The mission of the PANTHER knowledgebase is to support biomedical and other research by providing
comprehensive information about the evolution of protein-coding gene families, particularly
protein phylogeny, function and genetic variation impacting that function. Learn more

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Current Release: PANTHER 19.0 | 15,683 family phylogenetic trees | 144 species | News
Whole genome function views

PANTHER Gene Information

Gene Symbol(s):

KRT18

Organism:

Pan troglodytes

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Tree

Gene Name:

Keratin 18

Gene ID:

ENSPTRG00000004996.4

Protein ID:

H2Q609

Persistent Id:

PTN000580127

Alternate Ids:

AACZ04012929(EMBL)	H2Q609_PANTR(UniProtKB-ID)
ENSPTRG00000004996(Ensembl)	JAA25640(EMBL-CDS)
XP_509083(refSeq)	114644548(GI)
ENSPTRT00000009202(Ensembl_TRS)	H2Q609(Synonym)
451923(GeneID)	ENSPTRP00000008508(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	INTERMEDIATE FILAMENT (PTHR23239)
PANTHER Subfamily:	KERATIN, TYPE I CYTOSKELETAL 18 (PTHR23239:SF349)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	intermediate filament cytoskeleton organization
PANTHER GO-slim Cellular Component:	keratin filament
PANTHER protein class:	intermediate filament

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	scaffold protein binding, structural molecule activity
GO BP Complete:	negative regulation of apoptotic process, intermediate filament cytoskeleton organization, Golgi to plasma membrane protein transport
GO CC Complete:	cytoskeleton, keratin filament, microtubule organizing center, cytoplasm, centriolar satellite, cytosol, intermediate filament

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

-

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6430\|UniProtKB=P05783	Homo sapiens	LDO
GORGO\|Ensembl=ENSGGOG00000025508.2\|UniProtKB=G3SE94	Gorilla gorilla gorilla	O
GORGO\|Ensembl=ENSGGOG00000024155.2\|UniProtKB=A0A2I2ZWP5	Gorilla gorilla gorilla	O
GORGO\|Ensembl=ENSGGOG00000010157.3\|UniProtKB=G3R3T2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000043308.2\|UniProtKB=A0A5F7ZHW8	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000031911.3\|UniProtKB=F6VBK4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=96692\|UniProtKB=P05784	Mus musculus	LDO
RAT\|RGD=150343399\|UniProtKB=A0A8I6A244	Rattus norvegicus	O
RAT\|RGD=619935\|UniProtKB=Q5BJY9	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000001517.6\|UniProtKB=F6S1Q0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000000253.5\|UniProtKB=A0A5G2RBD3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000038379.3\|UniProtKB=A0A9L0QY80	Equus caballus	LDO
HORSE\|Ensembl=ENSECAG00000002256.4\|UniProtKB=F6VY00	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000000299.6\|UniProtKB=M3VUH3	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845023645.1\|UniProtKB=A0A8I3PJ84	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000036454.1\|UniProtKB=A0A5F8GUW7	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000045852.1\|UniProtKB=A0A6I8PG64	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024018.1\|UniProtKB=A0A8V1A2T7	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000011762.4\|UniProtKB=H9GI59	Anolis carolinensis	LDO
XENLA\|Gene=krt18-a\|UniProtKB=P08802	Xenopus laevis	O
XENLA\|Gene=krt18-b\|UniProtKB=Q7SY65	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000016545.2\|UniProtKB=H2MPQ2	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040426-1508\|UniProtKB=Q6PHE4	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000001491.2\|UniProtKB=H2L7M8	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000001481.2\|UniProtKB=H2L7M4	Oryzias latipes	LDO
DANRE\|Gene=si=ch211-133j6.3\|UniProtKB=A0A8N7TEZ1	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-030411-6\|UniProtKB=Q7ZTS4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000005463.1\|UniProtKB=W5MDY8	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118405578\|UniProtKB=A0A9J7HMI6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118403465\|UniProtKB=A0A9J7KGN5	Branchiostoma floridae	O