si=ch73-182e20.4\|UniProtKB=A0A8M3B791	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-040801-33\|UniProtKB=A0A0R4IRW8	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000000028.1\|UniProtKB=W5LV75	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000000042.1\|UniProtKB=W5LV93	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000003449.3\|UniProtKB=F6WXY4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000020629.1\|UniProtKB=H2XQG4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000012084.2\|UniProtKB=F6XVK2	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000001370.3\|UniProtKB=F6S9V9	Ciona intestinalis	O
BRAFL\|Gene=LOC118407680\|UniProtKB=A0A9J7HQK0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118406062\|UniProtKB=A0A9J7HLJ5	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC594731\|UniProtKB=A0A7M7SZC5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC756308\|UniProtKB=A0A7M7P3U8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC588084\|UniProtKB=A0A7M7SZU0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100890793\|UniProtKB=A0A7M7NU74	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC753460\|UniProtKB=A0A7M7P0R8	Strongylocentrotus purpuratus	O
PRIPA\|EnsemblGenome=WBGene00206066\|UniProtKB=A0A2A6BXF2	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0033363\|UniProtKB=A1Z7M5	Drosophila melanogaster	O
TRICA\|EnsemblGenome=TC008657\|UniProtKB=D6WT56	Tribolium castaneum	O
DROME\|FlyBase=FBgn0033365\|UniProtKB=A1Z7M7	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP009000\|UniProtKB=A0A1S4H0L6	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC008653\|UniProtKB=D6WT60	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_49881\|UniProtKB=E9GFB8	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW012701\|UniProtKB=B7QAI1	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW015718\|UniProtKB=B7P1X4	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW001619\|UniProtKB=B7P4W5	Ixodes scapularis	O
DROME\|FlyBase=FBgn0286782\|UniProtKB=B7YZU2	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP008995\|UniProtKB=A0A1S4GZT1	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC033856\|UniProtKB=A0A139WEY0	Tribolium castaneum	O
IXOSC\|EnsemblGenome=ISCW001620\|UniProtKB=B7P4W6	Ixodes scapularis	O
DROME\|FlyBase=FBgn0035501\|UniProtKB=Q9VZH5	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP002811\|UniProtKB=A0A1S4GG73	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP013089\|UniProtKB=F5HKL0	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP002813\|UniProtKB=Q7QCV0	Anopheles gambiae	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_226573\|UniProtKB=E9H0K2	Daphnia pulex	O
DROME\|FlyBase=FBgn0033192\|UniProtKB=A1Z709	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP004571\|UniProtKB=A0A1S4GM58	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP004568\|UniProtKB=A0A1S4GLF3	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP008649\|UniProtKB=A0A1S4GYV4	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP004570\|UniProtKB=A0A1S4GM14	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP012037\|UniProtKB=Q7PZR2	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP006631\|UniProtKB=A0A1S4GSR0	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC000250\|UniProtKB=D6WBS5	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC007026\|UniProtKB=D2A2P2	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC010781\|UniProtKB=D6W7Q1	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_347753\|UniProtKB=E9GLZ3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_347752\|UniProtKB=E9GLZ2	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_347754\|UniProtKB=E9GLZ6	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_317027\|UniProtKB=E9GEP9	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW024505\|UniProtKB=B7PWZ1	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW002979\|UniProtKB=B7P8G5	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG178982\|UniProtKB=T1FE04	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g198217\|UniProtKB=A7RJY0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g127465\|UniProtKB=A7SQF1	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g111870\|UniProtKB=A7SB63	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g130234\|UniProtKB=A7SSR9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g109826\|UniProtKB=A7S9G1	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g230861\|UniProtKB=A7SSS0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g41116\|UniProtKB=A7SZI9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g109239\|UniProtKB=A7S8Y5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g88458\|UniProtKB=A7RP61	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g124644\|UniProtKB=A7SNB8	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG61839\|UniProtKB=B3SC39	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG25686\|UniProtKB=B3RY71	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG53235\|UniProtKB=B3RNP0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG18710\|UniProtKB=B3RIF5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG5625\|UniProtKB=B3RYJ8	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG26286\|UniProtKB=B3RZF9	Trichoplax adhaerens	O